Learning and memory processes of an ACTH"4"-"9 analog (ebiratide; Hoe 427) in mice and rats - Hock, F.J.; Gerhards, H.J.; Wiemer, G.; Usinger, P.; Geiger, R. (Elsevier)
These experiments investigated the effects of the new ACTH"4"-"9 analog ebiratide (Hoe 427) [H-Met(O"2)-Glu-His-Phe-D-Lys-Phe-NH-(CH"2)"8-NH"2x3 CH"3COOH] on memory processes in mice and rats in five training tasks. With all five training and testing procedures (inhibitory avoidance test with ECS- or scopolamine-induced amnesia, up-hill avoidance, one-way shuttle box avoidance and eight-arm radial maze) ebiratide was most effective in a dose range of 1-10 μg/kg SC.
http://linkinghub.elsevier.com/retrieve/pii/0196-9781(88)90167-2
Keywords: V