Mutational analysis of enhancer domains responsive to trans-activation by the X gene of human hepatitis B virus
Goodarzi, G. ; Ohno, H. ; Adams, R. ; Darabi, A. ; Tewari, A. ; Watabe, M. ; Watabe, K.
Springer
Published 1990
Springer
Published 1990
| ISSN: |
1432-8798
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Summary The X gene product of human hepatitis B virus (HBV) trans-activates the HBV enhancer. In order to identify domains responsive to trans-activation by the X gene, we introduced a series of mutations into the HBV enhancer and assayed the enhancer activities in the presence of the X gene product. Our results suggest that the EP domain of the enhancer is essential for trans-activation by the X gene.
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| Type of Medium: |
Electronic Resource
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| URL: |