Confirmation of linkage of Friedreich ataxia to chromosome 9 and identification of a new closely linked marker - Fujita, R.; Agid, Y.; Trouillas, P.; Seck, A.; Tommasi-Davenas, C.; Driesel, A.J.; Olek, K.; Grzeschik, K.-H.; Hanauer, A.; Mandel, J.L.; Nakamura, Y. (Elsevier)
A linkage analysis with chromosome 9 markers was performed in 33 families with Friedreich ataxia (FA). Linkage with D9S15, previously established by S. Chamberlain et al. (1988, Nature London 334: 248-249) was confirmed in our sample (z(θ) = 6.82 at θ = 0.02) while INFB (interferon-β gene) shows looser linkage. An additional marker, D9S5, was also shown to be closely linked to FA (z(θ) = 5.77 at θ = 0.00).
http://dx.doi.org/10.1016/0888-7543(89)90323-6
Keywords: W; WW-YZ