Search Results - (Author, Cooperation:R. D. Cardiff)

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  1. 1
    Staff View
    Publication Date:
    2015-08-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Breast Neoplasms/*genetics/*pathology ; Cell Dedifferentiation/genetics ; Cell Lineage/*genetics ; Cell Transformation, Neoplastic/genetics ; Female ; Humans ; Mammary Glands, Animal/metabolism/pathology ; Mammary Neoplasms, Animal/*genetics/*pathology ; Mice ; Multipotent Stem Cells/*metabolism/pathology ; Mutation/genetics ; Neoplasm Invasiveness/genetics/pathology ; Phosphatidylinositol 3-Kinases/*genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2011-03-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    National Institutes of Health (U.S.)/*organization & administration ; Translational Medical Research/*organization & administration ; United States
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    ISSN:
    1433-8726
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Since the detection of abnormal DNA content in the cells of transitional cell carcinoma can be obscured by the presence in the population of diploid stromal and inflammatory cells, it would be desirable to have a second flow cytometric parameter to complement DNA analysis. The specific identification of carcinoma cells using monoclonal antibodies directed against epithelial intermediate filament proteins (cytokeratins) would provide a method with which to identify the transitional cells in solid tumors, voided urines or bladder washings. As a preliminary study we have tested cell-free urine samples using a double antibody radiometric assay (IRMAK) for cytokeratins released from transitional cells. The additional information from cytokeratin analyses increased the specificity of disease detection.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00327069

    Articles: DFG German National Licenses
  4. 4
    Cardiff, R. D. ; Dalrymple, J. M. ; Russell, P. K.
    Springer
    Published 1973
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01242561

    Articles: DFG German National Licenses
  5. 5
    Young, L. J. T. ; Cardiff, R. D. ; McGrath, C. M.
    Springer
    Published 1975
    Staff View
    ISSN:
    1573-0603
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00922606

    Articles: DFG German National Licenses
  6. 6
    Cooper, R. A. ; Cardiff, R. D. ; Wellings, S. R.
    Springer
    Published 1967
    Staff View
    ISSN:
    1432-0878
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Summary In 10-day-old Balb/cCrgl mice, the subcutaneous injection of 0.1 μg of estradiol in distilled water per animal per day resulted in the conversion, over a 4 day period, of the original 3 cell layered cuboidal epithelium to a stratified, multilayered, fully keratinized epithelium. By light microscopy, there was development of a prominent stratum germinativum and of a mucinified surface on the 1st day, followed by the sequential formation of a stratum spinosum, a stratum granulosum, and a stratum corneum. By electron microscopy, the principal early modifications consisted of a marked increase in ribosomes, desmosomes, and 70 Å cytoplasmic filaments, the latter being aggregated into approximately 700 Å fibrils. The subsequent establishment of a keratin layer was preceded by the appearance of keratohyaline granules and the disappearance of mitochondria and endoplasmic reticulum in cells immediately above the stratum spinosum and by the development of a transitional cell layer in which there was progressive aggregation of cytoplasmic filaments and disappearance of nuclei, keratohyaline granules, and free ribosomes. In the upper stratum granulosum, transitional cell layer, and stratum corneum there were distinctive modifications in desmosomal structure (composite and modified desmosomes). The morphological and physiological significance of these observations is discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00339242

    Articles: DFG German National Licenses