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1Articles: DFG German National LicensesPaciorek, Tomasz ; Zažímalová, Eva ; Ruthardt, Nadia ; Petrášek, Jan ; Stierhof, York-Dieter ; Kleine-Vehn, Jürgen ; Morris, David A. ; Emans, Neil ; Jürgens, Gerd ; Geldner, Niko ; Friml, Jirí
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] One of the mechanisms by which signalling molecules regulate cellular behaviour is modulating subcellular protein translocation. This mode of regulation is often based on specialized vesicle trafficking, termed constitutive cycling, which consists of repeated internalization and recycling of ...Type of Medium: Electronic ResourceURL: -
2Articles: DFG German National LicensesMurata, Yoshimichi ; Iwasaki, Hirohide ; Sasaki, Mari ; Inaba, Kazuo ; Okamura, Yasushi
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Changes in membrane potential affect ion channels and transporters, which then alter intracellular chemical conditions. Other signalling pathways coupled to membrane potential have been suggested but their underlying mechanisms are unknown. Here we describe a novel protein from the ascidian ...Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesDiLuzio, Willow R. ; Turner, Linda ; Mayer, Michael ; Garstecki, Piotr ; Weibel, Douglas B. ; Berg, Howard C. ; Whitesides, George M.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The motion of peritrichously flagellated bacteria close to surfaces is relevant to understanding the early stages of biofilm formation and of pathogenic infection. This motion differs from the random-walk trajectories of cells in free solution. Individual Escherichia coli cells swim in ...Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesJones, Chris D. ; Cox, Peter M. ; Andreae, Meinrat O.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Atmospheric aerosols counteract the warming effects of anthropogenic greenhouse gases by an uncertain, but potentially large, amount. This in turn leads to large uncertainties in the sensitivity of climate to human perturbations, and therefore also in carbon cycle feedbacks and projections of ...Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesMonsalve, Gaspar ; Sheehan, Anne ; Pandey, M. R. ; Sapkota, Som ; Bilham, Roger ; Wu, Francis ; Schulte-Pelkum, Vera
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The rocks of the Indian subcontinent are last seen south of the Ganges before they plunge beneath the Himalaya and the Tibetan plateau. They are next glimpsed in seismic reflection profiles deep beneath southern Tibet, yet the surface seen there has been modified by processes within the ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesThe conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiaeKurz, Thimo ; Özlü, Nurhan ; Rudolf, Fabian ; O'Rourke, Sean M. ; Luke, Brian ; Hofmann, Kay ; Hyman, Anthony A. ; Bowerman, Bruce ; Peter, Matthias
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] SCF-type E3 ubiquitin ligases are multi-protein complexes required for polyubiquitination and subsequent degradation of target proteins by the 26S proteasome. Cullins, together with the RING-finger protein Rbx1, form the catalytic core of the ligase, and recruit the substrate-recognition ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The use of contrast agents and tracers in medical imaging has a long history. They provide important information for diagnosis and therapy, but for some desired applications, a higher resolution is required than can be obtained using the currently available medical imaging techniques. Consider, ...Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesGillet, Ph. ; El Goresy, A. ; Mostefaoui, S. ; Beck, P.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The accretion of the terrestrial planets from asteroid collisions and the delivery to the Earth of martian and lunar meteorites has been modelled extensively. Meteorites that have experienced shock waves from such collisions can potentially be used to reveal the accretion process at different ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The Sun and 〉15 per cent of nearby stars are surrounded by dusty disks that must be collisionally replenished by asteroids and comets, as the dust would otherwise be depleted on timescales 〈107 years (ref. 1). Theoretical studies show that the ...Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesBatlle, Eduard ; Bacani, Julinor ; Begthel, Harry ; Jonkeer, Suzanne ; Gregorieff, Alexander ; van de Born, Maaike ; Malats, Núria ; Sancho, Elena ; Boon, Elles ; Pawson, Tony ; Gallinger, Steven ; Pals, Steven ; Clevers, Hans
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Most sporadic colorectal cancers are initiated by activating Wnt pathway mutations, characterized by the stabilization of β-catenin and constitutive transcription by the β-catenin/T cell factor-4 (Tcf-4) complex. EphB guidance receptors are Tcf4 target genes that control intestinal ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesTobalske, Bret W. ; Powers, Donald R. ; Warrick, Douglas R.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Despite profound musculoskeletal differences, hummingbirds (Trochilidae) are widely thought to employ aerodynamic mechanisms similar to those used by insects. The kinematic symmetry of the hummingbird upstroke and downstroke has led to the assumption that these halves of the wingbeat cycle ...Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesReguera, Gemma ; McCarthy, Kevin D. ; Mehta, Teena ; Nicoll, Julie S. ; Tuominen, Mark T. ; Lovley, Derek R.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Microbes that can transfer electrons to extracellular electron acceptors, such as Fe(iii) oxides, are important in organic matter degradation and nutrient cycling in soils and sediments. Previous investigations on electron transfer to Fe(iii) have focused on the role of ...Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesReddy, L. ; Kreiman, G. ; Koch, C. ; Fried, I. ; Quiroga, R. Quian
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] It takes a fraction of a second to recognize a person or an object even when seen under strikingly different conditions. How such a robust, high-level representation is achieved by neurons in the human brain is still unclear. In monkeys, neurons in the upper stages of the ventral visual pathway ...Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesSluijs, Appy ; Kroon, Dick ; Zachos, James C. ; Thomas, Ellen ; Röhl, Ursula ; Bowles, Julie ; Raffi, Isabella ; Lourens, Lucas J.
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] At the boundary between the Palaeocene and Eocene epochs, about 55 million years ago, the Earth experienced a strong global warming event, the Palaeocene–Eocene thermal maximum. The leading hypothesis to explain the extreme greenhouse conditions prevalent during this period is the ...Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesPalla, Gergely ; Derényi, Imre ; Farkas, Illés ; Vicsek, Tamás
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Many complex systems in nature and society can be described in terms of networks capturing the intricate web of connections among the units they are made of. A key question is how to interpret the global organization of such networks as the coexistence of their structural subunits (communities) ...Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesBernal-Mizrachi, Carlos ; Gates, Allison C. ; Weng, Sherry ; Imamura, Takuji ; Knutsen, Russell H. ; DeSantis, Pascual ; Coleman, Trey ; Reid Townsend, R. ; Muglia, Louis J. ; Semenkovich, Clay F.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The observations that atherosclerosis often occurs in non-smokers without elevated levels of low-density lipoprotein cholesterol, and that most atherosclerosis loci so far identified in mice do not affect systemic risk factors associated with atherosclerosis, suggest that as-yet-unidentified ...Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National Licenses
[s.l.] : Macmillian Magazines Ltd. Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Nature 429, 853–857 (2004) The date of acceptance of this Letter was 17 May 2004, and not 5 December 2004 as ...Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesGilbert, M. ; Mitchell, A. ; Bourn, D. ; Mawdsley, J. ; Clifton-Hadley, R. ; Wint, W.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] For 20 years, bovine tuberculosis (BTB) has been spreading in Great Britain (England, Wales and Scotland) and is now endemic in the southwest and parts of central England and in southwest Wales, and occurs sporadically elsewhere. Although its transmission pathways remain poorly understood, the ...Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesKanai, Tsuneto ; Minemoto, Shinichirou ; Sakai, Hirofumi
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] High-order harmonic generation (HHG) from atoms and molecules offers potential application as a coherent ultrashort radiation source in the extreme ultraviolet and soft X-ray regions. In the three-step model of HHG, an electron tunnels out from the atom and may recombine with the parent ion ...Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesKaazik, Peter B. ; Ovtchinnikov, Vladimir M. ; Krasnoshchekov, Dmitry N.
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Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The transition from the Earth's solid inner core to liquid outer core is the location where the inner core grows and from which compositional convection in the outer core originates. Most seismological models of the Earth describe the inner-core boundary as sharp and simple, although ...Type of Medium: Electronic ResourceURL: