The effect of dexamethasone on the course ofEchinostoma caproni andE. trivolvis infections in the golden hamster (Mesocricetus auratus)
| ISSN: |
1432-1955
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Abstract Golden hamsters (Mesocricetus auratus) were given intramuscular injections of dexamethasone and infected withEchinostoma caproni orE. trivolvis. All animals were necropsied on day 14 postinfection. Dexamethasone treatment at high doses resulted in increased parasite recovery. Decreased total white blood cell counts and decreased relative splenic weights were observed in corticosteroid-treated hamsters. Dexamethasone-treated animals also demonstrated significantly lower mean parasite dry weights forE. caproni. Specific serum IgG against the parasites was not detected in corticosteroid-treated hamsters on day 14 postinfection.
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| Type of Medium: |
Electronic Resource
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| URL: |