Structure-activity relationships in photosystem II inhibition by 5-acyl-3-(1-aminoalkylidene)-4-hydroxy-2H-pyran-2,6(3H)-dione derivatives - Yoneyama, K.; Nakajima, Y.; Konnai, M.; Iwamura, H.; Asami, T.; Takahashi, N.; Yoshida, S. (Elsevier)
Quantitative structure-activity relationships in photosystem II (PS II) inhibition by 5-acyl-3-(1-aminoalkylidene)-4-hydroxy-2H-pyran-2,6(3H)-dione derivatives were analyzed. The results demonstrate that overall lipophilicity of the molecule is a major determinant for the activity as in the case for typical PS II inhibitors including phenylurea herbicides. In addition, the activity of the substituted N-benzyl derivatives was found to depend not only on the lipophilicity but also on both the electronic and steric characters of the substituents.
http://dx.doi.org/10.1016/0048-3575(91)90083-X
Keywords: ZA-ZE