Search Results - (Author, Cooperation:T. Gruber)

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  1. 1
    Staff View
    Publication Date:
    2014-02-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptor Proteins, Signal Transducing/deficiency/genetics/*metabolism ; Animals ; Anticoagulants/pharmacology/therapeutic use ; Female ; Killer Cells, Natural/drug effects/*immunology/metabolism ; Male ; Mammary Neoplasms, Experimental/drug therapy/genetics/immunology/*pathology ; Melanoma, Experimental/drug therapy/genetics/immunology/*pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasm Metastasis/drug therapy/*immunology/prevention & control ; Proto-Oncogene Proteins/antagonists & inhibitors/metabolism ; Proto-Oncogene Proteins c-cbl/deficiency/genetics/*metabolism ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors/*metabolism ; Ubiquitin-Protein Ligases/deficiency/genetics/*metabolism ; Ubiquitination ; Warfarin/pharmacology/therapeutic use
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
    S. Chakraborty ; T. Gruber ; C. E. Barry, 3rd ; H. I. Boshoff ; K. Y. Rhee
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-11-03
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Aminosalicylic Acid/*metabolism/pharmacology ; Antitubercular Agents/*metabolism/pharmacology ; Dihydropteroate Synthase/antagonists & inhibitors/*metabolism ; Folic Acid/*metabolism ; Molecular Mimicry ; Mycobacterium tuberculosis/drug effects/*metabolism ; Prodrugs/*metabolism/pharmacology ; Substrate Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-10-13
    Publisher:
    Institute of Physics (IOP)
    Electronic ISSN:
    1367-2630
    Topics:
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-05-24
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    behaviour, cognition
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
  7. 7
    Malinowski, P. ; Gruber, T. ; Hillyard, S. A. ; Müller, M. M.

    [s.l.] : Macmillian Magazines Ltd.
    Published 2003
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] By voluntarily directing attention to a specific region of a visual scene, we can improve our perception of stimuli at that location. This ability to focus attention upon specific zones of the visual field has been described metaphorically as a moveable spotlight or zoom lens that facilitates ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Matolcsi, T. ; Gruber, T.
    Springer
    Published 1996
    Staff View
    ISSN:
    1572-9575
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Spacetime structures defined in the language of manifolds admit an absolute formulation, i.e., a formulation which does not refer to observers (reference frames). We consider an affine structure for Galilean spacetime. As an application the Chapman-Enskog iteration for the solution of the Boltzmann equation is given in an absolute form. As a consequence, the second approximations of the stress tensor and the heat flux are obtained in a form independent of observers, which throws new light on material frame indifference.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Gruber, T. M. ; Bryant, D. A.
    Springer
    Published 1998
    Staff View
    ISSN:
    1432-072X
    Keywords:
    Key wordsSynechococcus sp. PCC 7002 ; Cyanobacterium ; σ-Factor ; RNA polymerase ; RpoS ; DpsA ; PexB ; Stationary phase
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The sigD and sigE genes, which encode two alternative σ-factors from the unicellular marine cyanobacterium Synechococcus sp. PCC 7002, were cloned and characterized. Strains in which the sigD and sigE genes were insertionally inactivated were viable under standard laboratory conditions, indicating that SigD and SigE are group 2 σ-factors. When stationary-phase cells were diluted into fresh growth medium, it was observed that the sigE mutant strain required longer times to re-establish exponential growth than the wild-type strain. By monitoring the growth rates in such dilution experiments, it was observed that the lag times for the mutant strain became progressively longer as the original cultures progressed towards stationary phase. Transcripts for the sigE gene initially increased and subsequently decreased as cells grew further into stationary phase. It was determined that a functional SigE protein is required for the expression of the starvation-induced protein DpsA/PexB. The results suggest that SigE is involved in the transcription of genes specifically expressed in the post-exponential phase.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Gruber, T. M. ; Bryant, D. A.
    Springer
    Published 1998
    Staff View
    ISSN:
    1432-072X
    Keywords:
    Key words Chloroflexus aurantiacus ; Chlorobium tepidum ; Green non-sulfur bacteria ; Green sulfur ; bacteria ; Sigma factor ; RNA polymerase ; Phylogenetic studies
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The group 1 and group 2 σ70-type sigma factors of the green sulfur bacterium Chlorobium tepidum and of the green nonsulfur bacterium Chloroflexus aurantiacus were cloned and characterized. Cb. tepidum was found to contain one σ70-type sigma factor; the expression of the gene was analyzed by Northern blot hybridization and primer-extension mapping. Cf. aurantiacus has genes encoding four sigma factors of groups 1 and 2. The expression of these genes was examined in cells grown aerobically and anaerobically. The sigC gene was expressed at approximately equal levels under both conditions, resulting in its designation as the group 1 sigma factor of this organism. The only other detectable transcripts arose from the sigB gene, which was expressed at higher levels during aerobic growth. A phylogenetic tree was obtained using the group 1 sigma factors of Cb. tepidum, Cf. aurantiacus, and diverse eubacteria as the molecular marker. The resulting phylogenetic tree shows that Cb. tepidum and Cf. aurantiacus are related to each other and to the cyanobacteria. The relationship of the group 2 sigma factors of Cf. aurantiacus and the cyanobacteria was more specifically examined phylogenetically. The group 2 sigma factors of Cf. aurantiacus probably arose by gene duplication events after the split of the green nonsulfur bacteria from other photosynthetic eubacteria.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses