Search Results - (Author, Cooperation:Z. Y. Lin)

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  1. 1
    Staff View
    Publication Date:
    2012-09-18
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Biofilms/growth & development ; Candida albicans/cytology/*genetics/*growth & development ; DNA Mutational Analysis ; Gene Deletion ; *Gene Expression Regulation, Fungal ; Hyphae/genetics/growth & development ; Nuclear Proteins/genetics ; Saccharomyces cerevisiae/cytology/*genetics/*growth & development ; Saccharomyces cerevisiae Proteins/genetics ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    S. Gueroussov ; T. Gonatopoulos-Pournatzis ; M. Irimia ; B. Raj ; Z. Y. Lin ; A. C. Gingras ; B. J. Blencowe
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-08-22
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Alternative Splicing ; Animals ; *Biological Evolution ; Brain/*embryology ; Chickens ; Embryonic Stem Cells/metabolism ; Exons/genetics ; HEK293 Cells ; Heterogeneous-Nuclear Ribonucleoproteins/*genetics ; Humans ; Mice ; Neural Stem Cells/metabolism ; Neurogenesis/*genetics ; Polypyrimidine Tract-Binding Protein/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
  4. 4
  5. 5
    Staff View
    ISSN:
    1432-0509
    Keywords:
    Key words: Color Doppler ultrasound—Focal nodular hyperplasia—Central stellate vascular appearance—Hepatic angiography—Spoke wheel sign.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract. Background: We assessed the color Doppler ultrasound (US) findings in focal nodular hyperplasia (FNH). Methods: Seven FNH lesions were imaged with color Doppler US and hepatic angiography. Results: In four lesions, color Doppler demonstrated a central stellate vascular appearance which correlated with central feeding artery with spoke-wheel sign angiographically. Except for one lesion, color Doppler US imaging correlated with angiographic findings. Conclusions: Color Doppler US is capable of demonstrating the typical findings of a central feeding artery and stellate vascular pattern in many cases of FNH.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Chen, J. D. Z. ; Lin, Z. Y. ; Parolisi, S. ; McCallum, R. W.
    Springer
    Published 1995
    Staff View
    ISSN:
    1573-2568
    Keywords:
    cholecystokinin ; gastric myoelectrical activity ; electrogastrography ; gastrointestinal motility ; gastric emptying ; stomach
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract While a number of studies have investigated the effects of cholecystokinin (CCK) on gastrointestinal motility, little is known on the effects of CCK on gastric myoelectrical activity, which regulates gastric motility. The aim of this study was to investigate the effects of intravenous infusion of CCK-8 on gastric myoelectrical activity in normal humans. Gastric myoelectrical activity was measured in 10 healthy subjects with a noninvasive electrogastrographic technique by placing abdominal electrodes on the epigastric area. Two study sessions were performed in each subject on two separate days with double-blinded infusion of either saline or CCK (24 pmol/kg/hr). The procedure for each session was as follows: (A) 30-min baseline fasting electrogastrogram (EGG); (B) start infusion, another 30-min EGG; (C) give meal, 60-min EGG; and (D) stop infusion, another 60-min EGG. The dominant frequency and peak power (amplitude) of the EGG, and the percentage of normal 2–4 cycles/min slow waves during each recording session were computed and compared between placebo and CCK. It was found that normal 3 cpm slow waves were recorded in all EGGs. Infusion of CCK had no effect on the frequency of the gastric slow wave and did not induce gastric dysrhythmias. It was also found that intravenous infusion of CCK significantly decreased the EGG peak power (amplitude) during the first hour after the meal (the infusion was given during this period) in comparison with placebo (P〈0.05). This inhibitory effect on EGG peak power was sustained but not significant during the second postprandial hour (the infusion was not given during this period). It was concluded that intravenous infusion of CCK at a physiological concentration significantly decreased the postprandial EGG amplitude in normal humans, suggesting an inhibitory effect on postprandial gastric motility, but did not change the frequency and regularity of the gastric slow wave.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1573-2568
    Keywords:
    OCTREOTIDE ; ERYTHROMYCIN GASTRIC ; MANOMETRY ; GASTRIC MYOELECTRIC ACTIVITY ; GASTROPARESIS
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Simultaneous recordings of gastric manometry andmyoelectrical activity were made in 10 patients withgastroparesis. Intravenous erythromycin (100 mg) wasadministered in the fasting state for a period of 30 min. Subcutaneous injection of octreotide(100 μg) was administered before one of the fouridentical test meals. It was found that octreotidesignificantly decreased the antral motility index(30-min fasting: 4.51 ± 1.04 vs 1.75 ±0.97, P 〈 0.02; 60-min fed: 5.16 ± 1.44 vs 3.4± 1.41, P 〈 0.05) and the dominant power ofthe EGG (fasting power: 35.19 ± 1.54 vs 30.84± 1.57 dB, P 〈 0.004; postprandial powerincrease: 5.52 ± 1.06 vs 0.27 ± 0.87, P〈 0.001). Erythromycin significantly increased theantral motility index (3.16 ± 0.96 vs 9.5± 0.61, P 〈 0.001) and the dominant power ofthe EGG (28.86 ± 1.57 dB vs 33.55 ± 1.59dB, P 〈 0.005) in the fasting state. An improvement in theregularity of the gastric slow wave was also noted witherythromycin. It was concluded that: (1) the inhibitoryeffect of octreotide on postprandial gastric motility and myoelectrical activity suggests thatcaution should be exercised when octreotide is used inpatients with gastroparesis; and (2) the stimulatoryeffect of erythromycin on gastric myoelectrical activity may enhance gastric motility and gastricemptying in patients with gastroparesis.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses