Search Results - (Author, Cooperation:M. Whiteway)
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1Latest Papers from Table of Contents or Articles in PressO. Ryan ; R. S. Shapiro ; C. F. Kurat ; D. Mayhew ; A. Baryshnikova ; B. Chin ; Z. Y. Lin ; M. J. Cox ; F. Vizeacoumar ; D. Cheung ; S. Bahr ; K. Tsui ; F. Tebbji ; A. Sellam ; F. Istel ; T. Schwarzmuller ; T. B. Reynolds ; K. Kuchler ; D. K. Gifford ; M. Whiteway ; G. Giaever ; C. Nislow ; M. Costanzo ; A. C. Gingras ; R. D. Mitra ; B. Andrews ; G. R. Fink ; L. E. Cowen ; C. Boone
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-09-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Biofilms/growth & development ; Candida albicans/cytology/*genetics/*growth & development ; DNA Mutational Analysis ; Gene Deletion ; *Gene Expression Regulation, Fungal ; Hyphae/genetics/growth & development ; Nuclear Proteins/genetics ; Saccharomyces cerevisiae/cytology/*genetics/*growth & development ; Saccharomyces cerevisiae Proteins/genetics ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, GeneticPublished by: -
2Latest Papers from Table of Contents or Articles in PressChen, Y., Mallick, J., Maqnas, A., Sun, Y., Choudhury, B. I., Cote, P., Yan, L., Ni, T.-j.-h., Li, Y., Zhang, D., Rodriguez-Ortiz, R., Lv, Q.-z., Jiang, Y.-y., Whiteway, M.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-03-28Publisher: The American Society for Microbiology (ASM)Print ISSN: 0066-4804Electronic ISSN: 1098-6596Topics: BiologyMedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-06Publisher: Wiley-BlackwellPrint ISSN: 0148-0227Topics: GeosciencesPhysicsPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 1046-2023Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Keywords: Acetylcholine receptor ; G protein ; Gene expression ; Radioligand binding ; YeastSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesBussey, H. ; Boone, C. ; Zhu, H. ; Vernet, T. ; Whiteway, M. ; Thomas, D. Y.
Springer
Published 1990Staff ViewISSN: 1420-9071Keywords: Saccharomyces cerevisiae ; protein toxin ; yeast toxin precursor ; protease processing ; lectin ; (1→6)-β-D-glucan ; receptor ; resistant mutants ; spheroplasts ; ion-permeable channels ; site-directed mutagenesis ; toxin functional domainsSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary The K1 killer toxin ofSaccharomyces cerevisiae is a secreted, virally-coded protein lethal to sensitive yeasts. Killer yeasts are immune to the toxin they produce. This killer system has been extensively examined from genetic and molecular perspectives. Here we review the biology of killer yeasts, and examine the synthesis and action of the protein toxin and the immunity component. We summarise the structure of the toxin precursor gene and its protein products, outline the proteolytic processing of the toxin subunits from the precursor, and their passage through the yeast secretory pathway. We then discuss the mode of action of the toxin, its lectin-like interaction with a cell wall glucan, and its probable role in forming channels in the yeast plasma membrane. In addition we describe models of how a toxin precursor species functions as the immunity component, probably by interfering with channel formation. We conclude with a review of the functional domains of the toxin structural gene as determined by site-directed mutagenesis. This work has identified regions associated with glucan binding, toxin activity, and immunity.Type of Medium: Electronic ResourceURL: