Analysis of HSV isolated from patients with unilateral and bilateral herpetic keratitis
Tognon, M. ; Manservigi, R. ; Sebastiani, A. ; Bragliani, G. ; Busin, M. ; Cassai, E.
Springer
Published 1985
Springer
Published 1985
| ISSN: |
1573-2630
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|---|---|
| Keywords: |
herpes simplex virus (HSV) ; herpes simplex keratitis (HSK) ; restriction enzyme analysis ; drug resistance
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Summary Restriction enzyme analysis was utilized to investigate 11 HSV isolates from patients with herpetic keratitis. The electrophoretic profiles of the DNAs indicate that the isolates belong to HSV-1 and are epidemiologically unrelated. Two of the isolates, derived from a patient with simultaneous bilateral herpetic keratitis were further characterized by genetic and phenotypic analyses. These studies showed the following: (i) the two recrudescent lesions were caused by the same HSV-1 isolate; (ii) the isolate yielded two different plaque phenotypes; (iii) these plaques showed different sensitivity to I.D.U.
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| Type of Medium: |
Electronic Resource
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| URL: |