Search Results - (Author, Cooperation:W. Xue)

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  1. 1
    Jiang W, Xue J, Yu W.
    Oxford University Press
    Published 2018
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Oxford University Press
    Print ISSN:
    1467-5463
    Electronic ISSN:
    1477-4054
    Topics:
    Biology
    Computer Science
    Published by:
    http://global.oup.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Jiang, J., Cao, J., Wang, W., Xue, J.
    Royal Society
    Published 2018
    Staff View
    Publication Date:
    2018-06-07
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    materials science, nanotechnology
    Published by:
    http://royalsocietypublishing.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-12-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Botany, Molecular Biology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2012-10-02
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Asian Continental Ancestry Group ; Butyrates/metabolism ; China/ethnology ; Cohort Studies ; Diabetes Mellitus, Type ; 2/classification/complications/*microbiology/physiopathology ; Feces/microbiology ; Genetic Linkage/genetics ; Genetic Markers ; Genome-Wide Association Study/*methods ; High-Throughput Nucleotide Sequencing ; Humans ; Intestines/*microbiology ; Metabolic Networks and Pathways/genetics ; Metagenome/*genetics ; Metagenomics/*methods ; Opportunistic Infections/complications/microbiology ; Reference Standards ; Sulfates/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2014-10-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenocarcinoma/*genetics/pathology ; Animals ; *Caspase 9 ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Disease Models, Animal ; Genes, Tumor Suppressor ; *Genetic Engineering ; Genome/*genetics ; Humans ; Lentivirus/genetics ; Lung Neoplasms/*genetics/pathology ; Mice ; Mice, Inbred C57BL ; Models, Genetic ; Mutation/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2014-08-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Base Sequence ; *CRISPR-Cas Systems ; Cell Transformation, Neoplastic/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Female ; *Genes, Tumor Suppressor ; Genes, p53/genetics ; Genetic Engineering/*methods ; Hepatocytes/metabolism/pathology ; Lipid Metabolism ; Liver/cytology/*metabolism/pathology ; Liver Neoplasms/genetics/metabolism/pathology ; Mice ; Molecular Sequence Data ; Mutagenesis/*genetics ; Mutation/*genetics ; Oncogenes/*genetics ; PTEN Phosphohydrolase/genetics ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; beta Catenin/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2018-11-06
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1757-8981
    Electronic ISSN:
    1757-899X
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    F. Xue, W. Gao, Y. Duan, R. Zheng and Y. Hu
    Institute of Physics Publishing (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-02-24
    Publisher:
    Institute of Physics Publishing (IOP)
    Electronic ISSN:
    1748-0221
    Topics:
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    W X Xu, F Xue, W H Wang, S Q Yuan and Z M Ji
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-07-31
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1755-1307
    Electronic ISSN:
    1755-1315
    Topics:
    Geography
    Geosciences
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Xue, W C ; Feng, H C ; Chan, K Y K ; Chiu, P M ; Ngan, H Y S ; Khoo, U S ; Tsao, S W ; Chan, K W ; Cheung, A N Y

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Aims : To assess the expression of Id proteins in trophoblastic tissues and to correlate this with clinical parameters, proliferative and apoptotic indices as well as to related oncogene expression.Methods and results : Immunohistochemistry for Id1, Id2, Id3 and Id4 was performed on 83 trophoblastic tissues including 17 normal first-trimester placentas, seven term placentas, 47 hydatidiform moles (HM), and 12 spontaneous miscarriages. The four Id proteins were predominantly expressed in the villous and implantation site intermediate trophoblast. Expression of Id1 in HM was significantly higher than that in normal placenta (P = 0.0006) and spontaneous miscarriage (P = 0.0001) but did not correlate with subsequent development of gestational trophoblastic neoplasia (GTN). Id1 expression correlated with the proliferation index as assessed by MCM7 (P = 0.003) and Ki67 (P = 0.017) and with the apoptotic activity assessed by TUNEL (P = 0.001) and M30 CytoDeath antibody (P = 0.013). Moreover, the expression of Id1 correlated with the expression of p53 (P = 0.004), p21WAF1/CIP1 (P = 0.003) but not with p16 (P = 0.107).Conclusions : Id proteins may play a role in the regulation of proliferative and apoptotic activity in trophoblastic tissue and are potentially useful in differentiating molar and non-molar gestation, but are not helpful in predicting GTN.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2559.2005.02190.x

    Articles: DFG German National Licenses
  11. 11
    Xue, W C ; Khoo, U S ; Ngan, H Y S ; Chan, K Y K ; Chiu, P M ; Tsao, S W ; Cheung, A N Y

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Aims:  To assess the proliferative activity of gestational trophoblastic disease (GTD) using one of the novel proliferation markers (MCM7) and to determine its prognostic value in hydatidiform mole (HM).Methods and results:  Immunohistochemical staining for MCM7 was performed on 122 samples of paraffin-embedded trophoblastic tissues including 22 normal first-trimester placentas, 12 term placentas, 12 spontaneous miscarriages (SM), 21 partial moles (PM), 44 complete hydatidiform moles (CM), and 11 choriocarcinomas (CCA). The correlations between the proliferative indices assessed by MCM7, proliferating cell nuclear antigen (PCNA) and Ki67 (MIB1) immunoreactivity as well as clinical progress were assessed. MCM7 immunoreactivity was found predominantly in the nuclei of cytotrophoblast and intermediate trophoblast and decreased with placental maturation. MCM7 expression was highest in CCA, followed by CM, PM, normal first-trimester placenta, SM and term placenta. MCM7 index was significantly higher in PM and CM than in SM (P = 0.007, P 〈 0.001) but not between PM and CM themselves (P = 0.560). Eighteen of the 65 patients with HM developed persistent trophoblastic disease (PTD) requiring chemotherapy. There was no significant difference in MCM7 indices between the patients who developed PTD and those who did not (P = 0.312). MCM7 indices correlated well with Ki67 (P = 0.002) but not with PCNA (P = 0.054) indices. MCM7 indices demonstrated less variability than PCNA and Ki67 and may be a better proliferation marker than the latter two.Conclusions:  We conclude that MCM7 is useful in differentiating molar and non-molar gestations but is not helpful in discriminating PM from CM or in predicting PTD.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2559.2003.01728.x

    Articles: DFG German National Licenses
  12. 12
    Xue, W. ; Carlson, R.M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0021-9673
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0021-9673(88)90008-8

    Articles: DFG German National Licenses
  13. 13
    Kindzelskii, A.L. ; Xue, W. ; Todd, R.F. ; Petty, H.R.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    1047-8477
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/jsbi.1994.1053

    Articles: DFG German National Licenses
  14. 14
    Denton, F.T. ; Scarth, W.M. ; Xue, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    1059-0560
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/1059-0560(93)90028-O

    Articles: DFG German National Licenses
  15. 15
    Curran, D.P. ; Hongyan, Q. ; Porter, N.A. ; Qi, S. ; Wen-Xue, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-4039
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0040-4039(93)88066-R

    Articles: DFG German National Licenses
  16. 16
    Li, S S ; Xue, W C ; Khoo, U S ; Ngan, H Y S ; Chan, K Y K ; Tam, I Y S ; Chiu, P M ; Ip, P P C ; Tam, K F ; Cheung, A N Y

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Aims : To assess, in tissue microarray (TMA), the proliferative activity of endometrial carcinoma using one of the minichromosome maintenance (MCM) proteins (MCM7), and to explore its potential value for prognosis. MCM proteins are essential for eukaryotic DNA replication and have recently been used to define the proliferative compartments in human tissues.Methods and results : Immunohistochemistry for MCM7 and Ki67 was performed on TMAs constructed from 212 cases of endometrial carcinoma. MCM7 and Ki67 expression was quantified according to the extent of nuclear staining. An analysis was carried out of the association between MCM7 expression and that of Ki67 and the clinicopathological characteristics of endometrial carcinoma. MCM7 and Ki67 immunoreactivity was clearly evident in the nuclei of tumour cells. MCM7 and Ki67 labelling indices in endometrial carcinomas correlated with each other (P 〈 0.001). A significant correlation existed between the MCM7 labelling index and histological grade (P = 0.008) and patients' age at diagnosis (P 〈 0.001). Well-differentiated carcinomas and younger patients had a lower MCM7 index. Poor survival was observed in patients with endometrial carcinoma with a high MCM7 index (P = 0.03) and MCM7 was found to be an independent prognostic factor by multivariate analysis (P = 0.04). The Ki67 labelling index correlated with histological grade (P = 0.01) but had no significant prognostic impact (P = 0.50).Conclusions : In this TMA study on endometrial carcinoma, MCM7 was found to be a more reliable and useful marker than Ki67 in assessing tumour proliferation and in the prognosis of patients.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2559.2005.02069.x

