Addition compounds of alkali metal hydrides - Brown, H.C.; Krishnamurthy, S.; Hubbard, J.L. (Elsevier)
Addition of one mole equivalent of trialkylborane to a tetrahydrofuran (THF) solution of lithium trimethoxyaluminohydride (LTMA) at room temperature results in a facile and rapid displacement of aluminum methoxide as a polymeric gel, producing the corresponding lithium trialkylborohydride in quantitative yield. The reaction is quite general and applicable to trialkylboranes of widely varied structural requirements. The trialkylborohydrides thus produced can be directly utilized for the stereoselective reduction of organic functional groups without the necessity of removing aluminum methoxide. The present reaction provides a general, convenient in situ synthesis of lithium trialkylborohydrides where this is required in synthetic transformations.
http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)82544-9
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