Search Results - (Author, Cooperation:X. L. Yang)

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  1. 1
    Staff View
    Publication Date:
    2018-05-26
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0066-4804
    Electronic ISSN:
    1098-6596
    Topics:
    Biology
    Medicine
    Published by:
    http://www.asm.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    W. S. Lo ; E. Gardiner ; Z. Xu ; C. F. Lau ; F. Wang ; J. J. Zhou ; J. D. Mendlein ; L. A. Nangle ; K. P. Chiang ; X. L. Yang ; K. F. Au ; W. H. Wong ; M. Guo ; M. Zhang ; P. Schimmel
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-07-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alternative Splicing ; Amino Acyl-tRNA Synthetases/chemistry/genetics/*metabolism ; Catalysis ; *Catalytic Domain ; Humans ; Isoenzymes/chemistry/genetics/metabolism ; Organ Specificity ; Protein Isoforms/chemistry/genetics/metabolism ; Recombinant Proteins/chemistry/genetics/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    R. Ishimura ; G. Nagy ; I. Dotu ; H. Zhou ; X. L. Yang ; P. Schimmel ; S. Senju ; Y. Nishimura ; J. H. Chuang ; S. L. Ackerman
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-07-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Cycle Proteins/genetics/*metabolism ; Cell Nucleus/genetics ; Cerebellum/*metabolism/pathology ; GTP-Binding Proteins/genetics/*metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Microfilament Proteins/genetics/*metabolism ; Neurodegenerative Diseases/*genetics ; Point Mutation ; Protein Biosynthesis/*genetics ; RNA Splice Sites/genetics ; RNA, Transfer, Arg/*genetics ; Ribosomes/*metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2013-11-01
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cercopithecus aethiops ; China ; Chiroptera/*virology ; Disease Reservoirs/virology ; Feces/virology ; Fluorescent Antibody Technique ; Genome, Viral/genetics ; Host Specificity ; Humans ; Molecular Sequence Data ; Pandemics/prevention & control/veterinary ; Peptidyl-Dipeptidase A/genetics/*metabolism ; Real-Time Polymerase Chain Reaction ; Receptors, Virus/genetics/metabolism ; SARS Virus/genetics/*isolation & purification/*metabolism/ultrastructure ; Severe Acute Respiratory Syndrome/prevention & ; control/transmission/veterinary/virology ; Species Specificity ; Spike Glycoprotein, Coronavirus/chemistry/metabolism ; Vero Cells ; Virion/isolation & purification/ultrastructure ; Virus Internalization ; Viverridae/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2016-01-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    X L Yang, Z P Wang, W Zhao, S H Bian, X Y Liu and Y P Liu
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-10-31
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1755-1307
    Electronic ISSN:
    1755-1315
    Topics:
    Geography
    Geosciences
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    M. Naganuma ; S. Sekine ; Y. E. Chong ; M. Guo ; X. L. Yang ; H. Gamper ; Y. M. Hou ; P. Schimmel ; S. Yokoyama
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-06-12
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine Monophosphate/analogs & derivatives/chemistry ; Alanine-tRNA Ligase/*chemistry ; Archaeoglobus fulgidus/*enzymology/*genetics ; *Base Pairing ; Base Sequence ; Catalytic Domain ; Crystallography, X-Ray ; Kinetics ; Models, Molecular ; RNA, Transfer, Ala/*chemistry/*genetics ; Substrate Specificity ; *Transfer RNA Aminoacylation
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    H. Zhou ; L. Sun ; X. L. Yang ; P. Schimmel
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-12-25
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine Triphosphate/chemistry/*metabolism/pharmacology ; Amino Acyl-tRNA Synthetases/antagonists & inhibitors/*chemistry/*metabolism ; Antimalarials/chemistry/pharmacology ; Binding Sites ; Crystallography, X-Ray ; Herbal Medicine ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Medicine, Chinese Traditional ; Models, Molecular ; Piperidines/*chemistry/*metabolism/pharmacology ; Proline/chemistry/metabolism ; Quinazolines/chemistry/pharmacology ; Quinazolinones/*chemistry/*metabolism/pharmacology ; RNA, Transfer/chemistry/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Staff View
    Publication Date:
    2018-03-12
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Electronic structure and strongly correlated systems
    Published by:
    http://www.aps.org/

    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Staff View
    Publication Date:
    2018-06-14
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0022-538X
    Electronic ISSN:
    1098-5514
    Topics:
    Medicine
    Published by:
    http://www.asm.org/

    Latest Papers from Table of Contents or Articles in Press
  12. 12
    Staff View
    Publication Date:
    2018-05-12
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Electronic structure and strongly correlated systems
    Published by:
    http://www.aps.org/

    Latest Papers from Table of Contents or Articles in Press
  13. 13
    Yang, X. L. ; Yang, J. X. ; Jiang, K. Y. ; Chen, G.

    [S.l.] : American Institute of Physics (AIP)
    Published 1999
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A two-phase system of Fe-based nanocrystalline alloys is here investigated. The nanocrystalline Fe69.5Cu0.5Cr4V5Si13B8 alloys, which consist of two magnetic phases: α-FeSi grains and an amorphous matrix, were prepared by annealing the amorphous ribbons. Mössbauer spectroscopy and magnetic measurements at elevated temperatures were carried out. The results show that the exchange coupling interaction exists between grains through the amorphous matrix, and obviously affect the soft magnetic properties of the nanocrystalline alloys. A phenomenological coupling model is applied to estimate the coupling intensity for samples annealed at different temperatures and the data can reasonably explain why the nanocrystalline alloys annealed at 540 °C hold the best soft magnetic properties. © 1999 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.369098

    Articles: DFG German National Licenses
  14. 14
    Chen, G. ; Yang, X. L. ; Zeng, L. ; Yang, J. X. ; Gong, F. F.

    [S.l.] : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Giant magnetoimpedance (GMI) was investigated from room temperature up to 823 K in an Fe-based nanocrystalline Fe73.0Cu1.0Nb2.5V1.0Si13.5B9.0 ribbon. With an increment of the measuring temperature (T), GMI shows notable enhancement followed by a declining dependence, yielding a maximum value around 603 K where the relative GMI is nearly four times that at room temperature. The field at the peak of the GMI vs Hdc curve decreases monotonically with T, but around T=603 K there superimposes a trough-shaped variation. The thermal evolution of the soft magnetic property and magnetic anisotropy is suggested to be responsible for the high-temperature GMI features. Discussion on the intergrain exchange magnetic coupling through the amorphous boundaries in the two-phase Fe-based nanocrystalline alloy is also given. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.373315

    Articles: DFG German National Licenses
  15. 15
    Shul, R. J. ; Passarella, R. ; Yang, X. L. ; Keesee, R. G. ; Castleman, A. W.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1987
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    The rate coefficients for the reactions of Ar+ and Ar+2 with CH4 and CS2 are obtained as a function of energy by using a selected ion flow tube with an electric drift field (SIFT-DRIFT). A diagnostic analysis of the system and technique has been completed and allows rate coefficients to be reported with a high level of confidence. Rate coefficients and product branching ratios are determined for the methane reactions from thermal (room temperature) to center-of-mass kinetic energies of about 0.15 eV and for the carbon disulfide reactions from thermal to about 0.6 eV. The overall rate coefficients for these reactions do not vary a great deal over the investigated energy range. The greatest dependence is found for the slowest reaction Ar+ with CS2, where a minimum in the rate coefficient is observed near 0.15 eV. The behavior of the branching ratios for S+ and CS+2 suggests curve crossings between a repulsive state and the A, B, and C electronic states of CS+2.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.453224

    Articles: DFG German National Licenses
  16. 16
    Deng, Z.-Y. ; Yang, X.-L. ; Gu, S.-W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0038-1098(93)90865-K

    Articles: DFG German National Licenses
  17. 17
    Jiang, J. S. ; Gao, L. ; Yang, X. L. ; Guo, J. K. ; Shen, H. L.
    Springer
    Published 1999
    Staff View
    ISSN:
    1573-4811
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1006639530050

    Articles: DFG German National Licenses
  18. 18
    Zhu, H.-S. ; Yang, X.-L. ; Wang, L.-B. ; Zhao, D.-X. ; Chen, L.
    Springer
    Published 2000
    Staff View
    ISSN:
    1573-6822
    Keywords:
    calcium ; cell cycle ; cell growth ; Ganoderma lucidum ; spores
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract The effects of extracts from Ganoderma lucidum spores on the growth of human cervix uteri tumor HeLa cells as well as on the cell cycle and intracellular calcium level were investigated. Alcohol extracts were prepared from sporoderm-broken and sporoderm-nonbroken spores (termed extract I and extract II) of G. lucidum. Extract I was then subjected to silica gel chromatography to obtain extract III. Cytotoxicity was examined by means of trypan blue exclusion and MTT tests. It was found that extract I and extract III, but not extract II strongly inhibited the growth of HeLa cells, and that extract III was more effective than extract I. Moreover, extract III was shown to be capable of blocking the cell cycle at the transition from G1 to S phase and inducing a marked decrease of intracellular calcium level, determined by flow cytometry and the specific fluorescent calcium probe Fura-2, respectively. These results imply that (1) the breaking of G. lucidum spores improves the release of cytotoxic activity and (2) the effective extract might influence the cell cycle and cellular signal transduction by altering the calcium transport system.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1007663006548

    Articles: DFG German National Licenses
  19. 19
    Yang, X. L. ; Wu, X. R.
    Springer
    Published 1988
    Staff View
    ISSN:
    1573-7195
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Resumé On a administré à 8 femmes enceintes, à moins de 49 jours d'aménorrhée, 600 mg de RU 486 par voie orale en une seule dose et, 48 heures après, 1 mg de PG-05 sous forme de suppositoire vaginal. Pendant toute la durée du traitement, on a déterminé par RIA, 1a β-hcg (gonadotrophine chorionique humaine), la progestérone, l'estradiol-17β et le PGFM (13,14-dihydro-15-céto-PGF2α) plasmatiques. Dans les 8 cas, les niveaux de β-hCG et de progestérone ont baissé dès l'apparition des règles, qui ont commencé en moyenne 39 heures après l'administration du RU486. Chez 7 femmes ayant eu un avortement complet, E2 a baissé après 72 heures et PGFM a augmenté deux fois en 48 heures. En comparant les résultats des avortements complets avec ceux obtenus chez la seule femme dont l'avortement était incomplet, ces derniers ont fait apparaître des concentrations de E2 beaucoup plus fortes et de PFGM beaucoup plus faibles. Ces résultats laissent penser que le lieu d'action principal du RU486 se trouve probablement sur la membrane caduque en raison des propriétés antagonistes du RU486 à la progestérone, ce qui entraîne alors la chute de β-hCG, de la progestérone ainsi que de E2. Ils indiquent également que le RU486 favorise sans doute la production de prostaglandines endogènes, ce qui peut s'expliquer par les changements du tissu décidual induits par le RU486.
    Abstract:
    Resumen A 8 mujeres embarazadas (menos de 49 días de amenorrea) se les administró oralmente en dosis única, 600 mg de RU486 y 48 horas después, 1 mg de PG-05 en forma de supositorio vaginal. El plasma β-hCG, Progesterona, 17β-estradiol y PGFM (13,14-dihidro-15-keto-PGF2α) fueron determinados por RIA durante el tratamiento. En los 8 casos, los niveles de β-hCG progesterona descendieron siguiendo el comienzo del sangrado que ocurrió en un término medio de 39 horas después que RU486 fuera administrado. En 7 mujeres que experimentaron un aborto completo, E2 disminutó después de 72 horas y PGFM aumentó dos veces en 48 horas. En comparación con estos resultados, las concentraciones de E2 en un aborto incompleto fueron mucho más altas mientras que los de PGFM fueron mucho más bajas. Los resultados sugieren que el sitio primordial de acción de RU486 posiblemente sea el tejido decidual debido a la propiedad antiprogesterona de RU486 que a su vez produce la caída de β-hCG, de progesterona, así como de E2. Esto también indica que RU486 puede facilitar la producción de prostaglandinas endógenas lo que estaría explicado por los cambios inducidos en el tejido decidual por RU486.
    Notes:
    Abstract 8 pregnant women (below 49 days of amenorrhea) were administered 600 mg RU486 orally in a single dosage, and 1 mg PG-05 as a vaginal suppository 48 h afterwards. The plasma β-hCG, progesterone, 17β-estradiol and PGFM (13,14-dihydro-15-keto-PGF2α) were determined by RIAs throughout the treatment. In all 8 cases, β-hCG and progesterone levels fell following the onset of bleeding, which happened in a mean time of 39 h after RU486 administration. In 7 women who experienced complete abortion, E2 dropped after 72 h and PGFM increased two-fold within 48 h. In comparison with these results of complete abortion, the concentrations of E2 in the woman experiencing incomplete abortion were much higher, while those of PGFM were much lower. The results suggest that the primary action site of RU486 is probably in the decidual tissue, because of the progesterone-antagonistic property of RU486, which in turn leads to the drop in β-hCG, progesterone and E2. It also indicates that RU486 may facilitate the production of endogenous prostaglandins, which can be explained by the changes of decidual tissue induced by RU486.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01849274

    Articles: DFG German National Licenses
  20. 20
    Yang, X. -L. ; Wu, X. -R.
    Springer
    Published 1989
    Staff View
    ISSN:
    1573-7195
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Resumé On a administré à 6 femmes enceintes (ayant moins de 49 jours d'aménorrhée) qui désiraient interrompre leur grossesse, par voie orale en une seule prise 600 mg de RU486 et, 48 heures après, un ovule vaginal de 1 mg de PG-05 ou de ONO-802. On a contrôlé les niveaux du cortisol, de la corticostérone, de l'aldostérone et de l'ACTH plasmatiques à -0, 5, 1, 2, 4, 10, 24, 48 et 72 heures, ainsi que lors de la première visite de suivi à 8 jours. Le niveau de cortisol s'était élevé pendant le traitment mais, au moment de la première visite de suivi, les valeurs étaient retombées au niveau relevé avant le traiment. Des changements analogues à ceux du cortisol ont été constatés pour la corticostérone. L'ACTH s'était également élevée pendant le deux premières heures pour revenir à son niveau de base après 48 heures. Aucun changement notable de l'aldostérone n'a été retrouvé pendant le traitement. Ces résultats suggèrent qu'une compensation de la fonction adrénalo-pituitaire s'est produite pendant le traitement, qui est probablement associée à une diminution du mécanisme de contre-réaction du cortisol due à l'action antiglycocorticostéroidale du RU486 au niveau de l'hypothalamus.
    Abstract:
    Resumen Seis mujeres embarazadas (menos de 49 días de amenorrea) recibieron 600 mg de RU486 en dosis única por vía oral y 1 mg de PG-05 u ONO-802 en forma de supositorio vaginal 48 horas más tarde. El cortisol, costicosterona, aldosterona y ACTH plasmáticos fueron controlados a las -0.5, 1, 2, 4, 10, 24, 48 y 72 horas así como durante la primer visita de seguimiento al octavo día. El cortisol aumentó durante el tratamiento y los valores volvieron a los niveles de antes del tratamiento hacia la primer visita de seguimiento. Los cambios de corticosterona fueron similares a los del cortisol. El ACTH también aumentó dentro de las dos primeras horas y volvió al nivel basal a las 48 horas. No hubo cambio notable en la aldosterona durante el tratamiento. Los resultados sugieren que una compensación de la función pituitario-adrenal ocurrió durante el tratamiento la que probablement está asociada con una disminución en el mecanismo de retroalimentación de cortisol debido a la actividad antigluco-corticoesteroidea del RU486 a nivel hipotalámico.
    Notes:
    Abstract Six pregnant women (below 49 days of amenorrhea) desiring pregnancy termination received 600 mg RU486 orally in a single dosage and 1 mg PG-05 or ONO-802 as vaginal suppository 48 h afterward. Plasma cortisol, corticosterone, aldosterone and ACTH were monitored at -0.5, 1, 2, 4, 10, 24, 48, 72 h as well as during the first follow-up visit at the 8th day. Cortisol increased during the treatment and the values returned to the pretreatment level by the first follow-up visit. The changes of corticosterone were similar to those of cortisol. ACTH was also elevated within first 2 h and returned to the basal level at 48 h. There was no notable change in aldosterone during the treatment. The results suggest that a compensation of the pituitary-adrenal function occurred during the treatment, which is probably associated with a decreased negative feedback mechanism of cortisol due to the antiglucocorticosteroid activity of RU486 at the hypothalamus level.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02340131

    Articles: DFG German National Licenses