The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia - Stein, E. M., Garcia-Manero, G., Rizzieri, D. A., Tibes, R., Berdeja, J. G., Savona, M. R., Jongen-Lavrenic, M., Altman, J. K., Thomson, B., Blakemore, S. J., Daigle, S. R., Waters, N. J., Suttle, A. B., Clawson, A., Pollock, R., Krivtsov, A., Armstrong, S. A., Di; Martino, J., Hedrick, E., Löwenberg, B., Tallman, M. S. (American Society of Hematology (ASH), 2018)
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