Search Results - (Author, Cooperation:M. Saitoh)
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1D. W. Lamming ; L. Ye ; P. Katajisto ; M. D. Goncalves ; M. Saitoh ; D. M. Stevens ; J. G. Davis ; A. B. Salmon ; A. Richardson ; R. S. Ahima ; D. A. Guertin ; D. M. Sabatini ; J. A. Baur
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adipose Tissue, White/metabolism ; Animals ; Carrier Proteins/genetics/metabolism ; Female ; Gluconeogenesis ; Glucose/metabolism ; Glucose Clamp Technique ; Homeostasis ; Insulin/administration & dosage/blood ; *Insulin Resistance ; Liver/metabolism ; *Longevity ; Male ; Mice ; Mice, Inbred C57BL ; Multiprotein Complexes ; Muscle, Skeletal/metabolism ; Phosphorylation ; Proteins/antagonists & inhibitors/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Sirolimus/*pharmacology ; TOR Serine-Threonine Kinases/genetics/metabolismPublished by: -
2Staff View
Publication Date: 2018-02-09Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Emergency medicinePublished by: -
3R. Iguchi, A. Yagmur, Y.-C. Lau, S. Daimon, E. Saitoh, M. Hayashi, and K. Uchida
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-07-03Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: MagnetismPublished by: -
4Kuyama, M. ; Fujimoto, W. ; Kambara, H. ; Egusa, M. ; Saitoh, M. ; Yamasaki, O. ; Maehara, K. ; Ohara, A. ; Arata, J. ; Iwatsuki, K.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary We report two patients with severe amicrobial pustular dermatosis with immunological abnormalities: a 63-year-old woman with a 30-year-history of discoid lupus erythematosus and sicca syndrome, and a 35-year-old woman with high levels of γ-globulinemia and positive antinuclear antibodies. Both patients presented with crusty and eroded erythematous plaques studded with aseptic pustuleson the back, face, and scalp. Histological examination showed acanthosis, neutrophilic exocytosis to the epidermis, and neutrophilic and lymphocytic infiltration with nuclear dust in the dermis. These patients were diagnosed as having ‘amicrobial pustulosis associated with autoimmune diseases’. The eruptions improved with combination treatment of oral prednisolone with cyclosporin A or diaminodiphenylsulphone. Although the pathogenesis remains unclear, amicrobial pustular dermatosis might be one of the cutaneous complications in autoimmune diseases.Type of Medium: Electronic ResourceURL: -
5Morisako, A. ; Saitoh, M. ; Matsumoto, M.
[S.l.] : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Hexagonal strontium-ferrite (SrM) thin films were deposited by sputtering with the target composition ratio N (Fe/Sr) in the range of 8–14. The discrepancy of the composition ratio between the films and the target was found and the deposited films were in Fe-rich. In the x-ray diffraction diagram, the observed diffraction lines varied with the composition of the target and preferential c-axis orientation can be observed in the film prepared with the target, where the composition N is 10. The grain shape as well as size was found to be independent of N. The magnetic easy axis was normal to the plane. The maximum saturation magnetization and coercivity in the perpendicular direction were about 300 emu/cc and 3.5 kOe, respectively, when the film was prepared with the target with N of 8. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Ohura, M. ; Tsuji, Y. ; Kuwatsuka, S. ; Hanazono, M. ; Kawakami, K. ; Saitoh, M.
[S.l.] : American Institute of Physics (AIP)
Published 1987Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Thin-film heads for 8.8-in.-diam particulate media rigid disks having a recording density of 20 kBPI were designed utilizing numerical analysis techniques and experimental results. The heads having a total thickness of 3.5 μm (outer edge to edge length in media movement direction) and gap depth of less than 1.5 μm provide satisfactory reproducing and recording characteristics. A novel head structure was developed for which the magnetic path is closed at the front end of the gap film to simplify detection of the end point in the polishing process in order to achieve the desired gap depth. The head is fabricated by adding two steps to the conventional process before the top magnetic film is deposited. These steps are (1) removing a part of the gap film, masking by the top organic insulating film, by using carbon tetrafluoride ion and (2) etching back the organic film so as to expose the gap film from the edge of the organic film that determine the cardinal point of the head gap.Type of Medium: Electronic ResourceURL: -
7Kamada, Y. ; Utsumi, M. ; Saitoh, M. ; Morikawa, J. ; Nihei, H. ; Yoshida, Z. ; Inoue, N.
[S.l.] : American Institute of Physics (AIP)
Published 1987Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: A hydrogen beam probing system developed for the REPUTE-1 reversed field pinch device is described. With this system, the plasma ion line density, the central ion temperature, and the magnetic field profile can be measured. Before being applied to the REPUTE-1 device, the probing system was tested on the TORIUT-5 tokamak and TORIUT-6 ultralow-q (ULQ) devices. The experimental results show the availability of the system. The measured line density agrees well with that measured by the microwave interferometry. The measurable density ranges from 1019 m−3 to 3×1020 m−3. A new method of magnetic field measurement which is effective and important for RFP plasmas is proposed. The resolution and the accuracy of this measurement have been confirmed by experiments on the TORIUT-5 device. Experimental results agree well with computation.Type of Medium: Electronic ResourceURL: -
8Yamada, M. ; Nada, N. ; Saitoh, M. ; Watanabe, K.
