Search Results - (Author, Cooperation:N. Abdullah)

2018-03-20

Institute of Physics (IOP)

1757-8981

1757-899X

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

2015-09-10

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Alleles ; Alternative Splicing/genetics ; Arecaceae/*genetics/metabolism ; *DNA Methylation ; Epigenesis, Genetic/*genetics ; *Epigenomics ; Fruit/genetics ; Genes, Homeobox/genetics ; Genetic Association Studies ; Genome, Plant/*genetics ; Introns/genetics ; Molecular Sequence Data ; *Phenotype ; Plant Oils/analysis/metabolism ; RNA Splice Sites/genetics ; RNA, Small Interfering/genetics ; Retroelements/*genetics

1365-2133

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

In a dermatoglyphic study of 101 patients with dermatitis herpetiformis, comparison was made with their normal relatives and several random normal series. The results of the several comparisons are quite consistent, considering the nature of the data, for they all point to an attenuation of qualitative and quantitative digital and palmar traits in the patients. It is argued that these differences are associated with the disease itself, and that some of the female relatives have an inherited tendency to the disorder, but do not express it. The findings suggest the involvement of genetic factors in the aetiology, and possibly intrauterine environmental influences as well.

Electronic Resource

1460-2695

Blackwell Publishing Journal Backfiles 1879-2005

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Abstract— Fatigue crack growth in a commercial grade ABS over the temperature range - 50°C to 80°C has been studied. An Arrhenius type relationship between fatigue crack growth rate and absolute temperature was found to describe the experimental data. At ΔK= 1 MPa√m, the activation energy for crack growth in the temperature range −50°C to 19°C is 3.47 kJ/mole and in the temperature range 30°C to 80°C it is 19.63 kJ/mole. The two different activation energies were found to be associated with the roughness of the fracture surfaces. The roughness of the fracture surfaces is discussed in relation to modes of fatigue crack growth. In the low temperature range (− 50°C to 19°C) the fracture surfaces were found to be rather coarse, whereas in the high temperature range (30°C to 80°C) they were found to be somewhat smooth. These different roughnesses were deduced to be due to different modes of crack branching influenced by crazing. A “stress intensity factor”-biased Arrhenius equation for fatigue crack growth successfully predicts growth rates at various temperatures.

Electronic Resource

0377-8401

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

Electronic Resource

0377-8401

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

Electronic Resource

0377-8401

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

Electronic Resource

1574-6968

Blackwell Publishing Journal Backfiles 1879-2005

Biology

Abstract Isolates of anaerobic fungi obtained from the rumen, duodenum and faeces of sheep were identified as Piromyces mae based on their morphological characteristics observed using light microscopy. There was no significant morphological variation among the isolates of P. mae from the rumen, duodenum and faeces. Isozymes of 12 isolates of P. mae (one each from the rumen, duodenum and faeces from 4 different sheep) were analysed by PAGE. A total of 12 isozymes were studied and 5 isozyme loci were successfully typed. They were malic enzyme, malate dehydrogenase, shikimate dehydrogenase, α-esterase and β-esterase. All the isolates of P. mae regardless of whether they were from the rumen, duodenum or faeces or from different animals produced very similar isozyme banding patterns for each of the enzyme systems. The similar isozyme profiles of the isolates indicate that they are of the same species although they exist in different regions of the alimentary tract.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract The effect of porcine C5ades Arg and C3a, given as a bolus injection, in the isolated constant flow pumpperfused guinea-pig kidney was investigated. Only C5ades Arg showed activity which was manifested by a dose-dependent increase in perfusion pressure (PP, due to vasoconstriction) and histamine release. Although histamine release was substantial, it alone could not account for the increase in PP. The two more likely causes are a direct vasoconstrictor effect and the release of other mediators.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract In vitro perfused kidneys of ovalbumin-sensitized guinea-pigs consistently released relatively large quantities of histamine when challenged with the specific antigen (mean±SEM in twelve experiments was 37.7±6.0% of total kidney histamine, maximum 70.6%, compared with a basal release of 0.5±0.46% over a comparable period) but not with non-cross-reacting antigens. There was also no release from non-sensitized kidney. Rabbit antisera to guinea pig IgG1 and IgG2 immunoglobulins (but not normal rabbit serum) also consistently released histamine from perfused kidneys of sensitized guinea-pigs, but the release was smaller than with antigen, and could also be obtained from kidneys of non-sensitized guinea-pigs (maximum release 62.4% with the most potent antiserum). Guinea-pig kidney cell suspensions prepared by collagenase dispersion in vitro responded similarly, but the release with antigen was small (〈10% net release, minus the spontaneous release 9.46% on average) as compared to anti-IgG1 (net release up to 38%) or anti-IgG2 (up to 44%). Rat kidney cells prepared by a similar procedure, and passively sensitized in vitro by incubation with rat immunoglobulin E (IgE) myeloma protein also responded to the addition of antiserum to rat IgE by releasing substantial amounts of histamine (up to 44% net release). In addition, heparin-containing cells (presumably mast cells or equivalent) in the enzyme-dispersed kidney cell preparations in both species were identified and counted by an adaptation of the Technicon H 6000 system used for counting blood basophils, and shown to represent 1 in 10000 or less of the total cell population, which was not different from the count of similar cells in lung and heart tissues. It is likely that at least part of renal histamine content (0.87–1.85 μg/g wet tissue in our experiments) is stored in these cells. These findings show that histamine contained in kidney tissue can be released in anaphylactic reactions in a similar way and magnitude as in lung tissue. They also suggest that histamine can play a role as a mediator of immune and inflammatory reactions affecting the kidney, and that there are mast cells in this organ.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract A comparison was made between collagenase-dispersed guinea-pig atrial and ventricular tissues. Heparin containing cells were stained with alcian blue at pH 2.2, and counted by an automated technique (Technicon H6000). The cells were challenged with the specific antigen (ovalbumin), with antisera to guinea-pig IgG (non-subclass specific), IgG1 and IgG2, and the calcium ionophore A23187. Histamine release was measured by an automated spectrofluorometric technique, and leukotriene C4 was measured by radioimmunoassay. All of the following parameters were higher in the atrial than in ventricular cells (mean ratio and SEM of atrial: ventricular mast cell parameters in parenthesis): 1) Histamine content/g wet tissues (3.32±0.71:1) (p〈0.05), 2) Absolute mast cell number as a proportion of total cell count (3.75±1.64:1), 3) Histamine release induced by antigen (significant in one out of four experiments), anti-IgG (significant in three out of four experiments), anti-IgG1 (significant in two out of four experiments), and anti-IgG2 (higher but not statistically significant). Ionophore A23187 gave an inconsistent histamine release pattern: significantly higher release from atria in five treatments (different concentrations in different experiments), and higher ventricular release in three. Significantly more leukotriene C4 was released by antigen and the ionophore A23187 (mean of 3–5 treatments), but not with anti-IgG.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract We report a pilot study of mast cells and IgE-mediated release of histamine, leukotrienes and thromboxanes from human kidney. The results together with previous findings in the guinea-pig and rat suggest that mast cells and IgE may play an important role in kidney diesease.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract Antigen challenge of isolated perfused kidneys of sensitized guinea-pigs consistently released a large proportion of their histamine content, and caused a reduction in renal perfusate flow rate (RPFR) which could not simply be due to the released histamine, since much larger amounts of exogenous histamine were needed to produce a comparable effect. Reduction in RPFR by histamine was blocked by mepyramine but not by cimetidine, i.e. it is mediated by an H1-receptor mechanism.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract Renal vasoconstriction and ischaemia that followin vitro antigen challenge of isolated perfused kidney of sensitized guinea-pig appears to be a self-perpetuating process, starting with a primary peak of release of vasoconstrictor mediators and followed by secondary peaks (particularly of arachidonic acid metabolites) which are probably initiated by ischaemia/reperfusion damage.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract This report suggests that the release of various inflammatory mediators such as histamine, LTC4, D4 and E4, and TXA2 measured as the stable metabolite TXB2 are partly responsible for the various cardiac and renal effects of the complement fragment C5a des Arg anaphylatoxin, in addition to its direct vasoconstrictor activity.

Electronic Resource

1420-908X

Springer Online Journal Archives 1860-2000

Medicine

Abstract The existence of a role for TXA2, histamine, and possibly LTC4 in the antigen-induced renal vasoconstriction in isolated, perfused kidney of sensitized guinea-pigs is demonstrated.

Electronic Resource

1572-9893

Springer Online Journal Archives 1860-2000

Geography

Abstract The present paper reviews the conservation movement in Saudi Arabia as measured against the established protected areas, as well as the basic philosophy regarding natural resource management. The degree of representation of the biophysical diversity of Saudi Arabia in the established protected areas is discussed by using three areas as case studies: Harrat Al-Harrah (lava field), Urug Bani Mu'arid (Cuesta and Sand), and Raydah Escarpment (High Mountain).

Electronic Resource

2018-06-02

Institute of Physics (IOP)

1757-8981

1757-899X

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

2018-02-10

Institute of Physics (IOP)

1757-8981

1757-899X

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics