Synthesis of phellanphos, an efficient chiral 1,2-diphosphine for asymmetric catalysis - Lauer, M.; Samuel, O.; Kagan, H.B. (Elsevier)
A chiral 1,2-diphosphine was prepared in two steps from ()-α-phellandrene. This phosphine phellanphos gives a cationic rhodium complex (phellanphos-cyclooctadienerhodium hexafluorophosphate) which catalyses asymmetric reductions. N-Acetylphenylalanine and N-acetylalanine have been prepared in 94-95% enantiomeric excess.
http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)92357-X
Keywords: V