Binding site of the rat liver specific monoclonal antibody - Sato, K.; Ikeda, T.; Osada, Y. (Elsevier)
A rat liver-specific antigen (RLSA) lost its binding ability to the corresponding monoclonal antibody after treatment with N-glycanase or sialidase, which suggested that the specific binding site might be in a portion of the sugar chain containing sialic acid. The specific antigen reacted with wheat germ agglutinin, lentil lectin, erythroagglutinating phytohemagglutinin and Ricinus communis agglutinin, but not with concanavalin A or peanut agglutinin. These results suggest that the specific antigen has asparagine-linked complex-type sugar chains which might be the binding sites of the monoclonal antibody.
http://dx.doi.org/10.1016/S0006-291X(88)80403-0
Keywords: W; V; U