Search Results - (Author, Cooperation:M. Michaud)

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  1. 1
    Staff View
    Publication Date:
    2012-09-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Calreticulin/immunology ; Cell Line, Tumor ; Common Variable Immunodeficiency/genetics ; DNA, Neoplasm/analysis/genetics ; Endoplasmic Reticulum Stress/*immunology ; Eukaryotic Initiation Factor-2/metabolism ; Humans ; Immunocompetence ; *Immunologic Surveillance ; Mice ; Mice, Inbred BALB C ; Neoplasms/chemically induced/*genetics/*immunology ; Phosphorylation ; *Ploidies
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    M. R. Howitt ; S. Lavoie ; M. Michaud ; A. M. Blum ; S. V. Tran ; J. V. Weinstock ; C. A. Gallini ; K. Redding ; R. F. Margolskee ; L. C. Osborne ; D. Artis ; W. S. Garrett
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-02-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Chemoreceptor Cells/*immunology ; Eosinophils/immunology ; Goblet Cells/immunology ; Helminthiasis/immunology/parasitology ; Helminths/immunology ; Immunity, Mucosal ; Interleukin-13/immunology ; Interleukin-17/immunology ; Intestinal Diseases, Parasitic/*immunology/parasitology ; Intestinal Mucosa/*immunology/*parasitology ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Microbiota/*immunology ; Protein-Serine-Threonine Kinases/immunology ; Protozoan Infections/immunology/parasitology ; Signal Transduction ; TRPM Cation Channels/*immunology ; Taste ; Transducin/genetics/immunology ; Tritrichomonas/immunology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    P. M. Smith ; M. R. Howitt ; N. Panikov ; M. Michaud ; C. A. Gallini ; Y. M. Bohlooly ; J. N. Glickman ; W. S. Garrett
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-07-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacteria/*metabolism ; Colitis/metabolism ; Colon/*microbiology ; DNA-Binding Proteins/genetics ; Fatty Acids, Volatile/administration & dosage/*metabolism ; Fermentation ; Germ-Free Life ; *Homeostasis ; Humans ; *Metagenome ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Receptors, G-Protein-Coupled/genetics/metabolism ; T-Lymphocytes, Regulatory/*physiology/transplantation
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2011-12-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine Triphosphate/metabolism ; Animals ; Antineoplastic Agents/*pharmacology/therapeutic use ; Autophagy/drug effects/*physiology ; Calreticulin/pharmacology ; Cell Death/immunology ; Cell Line, Tumor ; Dendritic Cells/immunology ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mitoxantrone/pharmacology ; Neoplasms/drug therapy/*immunology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Michaud, M. ; Cloutier, P. ; Sanche, L.

    [S.l.] : American Institute of Physics (AIP)
    Published 1995
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    We report on the design and performance of a low-temperature sample manipulator for ultrahigh-vacuum surface studies. The arrangement consists essentially of modified commercial sample manipulator coupled to a closed-cycle helium refrigerator. The device allows a metal sample or a substrate, which is electrically isolated, to be cooled down to 16 K and heated up to 1100 K for cleaning and annealing purposes. Besides, the sample can be translated by ±0.5 cm in three perpendicular directions (X, Y, and Z axes), rotated by ±100° azimuthally along the main shaft (Z axis), and flipped over a range of 50° about an axis perpendicular to the main shaft. The sample holder, which includes the rotation supports, is sufficiently compact to be manipulated without hindrance as close as 1.4 cm from a given instrumentation. A simple mathematical model is developed to predict the cooling capacity of the present design or that of similarly constructed devices. © 1995 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1145606

    Articles: DFG German National Licenses
  6. 6
    Swiderek, P. ; Fraser, M.-J. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Low-energy electron-energy-loss spectra of styrene deposited on a thin film of solid argon are measured at a temperature of 15 K. The spectra show vibrationally resolved bands in the region of the lowest valence transitions thus allowing to locate the 0–0 transition to the lowest triplet state at 2.69 eV. The second triplet state of styrene is detected for the first time with a 0–0 transition at 3.98 eV. Semiempirical calculations are performed to characterize the bands observed in the spectrum considering the nomenclature of Platt. They suggest that the lowest triplet state has the same spacial wave function as the second singlet state and is closely related to 3La benzene. The second triplet state which has most likely Ba character cannot directly be related to a specific singlet state because the Ba and Bb states are found to mix strongly in the singlet manifold whereas among the triplets they do not.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.466936

    Articles: DFG German National Licenses
  7. 7
    Swiderek, P. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1995
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Low-energy electron-energy-loss spectra of 6,6′-dimethylfulvene deposited on a thin film of solid argon are measured at a temperature of 16 K. The spectra make it possible to locate the lowest triplet state with an onset of the transition band at 1.9 eV and a vertical transition energy of approximately 2.3 eV. This is the first observation of a triplet state in a compound with a pentafulvene π-electron system. Semiempirical calculations, as well as ab initio multiconfiguration self-consistent-field calculations for fulvene using the 4-31G basis set, lead to an assignment of the observed triplet state as 1 3B2. Both 1 3B2 and the lowest excited singlet state 1 1B2 mainly arise from the excitation from the highest occupied molecular orbital to the lowest unoccupied molecular orbital. A singlet-triplet splitting of 1.05 eV is derived for these states. This is about 2.5 times smaller than the corresponding value in an open-chain conjugated 6π-system represented by 1,3,5-trans-hexatriene. The difference expresses the smaller exchange interaction between the highest occupied and lowest unoccupied molecular orbital in fulvene and related compounds. Properties of the lowest triplet state of the parent compound fulvene are calculated by use of the multiconfiguration self-consistent-field method. According to these results the fulvene π-electron system is expected to be planar in this electronic state. The stabilization with respect to a structure twisted by 90° around the exocyclic carbon–carbon bond amounts to 0.62 eV. © 1995 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.470153

    Articles: DFG German National Licenses
  8. 8
    Lepage, M. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    We report on the low-energy electron induced production of CO within thin solid films of acetone condensed at low temperature on a solid Ar substrate. The CO fragments, which remain trapped within the bulk of the acetone film, are detected in situ via their first electronic state a 3Π using high-resolution electron-energy-loss spectroscopy. The production of CO is studied as a function of the electron energy (2–25 eV), electron dose, and film thickness. The energy dependence of CO production is calibrated in terms of an electron scattering cross section σp. It is characterized by an energy threshold at 8 eV, a strong rise up to about 14 eV, and a broad maximum of σp(approximate)6.8×10−17 cm2 at 16 eV followed by a relatively small and monotonous decrease up to 25 eV. The production of CO is discussed in terms of the formation of several core-excited electron resonances, which may lead directly to the fragmentation of the molecule via dissociative electron attachment or indirectly by decaying into an entirely repulsive part of the corresponding neutral excited state and positive ion states. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1287400

    Articles: DFG German National Licenses
  9. 9
    Swiderek, P. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Low-energy electron-energy-loss spectra of solid benzene and toluene in the range of the three low-lying triplet states were recorded at a temperature of 15 K. Vibronic structure within the low-lying triplet bands of toluene is observed for the first time. In the case of benzene the high resolution spectra reveal more details in the vibronic structure than known from previous electron- energy-loss spectra. With this information a modified interpretation of the vibronic structure in the first triplet band of benzene is proposed. The difference between the spectra of toluene and benzene is explained by the influence of vibronic coupling on the lowest triplet state. In addition, the systematic broadening of the vibronic levels within the first and second triplet band of toluene is interpreted as an effect of the side group internal rotation. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.471852

    Articles: DFG German National Licenses
  10. 10
    Swiderek, P. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Low-energy electron-energy-loss spectra of 1,3-butadiene and 1,3-cyclopentadiene deposited on a thin film of solid argon are measured at a temperature of 15 K. This new method allows us to resolve vibrational structure within the low-lying triplet bands. The vibrational frequencies observed in the first triplet band of butadiene are in agreement with theoretical predictions under the assumption of a metastable planar structure for the lowest triplet state (1 3Bu). The lowest observable vibronic band of the second triplet transition of butadiene is located at 4.63 eV. The 0–0 transition to the first triplet state of cyclopentadiene is resolved and located at 2.555 eV. Concerning the second triplet band of cyclopentadiene, we find evidence from a comparison with optical spectra that the onset lies in the energy range from 4.55 to 4.7 eV. This is the first likely observation of T2 for a cis-diene.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.464498

    Articles: DFG German National Licenses
  11. 11
    Lepage, M. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1997
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    We propose a method based on high-resolution electron-energy-loss spectroscopy to measure in situ the neutral fragmentation products arising from the impact of low energy electrons on thin solid films at low temperature. We show more particularly that the detection of electronic states from a dissociation product is a good alternative when the corresponding vibrational levels are obscured by those of the deposited film. In the case of thin methanol film condensed at 18 K, we find that low energy electrons can dissociate the CH3OH molecules into CO fragments that remain within the film. The production of CO fragments, clearly identified from its lowest electronic state a 3Π, is studied as a function of the electron dose, electron energy, and film thickness. The energy dependence of the CO production rate, which is also calibrated in terms of an electron total scattering cross section σp, is characterized by an energy threshold at 8 eV, a shoulder at about 11.5 eV, a broad maximum centered around 14 eV, and a rise above 19 eV. A value of σp(approximate)4.2×10−18 cm2 is obtained at 14 eV. The shoulder and the broad maximum are specifically attributed to the (centered ellipsis)(6a′)1(3sa′)2,2A′, (centered ellipsis)(1a″)1(3sa′)2,2A″, and (centered ellipsis)(5a′)1(3sa′)2,2A′ core excited electron resonances, which decay into their parent repulsive states. The rise above 19 eV is correlated to the lowest dissociative photoionization processes known to produce neutral CO in the gas phase. © 1997 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.474485

    Articles: DFG German National Licenses
  12. 12
    Lepage, M. ; Michaud, M. ; Sanche, L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    We report electron-energy-loss spectroscopy, within the incident electron energy range 1 to 19 eV, of solid films of acetone condensed at 18 K. The strong Rydberg progressions, which usually dominate the spectra in the gas phase, are found to completely disappear in the solid phase. In the absence of these transitions, the remaining broad bands centered at 4.3, 4.5, 6.2, 8.7, and 9.8 eV energy loss can be assigned to the 1 3A2(n→π*), 1 1A2(n→π*), 1 3A1(π→π*), 1 3B1(σ→π*), and 2 3A2(σ→π*) valence electronic transition of acetone, respectively. A broad feature ranging from 11 to 16 eV and having a maximum around 13.8 eV is ascribed to several overlapping autoionizing excited states. From a comparison with infrared and Raman spectra, the energy-loss peaks observed below 1 eV are found to be due to excitation of the fundamental, overtone, and combination vibrational modes of the molecule. Their incident energy dependence is showing broad vibrational enhancement maxima at 4, 7, and 9 eV, which are attributed to the formation of single-particle or shape resonances of 2B1, 2A1, and 2A2 (or 2B2) symmetries, respectively. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.481245

    Articles: DFG German National Licenses
  13. 13
    Sanche, L. ; Perluzzo, G. ; Michaud, M.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1985
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Pseudovibrational levels of the 2Πg state of N−2 are detected via electron transmission through solid xenon films doped with varying concentrations of nitrogen molecules. The resonance is found to produce a significant increase in transmitted current arising from electrons having lost energy to vibrational excitation. The relaxation shifts of the anion in condensed N2 (0.7 eV), argon (0.83 eV), and xenon (1.45 eV) are discussed and compared with calculations made within the framework of the Mott–Littleton and Born models.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.449094

    Articles: DFG German National Licenses
  14. 14
    Michaud, M. ; Dutil, J.-D. ; Dodson, J. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1988
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    The time elvers of the American eel, Anguilla rostrata, spend in an estuary prior to their migration into fresh water was assessed. A distinct mark was formed on elvers' otoliths during their first 2 to 3 weeks in the river estuary. This mark was used to distinguish between growth in fresh water and in salt water. Migrating eels collected at a falls 4 km from the estuary exhibited bimodal length and weight distributions. Frequency distributions showed that eels collected in the estuary were smaller and had smaller otoliths than eels collected at the falls, indicating that elvers do not reach the falls in the same year as they enter the estuary. The three modal groups most probably represent three age–classes. However, the otoliths of elvers collected in the estuary had only the mark of transition whereas eels in the first and second mode at the falls usually had two rings (1–4) and four rings (3–6) per otolith, respectively, in addition to the mark of transition, as viewed under SEM. The possibility that ring formation is not annual means that the use of otoliths for the age determination of eels in this study has not been validated.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.1988.tb05351.x

    Articles: DFG German National Licenses
  15. 15
    Sanchez, C. ; Michaud, M. ; Livage, J. ; Herve, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-1902
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0022-1902(81)80619-7

    Articles: DFG German National Licenses
  16. 16
    Michaud, M. ; Sanche, L. ; Gaubert, C. ; Baudoing, R.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0039-6028
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0039-6028(88)90297-X

    Articles: DFG German National Licenses
  17. 17
    Swiderek, P. ; Michaud, M. ; Hohlneicher, G. ; Sanche, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-2614
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-2614(91)87071-I

    Articles: DFG German National Licenses
  18. 18
    Swiderek, P. ; Michaud, M. ; Hohlneicher, G. ; Sanche, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-2614
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-2614(91)90440-K

    Articles: DFG German National Licenses
  19. 19
    Swiderek, P. ; Michaud, M. ; Hohlneicher, G. ; Sanche, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-2614
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-2614(90)85600-H

    Articles: DFG German National Licenses
  20. 20
    Sanche, L. ; Michaud, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-2614
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-2614(81)80393-4

    Articles: DFG German National Licenses