Search Results - (Author, Cooperation:S. Horvath)
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1I. Voineagu ; X. Wang ; P. Johnston ; J. K. Lowe ; Y. Tian ; S. Horvath ; J. Mill ; R. M. Cantor ; B. J. Blencowe ; D. H. Geschwind
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-05-27Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alternative Splicing/genetics ; Autistic Disorder/*genetics/*pathology/physiopathology ; Brain/*metabolism/*pathology/physiopathology ; Case-Control Studies ; Exons/genetics ; Frontal Lobe/metabolism/pathology/physiopathology ; *Gene Expression Profiling ; Gene Expression Regulation/*genetics ; Genome-Wide Association Study ; Humans ; Oligonucleotide Array Sequence Analysis ; RNA-Binding Proteins/genetics ; Temporal Lobe/metabolism/pathology/physiopathology ; Transcription, Genetic/geneticsPublished by: -
2M. J. Hawrylycz ; E. S. Lein ; A. L. Guillozet-Bongaarts ; E. H. Shen ; L. Ng ; J. A. Miller ; L. N. van de Lagemaat ; K. A. Smith ; A. Ebbert ; Z. L. Riley ; C. Abajian ; C. F. Beckmann ; A. Bernard ; D. Bertagnolli ; A. F. Boe ; P. M. Cartagena ; M. M. Chakravarty ; M. Chapin ; J. Chong ; R. A. Dalley ; B. D. Daly ; C. Dang ; S. Datta ; N. Dee ; T. A. Dolbeare ; V. Faber ; D. Feng ; D. R. Fowler ; J. Goldy ; B. W. Gregor ; Z. Haradon ; D. R. Haynor ; J. G. Hohmann ; S. Horvath ; R. E. Howard ; A. Jeromin ; J. M. Jochim ; M. Kinnunen ; C. Lau ; E. T. Lazarz ; C. Lee ; T. A. Lemon ; L. Li ; Y. Li ; J. A. Morris ; C. C. Overly ; P. D. Parker ; S. E. Parry ; M. Reding ; J. J. Royall ; J. Schulkin ; P. A. Sequeira ; C. R. Slaughterbeck ; S. C. Smith ; A. J. Sodt ; S. M. Sunkin ; B. E. Swanson ; M. P. Vawter ; D. Williams ; P. Wohnoutka ; H. R. Zielke ; D. H. Geschwind ; P. R. Hof ; S. M. Smith ; C. Koch ; S. G. Grant ; A. R. Jones
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; *Anatomy, Artistic ; Animals ; *Atlases as Topic ; Brain/*anatomy & histology/cytology/*metabolism ; Calbindins ; Databases, Genetic ; Dopamine/metabolism ; *Gene Expression Profiling ; Health ; Hippocampus/cytology/metabolism ; Humans ; In Situ Hybridization ; Internet ; Macaca mulatta/anatomy & histology/genetics ; Male ; Mice ; Neocortex/anatomy & histology/cytology/metabolism ; Oligonucleotide Array Sequence Analysis ; Post-Synaptic Density/genetics ; RNA, Messenger/analysis/genetics ; S100 Calcium Binding Protein G/genetics ; Species Specificity ; Transcriptome/*geneticsPublished by: -
3Z. Xue ; K. Huang ; C. Cai ; L. Cai ; C. Y. Jiang ; Y. Feng ; Z. Liu ; Q. Zeng ; L. Cheng ; Y. E. Sun ; J. Y. Liu ; S. Horvath ; G. Fan
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Blastocyst/cytology/metabolism ; Cell Cycle/genetics ; Embryo, Mammalian/cytology/*embryology/*metabolism ; Embryonic Development/*genetics ; Gene Expression Profiling ; *Gene Expression Regulation, Developmental ; Humans ; Mice ; Morula/cytology/metabolism ; Oocytes/cytology/metabolism ; *Sequence Analysis, RNA ; *Single-Cell AnalysisPublished by: -
4Staff View
Publication Date: 2018-02-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: GeneticsPublished by: -
5Milam, A. A. V., Bartleson, J. M., Donermeyer, D. L., Horvath, S., Durai, V., Raju, S., Yu, H., Redmann, V., Zinselmeyer, B., White, J. M., Murphy, K. M., Allen, P. M.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-05-08Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
6Staff View
ISSN: 1469-8986Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: The purpose of this review was to integrate recent evidence supporting the reliability of thoracic impedance plethysmography as an estimator of cardiodynamic function. Reports regarding the development of the method for NASA, and numerous investigations comparing impedance cardiography to indicator dilution and other methods were discussed. It was concluded that impedance cardiography provides a reliable intra-subject estimation of relative changes in stroke volume and cardiac output. However, the reliability of the technique was found to depend greatly upon its use within a limited range of applications. Myocardial contractility and cardiopathology were also considered.Type of Medium: Electronic ResourceURL: -
7Korytnyk, W. ; Angelino, N. ; Dodson-Simmons, O. ; Hanchak, M. ; Madson, M. ; Valentekovic-Horvath, S.
Amsterdam : ElsevierStaff ViewISSN: 0008-6215Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0008-6215Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0550-3213Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0920-9964Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0196-9781Keywords: GRF-TH coexistence ; Growth hormone-releasing hormone ; In situ hybridization histochemistry ; Paraventricular nucleus ; Tyrosine hydroxylaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
13Drinkwater, B. L. ; Kupprat, I. C. ; Denton, J. E. ; Horvath, S. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1977Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Zusammenfassung Die Untersuchungsergebnisse stützen die Vorstellung, dass die gute Wirkung der prophylaktischen Anwendung von Pentaerythritol-tetranitrat bei Patienten mit Coronarinsuffizienz auf Abnahme der Herztätigkeit und Zunahme der Herzmuskelleistung, nicht aber auf eine Zunahme des Coronarkreislaufes zurückzuführen ist.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Zusammenfassung Mit Hilfe von extrahierter DNS wurde der genetische «Marker» der Phagenresistenz auf phagensensible Bakterien übertragen.Type of Medium: Electronic ResourceURL: -
16Raven, P. B. ; Drinkwater, B. L. ; Horvath, S. M. ; Ruhling, R. O. ; Gliner, J. A. ; Sutton, J. C. ; Bolduan, N. W.
Springer
Published 1974Staff ViewISSN: 1432-1254Source: Springer Online Journal Archives 1860-2000Topics: GeographyPhysicsNotes: Abstract Metabolic, body temperature, and cardiorespiratory responses of 16 healthy middle-aged (40–57 years) men, 9 nonsmokers and 7 smokers, were obtained during tests of maximal aerobic power at ambient environmental temperatures of 25 ± 0.5 and 35 ± 0.5°C and 20% relative humidity under four conditions: (a) filtered air, FA; (b) 50 ppm carbon monoxide in filtered air, CO; (c) 0.27 ppm peroxyacetylnitrate in filtered air, PAN; and (d) a combination of all three mixtures, PANCO. There was no significant change in maximum aerobic power $$\left( {\dot VO2max} \right)$$ related to the presence of air pollutants, although total working time was lowered in the 25°C environment while breathing CO. Older nonsmokers did have a decrement in $$\left( {\dot VO2max} \right)$$ while breathing 50 ppm CO, while older smokers failed to show any change. This difference was related to the initial COHb levels of the smokers, who, when breathing this level of ambient CO, had only a 14% increase in COHb over their initial levels in contrast to the 200% increase in the nonsmokers. Smoking habits were the most influential factor affecting the cardiorespiratory responses of these older men to maximal exercise. Regardless of ambient conditions, smokers had a significantly lower (27%) aerobic power than nonsmokers, were breathing closer to their maximal breathing capacities throughout the walk, and had a higher respiratory exchange ratio. While the $$\left( {\dot VO2max} \right)$$ of nonsmokers was only 6% less than that of younger nonsmoking males ( $$\bar x$$ age = 25 years) working under similar conditions, the aerobic power of the older smokers was 26% lower than that of young smokers ( $$\bar x$$ age = 24 years).Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0191-6599Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: HistoryPolitical ScienceType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The effects of the receptor destroying enzyme (RDE), potassium periodate and trypsin on the non-specific inhibitors and specific antibodies were studied, employing the haemagglutination inhibition and neutralization tests. It was found that whereas RDE and potassium periodate had no deleterious action on specific antibodies even after 64 hours of treatment, trypsin caused a readily demonstrable decrease in the specific antibody titre already during the first 30 minutes of treatment.Type of Medium: Electronic ResourceURL: -
19Hunkapiller, M. ; Kent, S. ; Caruthers, M. ; Dreyer, W. ; Firca, J. ; Giffin, C. ; Horvath, S. ; Hunkapiller, T. ; Tempst, P. ; Hood, L.
[s.l.] : Nature Publishing Group
Published 1984Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A series of automated instruments that use state-of-the-art chemical methods has been developed for high-sensitivity protein sequencing, DNA synthesis and peptide synthesis. These intruments have been integrated into a centralized microchemical facility in order to promote their use for the study ...Type of Medium: Electronic ResourceURL: -
20Variability of physiological parameters of unacclimatized males during a two—hour cold stress of 5°CStaff View
ISSN: 1432-1254Source: Springer Online Journal Archives 1860-2000Topics: GeographyPhysicsDescription / Table of Contents: Zusammenfassung Die Reaktionen des Stoffwechsels und der Hauttemperatur von 11 männlichen Angehörigen der weissen Rasse während einer 2-stündigen Exponierung bei 5 ± 1°C, 50–70 % RF wurden mit den Kontrollwerten bei 28 ± 1°C und 45 ± 2% RF verglichen. Während der Kälteexponierung stieg die Wärmebildung an und erreichte wie die Hauttemperatur in den letzten 30 Min ein ungefähr konstantes Niveau. Die Gruppenvariabilität war in den ersten 30 Min am grössten und liess dann nach. Die Korrelation zwischen mittlerer Hauttemperatur und Oberschenkeltemperatur war hochsignifikant (p 〈 0,001). Es wird vorgeschlagen letztere als mittlere Hauttemperatur zu verwenden. Die Berechnung der Gewebeleitfähigkeit mit oder ohne Einbeziehung des Wärmeaustausches als Folge von Änderungen des Wärmegehaltes des Körpers und Wärmeverlustes bei der Atmung stimmte nur während der letzten 30 Min. Alle gemessenen Parameter ausser der Zehen- und Fingertemperatur näherten sich während der letzten 30 Min der Kälteexponierung einer minimalen Variabilität. Dies weist auf ein physiologisches Gleichgewicht hin.Abstract: Resume On a comparé le métabolisme et la température cutanée de 11 personnes de la race blanche caucasienne exposées durant 2 heures à une température de 5 ± 1°C et à une humidité relative de 70 ± 2% aux mêmes valeurs obtenues par 28 ± 1°C et 45 ± 2%. La production de chaleur a augmenté durant l'exposition au froid pour atteindre un niveau relativement stable durant les 30 dernières minutes. La variabilité du groupe quant à la réaction au froid fut très importante durant les 30 premières minutes. Elle a notablement diminué le reste du temps. Toutes les températures cutanées se sont stabilisées durant les 30 dernières minutes de l'exposition au froid. La corrélation entre la température de la peau et celle de la cuisse fut hautement significative (p 〈 0,001) et l'on propose d'utiliser cette dernière température comme température cutanée moyenne. Le calcul de la conductibilité des tissus en y incluant ou excluant les échanges de chaleur dus aux variations thermiques du corps ou les pertes imputables à la respiration n'est exact que pour les 30 dernières minutes. Tous les paramètres mesurés, à l'exception des températures des doigts et des orteils tendent vers un minimum de variabilité durant ce même laps de temps. Ceci indique qu'un état d'équilibre physiologique est alors atteint.Notes: Abstract The metabolic and temperature responses of 11 male Caucasians to a 2-hr exposure to 5 ± 1°C, 70 ± 2% RH were compared with control data obtained in an ambient environment of 28 ± 1°C, 45 ± 2% RH. The heat production increased during the cold exposure attaining an approximately stable level during the final 30 min. The group variability in response to the cold was greatest during the first 30 min and declined for the remainder of the cold exposure. All skin temperatures approached a stable value during the final 30 min of cold exposure. The correlation between mean skin temperature and thigh temperature was significant (p 〈 0.001) and the use of thigh temperature as an approximate mean skin temperature was suggested. The calculation of tissue conductance with or without the inclusion of heat exchanges due to changes in body heat content and respiratory losses was in agreement only during the final 30 min of cold exposure, thus indicating a stage of physiological equilibrium. All measured parameters except the toe and finger temperatures approached minimum variability of response during the final 30 min of cold exposure.Type of Medium: Electronic ResourceURL: