Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation]
Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney
National Academy of Sciences
Published 2018
National Academy of Sciences
Published 2018
| Publication Date: |
2018-02-14
|
|---|---|
| Publisher: |
National Academy of Sciences
|
| Print ISSN: |
0027-8424
|
| Electronic ISSN: |
1091-6490
|
| Topics: |
Biology
Medicine
Natural Sciences in General
|
| Published by: |
| _version_ | 1836398792615657473 |
|---|---|
| autor | Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney |
| beschreibung | Lipocalin-2 (Lcn2), a critical component of the innate immune response which binds siderophores and limits bacterial iron acquisition, can elicit spillover adverse proinflammatory effects. Here we show that holo-Lcn2 (Lcn2–siderophore–iron, 1:3:1) increases mitochondrial reactive oxygen species (ROS) generation and attenuates mitochondrial oxidative phosphorylation in adult rat primary cardiomyocytes in a... |
| citation_standardnr | 6164714 |
| datenlieferant | ipn_articles |
| feed_id | 113 |
| feed_publisher | National Academy of Sciences |
| feed_publisher_url | http://www.nasonline.org/ |
| insertion_date | 2018-02-14 |
| journaleissn | 1091-6490 |
| journalissn | 0027-8424 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | National Academy of Sciences |
| quelle | PNAS - Proceedings of the National Academy of Sciences |
| relation | http://www.pnas.org/content/115/7/1576.short?rss=1 |
| search_space | articles |
| shingle_author_1 | Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney |
| shingle_author_2 | Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney |
| shingle_author_3 | Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney |
| shingle_author_4 | Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney |
| shingle_catch_all_1 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] Lipocalin-2 (Lcn2), a critical component of the innate immune response which binds siderophores and limits bacterial iron acquisition, can elicit spillover adverse proinflammatory effects. Here we show that holo-Lcn2 (Lcn2–siderophore–iron, 1:3:1) increases mitochondrial reactive oxygen species (ROS) generation and attenuates mitochondrial oxidative phosphorylation in adult rat primary cardiomyocytes in a... Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_2 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] Lipocalin-2 (Lcn2), a critical component of the innate immune response which binds siderophores and limits bacterial iron acquisition, can elicit spillover adverse proinflammatory effects. Here we show that holo-Lcn2 (Lcn2–siderophore–iron, 1:3:1) increases mitochondrial reactive oxygen species (ROS) generation and attenuates mitochondrial oxidative phosphorylation in adult rat primary cardiomyocytes in a... Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_3 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] Lipocalin-2 (Lcn2), a critical component of the innate immune response which binds siderophores and limits bacterial iron acquisition, can elicit spillover adverse proinflammatory effects. Here we show that holo-Lcn2 (Lcn2–siderophore–iron, 1:3:1) increases mitochondrial reactive oxygen species (ROS) generation and attenuates mitochondrial oxidative phosphorylation in adult rat primary cardiomyocytes in a... Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_4 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] Lipocalin-2 (Lcn2), a critical component of the innate immune response which binds siderophores and limits bacterial iron acquisition, can elicit spillover adverse proinflammatory effects. Here we show that holo-Lcn2 (Lcn2–siderophore–iron, 1:3:1) increases mitochondrial reactive oxygen species (ROS) generation and attenuates mitochondrial oxidative phosphorylation in adult rat primary cardiomyocytes in a... Erfei Song, Sofhia V. Ramos, Xiaojing Huang, Ying Liu, Amy Botta, Hye Kyoung Sung, Patrick C. Turnbull, Michael B. Wheeler, Thorsten Berger, Derek J. Wilson, Christopher G. R. Perry, Tak W. Mak, Gary Sweeney National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_title_1 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| shingle_title_2 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| shingle_title_3 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| shingle_title_4 | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| timestamp | 2025-06-30T23:32:43.159Z |
| titel | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| titel_suche | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes [Immunology and Inflammation] |
| topic | W WW-YZ TA-TD |
| uid | ipn_articles_6164714 |