Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus

Chafiq Hamdouchi, Pranab Maiti, Alan M. Warshawsky, Amy C. De; Baillie, Keith A. Otto, Kelly L. Wilbur, Steven D. Kahl, Anjana Patel Lewis, Guemalli R. Cardona, Richard W. Zink, Keyue Chen, Siddaramaiah CR, Jayana P. Lineswala, Grace L. Neathery, Cecilia Bouaichi, Benjamin A. Diseroad, Alison N. Campbell, Stephanie A. Sweetana, Lisa A. Adams, Over Cabrera, Xiaosu Ma, Nathan P. Yumibe, Chahrzad Montrose-Rafizadeh, Yanyun Chen and Anne Reifel Miller
American Chemical Society (ACS)
Published 2018