Isolated meningeal chloroma (granulocytic sarcoma) – a case report and review of the literature
| ISSN: |
1432-0584
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| Keywords: |
Key words Chloroma ; Acute myeloblastic leukemia ; Chemotherapy ; Autologous stem cell transplantation
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract Isolated chloromas (granulocytic sarcomas) are rare tumors, most of them progressing to acute myeloblastic leukemia within months. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and prolong survival. We report on a patient with isolated meningeal chloroma, primarily misdiagnosed as a high-grade Non-Hodgkin's lymphoma. Two cycles of antileukemic induction chemotherapy were administered, followed by local irradiation and intensified consolidation therapy with autologous stem cell transplantation. After 20 months, he is still in complete remission.
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| Type of Medium: |
Electronic Resource
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| URL: |