Characterization of Three Overlapping Deletions Causing X-Linked Lymphoproliferative Disease - Skare, J.; Wu, B.-L.; Madan, S.; Pulijaal, V.; Purtilo, D.; Haber, D.; Nelson, D.; Sylla, B.; Milunsky, A.; White, B.; Housman, D.; Lenoir, G.; et al. (Elsevier)
Blot hybridization was used to find DNA sequences missing in a male who lacked two-thirds of Xq25. The probes were used to (discover two additional males with deletions resulting in X-linked lymphoproliferative disease (XLP). All three deletions have a region in common, and DXS739 is within this candidate region. The new deletions were also detectable rising chromosome banding, and the smallest removes only one-third of Xq25. XLP is the only consequence of the deletions.
http://dx.doi.org/10.1006/geno.1993.1169
Keywords: W; WW-YZ