    Articles: DFG German National Licenses
  17. 17
    Xue, W. M. ; Huang, H. C. ; Huang, D. T. ; Hon, Y. C.
    Springer
    Published 1993
    Staff View
    ISSN:
    0894-9166
    Keywords:
    finite element grid ; complex connected domain
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Notes:
    Abstract An automated quasi three-dimensional finite element grid generation method is presented for particular three-dimensional complex connected domain, across which some are simply connected two-dimensional.regions and some are multiply connected two-dimensional regions. A subdivision algorithm based on the variational principle has been developed to ascertain the smoothness and orthogonality of the generated grid in any cross sections. Smooth transition between the simply and multiply connected regions is maintained. For illustration, the method is applied to generate a finite element three-dimensional grid for human above knee stump.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02207814

    Articles: DFG German National Licenses
  18. 18
    Roh, J. ; Schamer, M. ; Reilman, R. ; Xue, W. ; Warshawsky, D. ; Talaska, G.
    Springer
    Published 1993
    Staff View
    ISSN:
    1432-1246
    Keywords:
    Dibenz[a,j]acridine ; DNA adduct ; 32P-postlabeling assay ; trans-DBA-3,4-dihydrodiol
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary N-Heterocyclic aromatics (NHA) are widely occurring environmental pollutants formed during the pyrolysis of nitrogen-containing organic chemicals. NHA are found in significant amounts in tobacco condensates, synthetic fuels, gasoline engine exhaust, and effluents from the heating of coal. Dibenz[a,j]acridine (DBA) is an example of NHA. The potency of many carcinogenic compounds is related, at least in part, to the efficiency of their biological activation. We undertook studies to determine which initial metabolites of DBA lead to the formation of high levels of carcinogen-DNA adducts in vivo. DBA and its metabolites, traps-DBA-1,2-dihydrodiol (DBA-1,2-DHD), trans-DBA-3,4-dihydrodiol (DBA-3,4-DHD), and trans-DBA-5,6-dihydrodiol (DBA-5,6-DHD), were applied to the skin of mice. DNA as isolated using enzyme-solvent extraction method. DNA was 32p-postlabeled under conditions of limiting [32P]ATP. In skin, DBA produced two distinct adducts. The same two adducts were seen when DBA-3,4-DHD was applied In addition the total adduct level elicited by DBA-3,4-DHD was higher than that of parent compound. Two adducts were seen when DBA-5,6DHD was applied, but these were very different from adducts seen with DBA. These results suggested that activation of DBA to DNA-binding compounds in skin includes initial formation of DBA-3,4-DHD. The data support development of biomarkers for the exposure and effect of this compound, and also suggest that specific metabolic susceptibility markers might be able to predict populations at increased risk.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00381316

    Articles: DFG German National Licenses
  19. 19
    Zhang, Y.-g. ; Zhang, P. ; Xue, W.-m.
    Springer
    Published 1994
    Staff View
    ISSN:
    1432-0924
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract This paper deals with the limit analysis of rigid perefectly plastic body under the combined action of initial constant loadings and proportional loadings. Using the von Mises yielding condition and the finite element technique, we present an efficient algorithm based on the mathematical programming formula of the classical kinematic theorem of plasticity theory. This algorithm includes an iterative procedure which produces a monotonically decrescent sequence converging to an upper bound of the real limit load. The results of some numerical examples are presented and show the stable convergency of the new algorithm.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00370074

    Articles: DFG German National Licenses
  20. 20
    Xue, W. ; Atluri, S. N.
    Springer
    Published 1999
    Staff View
    ISSN:
    1432-0924
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Summary In this paper the general hybrid-mixed finite element methods are investigated systematically in a framework of multi-field variational equations. The commonly accepted concept “saddle point problem” is argued in this paper. The existence, uniqueness, convergence, and stability properties of the solutions are proved undertaking the assumptions of Ker*-ellipticity and nested BB-conditions. The relation between discrete BB-condition and smallest singular value, and a so-called singular value principle are proposed for the practical applications using hybrid-mixed finite element methods.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004660050379

    Articles: DFG German National Licenses