Woodbury, NY : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A novel method of fabricating a periodic domain structure with ideal laminar domains in LiNbO3 by applying an external field at room temperature is proposed. The method allows a high blue beam power of 20.7 mW and a high conversion efficiency of 600%/W cm2 to be obtained.Type of Medium: Electronic ResourceURL: -
9Hidaka, T. ; Maruyama, T. ; Saitoh, M. ; Mikoshiba, N. ; Shimizu, M. ; Shiosaki, T. ; Wills, L. A. ; Hiskes, R. ; Dicarolis, S. A. ; Amano, Jun
Woodbury, NY : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Nanometer size polarized domains were written in a PbZr1−xTixO3 (PZT) thin film using an atomic force microscope (AFM) and the relationship between the polarized domain and the grain of the film was investigated. The polarized domain was formed by applying a pulse voltage to the ferroelectric PZT thin film through a conductive AFM tip. The polarized domain structure was observed by imaging the piezoelectric-induced surface vibration by an AFM with an ac voltage applied between the tip and the bottom electrode of a sample. The polarized domains with a diameter of 50 nm were written within a single grain. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
10Maruyama, T. ; Saitoh, M. ; Sakai, I. ; Hidaka, T.
Woodbury, NY : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A 10-nm-thick PbZr0.25Ti0.75O3 thin film is epitaxially grown on a SrRuO3/BaTiO3/ZrO2/Si heterostructure substrate by reactive evaporation. Structural and electrical properties of the film are investigated. It is concluded that the film is ferroelectric and retains a native uniform upward polarization. Artificial downward polarization domains, whose average diameter is 24 nm, can be formed in the film. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11Yamada, M. ; Saitoh, M. ; Ooki, H.
Woodbury, NY : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Three kinds of electro-optic devices composed of the inverted domains in LiNbO3 substrates were fabricated. The devices are induced and controlled by applying an electric field. The three devices are: (i) a cylindrical lens with an aperture of 340 μm and length of 10 mm, which can tune the focusing length from 20 to 50 mm depending on an electric field ranging from 250 to 150 V/mm, (ii) an optical switching device composed of a periodically inverted domain structure, which can reflect the whole power of an incident light beam by applying an electric field of 700 V/mm, and (iii) a deflection device with a deflection angle of about 5°, depending on an electric field of 750 V/mm. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0167-4781Keywords: (Mammalian cell and tissue) ; (Rat brain) ; Cβ catalytic subunit ; Expression ; cAMP-dependent protein kinase ; cDNASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1460-2695Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: This study concerns MCrAlY coatings (M is Ni, Co or both) sprayed by a vacuum plasma spraying process for protection against high-temperature corrosion and oxidation of gas turbine components, such as turbine blades and duct segments. The effect of high-temperature protective coatings on fatigue lives of nickel-based superalloys were investigated at high temperature under push–pull loading and rotary bending and then compared with uncoated superalloys, such as equiaxed IN738LC, unidirectional solidified CM247LC and single-crystal CMSX-2. The high-cycle fatigue lives of MCrAlY-coated superalloys at high temperature under push–pull loading showed an inferior performance when compared with the uncoated superalloys. This was because the crack initiation site was different. The high-cycle fatigue cracks of nickel-based superalloys initiated at casting cavities which were exposed on the specimen surface, whereas the high-cycle fatigue cracks of MCrAlY-coated specimens initiated at interface defects, such as small pores and grid residue, between the MCrAlY coating and the substrate and grew into the MCrAlY coating, and then into the substrate. Similarly, the rotary bending fatigue properties of MCrAlY-coated superalloys at high temperature showed an inferior performance when compared with the uncoated superalloys. This is because of a high stress due to the higher Young’s modulus of the MCrAlY coating (in comparison with the substrate) being induced at the MCrAlY coating surface. The crack initiation site was on the specimen surface in both cases of the nickel-based superalloys and the MCrAlY-coated superalloys, respectively. As a result, it was considered that, for rotary bending tests, the fatigue life reduction was due to the high stress that originated from the difference of elastic constants between the MCrAlY coating and the superalloy. Consequently, in fatigue life design it is necessary to take account of the stress levels in a coating layer.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0304-8853Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0005-2736Keywords: 1,25-Dihydroxyvitamin D-3 ; ATPase, Ca^2^+- ; Basolateral membrane ; Calcium pump ; Parathyroid hormoneSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
18Niki, I. ; Okazaki, K. ; Saitoh, M. ; Niki, A. ; Niki, H. ; Tamagawa, T. ; Iguchi, A. ; Hidaka, H.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0377-8401Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: