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International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 3 ( 2022-09-02), p. 817-824

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1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 83, No. 3 ( 2004-2), p. 245-248

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 3 ( 2022-09-03), p. 997-1003

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1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2004-3), p. 77-84

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2004-3), p. 107-116

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 3 ( 2022-09-05), p. 825-836

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1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2004-3), p. 151-160

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2004-3), p. 173-182

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2004-3), p. 197-198

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 1 ( 2004-3), p. 13-19

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 1 ( 2004-3), p. 21-32

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0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-09), p. 1413-1435

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1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-17), p. 1169-1173

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1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-17), p. 1229-1240

To analyse and quantify ocular surface parameters in patients with unilateral neurotrophic keratitis (NK) induced by trigeminal nerve injury post-neurosurgery. Methods The study included 26 unilateral NK patients who had undergone neurosurgery, and 20 matched normal controls. Demographic and clinical characteristics of all participants were collected and analysed. Slit-lamp examination, Cochet–Bonnet aesthesiometry, Keratograph 5 M, and LipiView interferometer were performed on both eyes of 17 mild NK patients. For nine moderate/severe NK patients, sub-basal nerve density was measured by in vivo confocal microscopy. Results Of the 26 patients, nine had acoustic neuroma, nine had trigeminal neuralgia, and eight had neoplasms. Facial nerve paralysis was observed in one of the 17 mild NK eyes (5.9%) and seven of the nine moderate/severe NK eyes (77.8%). Compared to contralateral and normal control eyes, 26 NK eyes showed significantly reduced sensitivity in five corneal regions ( P   〈   0.05). Corneal sensitivity in moderate/severe NK eyes was significantly lower than in mild NK eyes ( P   〈   0.05). Moderate/severe NK eyes had poor visual acuity, and their sub-basal nerve density was lower than that of the controls. The onset of the moderate/severe NK was from 0.5 to 24 months (median [Q1, Q3], 1 [0.5, 2.5] months) after neurosurgery. For the mild NK eyes, the number of total blinks, the first non-invasive tear breakup time (NITBUT) and average NITBUT were significantly lower than contralateral and normal control eyes ( P   〈   0.05), and the number of partial blinks and partial blinking rate were significantly higher than the other two control groups ( P   〈   0.05). Conclusions Patients with NK induced by trigeminal nerve injury following neurosurgery had decreased corneal sensitivity to various degrees accompanied by increased partial blinks and shortened NITBUT. The severity of NK is related to the severity of the corneal sensory impairment. Facial nerve paralysis can worsen the clinical progression of NK. Trial registration Chinese Clinical Trial Registry (ChiCTR2100044068, Date of Registration: March 9, 2021).

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-23), p. 1185-1192

To analyze the choroidal thickness between patients with keratoconus undergoing cross-linking treatment and a healthy population, as well as to determine the factors that influence choroidal thickness. Methods This was an observational, analytical, case–control study that was conducted from February 2021 to June 2021. Choroidal thickness was measured at different locations, including the subfoveal, nasal (1000 μm), temporal (1000 μm), superior (1000 μm) and inferior (1000 μm) locations using a Spectral-domain optical coherence tomography with enhanced depth imaging, which allowed us to obtain horizontal and vertical B-scans centered on the fovea. Results This study included 21 patients with keratoconus (mean age, 21.86 ± 5.28 years) and 28 healthy patients (mean age, 24.21 ± 4.71 years). Choroidal thickness was significantly greater in patients with keratoconus than in healthy patients in each of the following measured locations: subfoveal ( P   〈  0.001); nasal (1000 μm) ( P   〈  0.001), temporal (1000 μm) ( P   〈  0.001), superior (1000 μm) ( P   〈  0.001) and inferior (1000 μm) ( P   〈  0.001) locations. Variables such as age ( ρ  = − 0.09; P  = 0.50) and refraction ( ρ  = 0.14; P  = 0.34) were not found to be associated with choroidal thickness. In a stepwise multiple linear regression, the group was the single variable correlated with choroidal thickness ( β  = 0.88; P   〈  0.001). Conclusion Choroidal thickness is thicker in keratoconus patients treated with cross-linking than in the healthy population. This finding could be associated with inflammatory choroidal mechanisms in keratoconus patients, but more studies are needed. Age and refractive error do not seem to influence choroidal thickness.

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

Breast Cancer Research and Treatment, Springer Science and Business Media LLC, Vol. 84, No. 3 ( 2004-4), p. 293-293

Online Resource

0167-6806, 1573-7217

English

Springer Science and Business Media LLC

2004

2004077-5

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-23), p. 1317-1324

The aim of this study was to evaluate ocular and systemic risk factors for posterior chamber intraocular lens dislocation, as well as forms of manifestation. Methods A retrospective case–control study were all patients presented in the period 2012–2016 having intraocular lens dislocation and being treated with implantation of an iris-fixated intraocular lens was conducted at the University Hospital Mainz. As controls, pseudophakic patients presenting for other reasons were included. Results 150 eyes of 150 patients (mean age 72.7 ± 12.4 years, range 24–93 years) with IOL dislocation and 150 eyes of 103 controls were included in this study. The average time between primary implantation and IOL luxation was 86 months (iQR: 39.25–127 months) for all dislocations. Previous pars plana vitrectomy (PPV) (crudeOR = 2.14 (95% CI 1.23, 3.72), p  = 0.011) and PEX (crudeOR = 11.6 (4.79, 28.12), p   〈  0.001) was linked with a higher risk of IOL luxation. Luxation occurs also earlier in patients with previous PPV and PEX than in eyes with neither PEX nor previous PPV (82.2 vs. 127 months). Rhegmatogenous retinal detachment was the major pathology that required a previous PPV for eyes with an IOL dislocation (57%). The average time between PPV and IOL dislocation was 74.67 months (range 0–186 months). Conclusion Patients with a coexistence of both: PEX and a previous PPV had an elevated risk of IOL dislocation, and also had a shorter time interval between primary IOL implantation and IOL dislocation followed by eyes with PEX only and eyes with only a previous PPV.

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-23), p. 1337-1343

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8

International Ophthalmology, Springer Science and Business Media LLC, Vol. 43, No. 4 ( 2022-09-23), p. 1353-1362

Online Resource

1573-2630

English

Springer Science and Business Media LLC

2022

2009810-8