Search Results - (Author, Cooperation:W. M. Lin)
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1Latest Papers from Table of Contents or Articles in PressD. Bozyigit ; N. Yazdani ; M. Yarema ; O. Yarema ; W. M. Lin ; S. Volk ; K. Vuttivorakulchai ; M. Luisier ; F. Juranyi ; V. Wood
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressC. J. Ceol ; Y. Houvras ; J. Jane-Valbuena ; S. Bilodeau ; D. A. Orlando ; V. Battisti ; L. Fritsch ; W. M. Lin ; T. J. Hollmann ; F. Ferre ; C. Bourque ; C. J. Burke ; L. Turner ; A. Uong ; L. A. Johnson ; R. Beroukhim ; C. H. Mermel ; M. Loda ; S. Ait-Si-Ali ; L. A. Garraway ; R. A. Young ; L. I. Zon
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Age of Onset ; Amino Acid Substitution ; Animals ; Animals, Genetically Modified ; Cell Transformation, Neoplastic/genetics ; Chromatin Immunoprecipitation ; Chromosomes, Human, Pair 1/genetics ; DNA Copy Number Variations/*genetics ; Disease Models, Animal ; Gene Amplification/*genetics ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Homeobox/genetics ; Histone-Lysine N-Methyltransferase/*genetics/metabolism ; Humans ; Melanocytes/cytology/enzymology/metabolism/pathology ; Melanoma/enzymology/*genetics/*pathology ; Nevus/enzymology ; Oncogenes/genetics ; Protein Methyltransferases/*genetics/*metabolism ; Proto-Oncogene Proteins B-raf/chemistry/genetics/metabolism ; Zebrafish/geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressZ. Q. Liu; J. H. Liu; M. D. Biegalski; J.-M. Hu; S. L. Shang; Y. Ji; J. M. Wang; S. L. Hsu; A. T. Wong; M. J. Cordill; B. Gludovatz; C. Marker; H. Yan; Z. X. Feng; L. You; M. W. Lin; T. Z. Ward; Z. K. Liu; C. B. Jiang; L. Q. Chen; R. O. Ritchie; H. M. Christen; R. Ramesh
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-01-04Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
4Articles: DFG German National LicensesYu, C. -L. ; Liu, C. -L. ; Tsai, C. -Y. ; Sun, K. -H. ; Liao, T. -S. ; Lin, W. -M. ; Chen, H. -L. ; Yu, H. -S.
Springer
Published 1993Staff ViewISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Prostaglandin E2 (PGE2) at concentrations more than 1×10−8 M markedly suppressed the cell proliferation and release of soluble molecules of interleukin-2 receptor (sIL-2R), CD4 (sCD4) and CD8 (sCD8) from phytohemagglutinin (PHA)-stimulated normal human mononuclear cells (MNC) in a dose-related manner. To further elucidate the subcellular mechanism of the inhibitory effect of PGE2 on PHA-stimulated MNC, intracellular concentration of glutathione (GSH) in PHA-stimulated MNC was sequentially measured from day 1 to day 3 by enzymic method. Furthermore, the effect of PGE2 on nuclear DNA including DNA strand breaks in alkali treatment and DNA fragmentation (apoptosis) of PHA-stimulated MNC were also measured. We found intracellular GSH levels were significantly decreased in the early stage of lymphocyte activation (day 1), but no evidence of increased DNA stand breaks or apoptotic process appeared in 3-day culture. In addition, butathione sulfoximine (a specific GSH inhibitor) and dibutyryl cyclic AMP also exhibited both proliferation inhibition and GSH-decreasing effect on PHA-stimulated MNC as well as PGE2. These results suggest that the immunosupressive effect of PGE2 is mediated by the decreased generation of intracellular GSH, but not by the increased DNA strand breaks or apoptotic mechanism in the cells.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1588-2837Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Abstract Добавление малых количеств меди к никелю Ренея увеличивает его активность в гидрогенизации кротонового альдегида и его селективность в гидрогенизации связи C=O. Повышенные количества приводят к повышенной селективности, но к пониженной активности. Для обьяснения этого был использован подход химической координации на катализаторе.Notes: Abstract Addition of small amounts of copper to Raney Ni increases its activity for hydrogenation of crotonaldehyde and its selectivity for C=O bond hydrogenation. Higher amounts lead to higher selectivity but lower activity. The coordination chemical approach to catalysis was used to explain this result.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1588-2837Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Abstract Исследованы активность и селективность медно-железных катализаторов синтеза легких спиртов из моноксида углерода и водорода. Определены благоприятное соотношение меди к железу и оптимальный химический состав катализатора.Notes: Abstract The activity and selectivity of copper-iron catalysts for the synthesis of light alcohols from carbon monoxide and hydrogen were studied. The suitable ratio of copper to iron and optimal chemical composition of the catalyst were determined.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1588-2837Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Abstract Распределение компонентов в катализаторе HG-1, промотированном окисями редкоземельных металлов (успешно разработанный авторами) и используемом в синтезе аммония, определяли на основе электронной микропробной фотографии. Объяснено влияние примесей на активность, а также исключительно большое время жизни катализатора.Notes: Abstract The distribution of components in the HG-1 ammonia catalyst promoted by rare earth oxide (successfully developed by the authors) was analyzed by electron microprobe photography. The results enable us to explain the effect of additives upon the activity as well as the remarkably high lifetime of catalyst.Type of Medium: Electronic ResourceURL: