Search Results - (Author, Cooperation:M. A. King)
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1Latest Papers from Table of Contents or Articles in PressL. A. Stevens ; M. D. Behn ; J. J. McGuire ; S. B. Das ; I. Joughin ; T. Herring ; D. E. Shean ; M. A. King
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressM. A. King ; R. J. Bingham ; P. Moore ; P. L. Whitehouse ; M. J. Bentley ; G. A. Milne
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-10-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Antarctic Regions ; Artifacts ; Freezing ; *Gravitation ; *Ice Cover ; *Models, Theoretical ; Oceans and Seas ; Research Design ; *Satellite Communications ; Seawater/*analysis ; Time Factors ; UncertaintyPublished by: -
3Latest Papers from Table of Contents or Articles in PressL. A. Stevens ; M. D. Behn ; J. J. McGuire ; S. B. Das ; I. Joughin ; T. Herring ; D. E. Shean ; M. A. King
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-07-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Latest Papers from Table of Contents or Articles in PressA. Shepherd ; E. R. Ivins ; G. A ; V. R. Barletta ; M. J. Bentley ; S. Bettadpur ; K. H. Briggs ; D. H. Bromwich ; R. Forsberg ; N. Galin ; M. Horwath ; S. Jacobs ; I. Joughin ; M. A. King ; J. T. Lenaerts ; J. Li ; S. R. Ligtenberg ; A. Luckman ; S. B. Luthcke ; M. McMillan ; R. Meister ; G. Milne ; J. Mouginot ; A. Muir ; J. P. Nicolas ; J. Paden ; A. J. Payne ; H. Pritchard ; E. Rignot ; H. Rott ; L. S. Sorensen ; T. A. Scambos ; B. Scheuchl ; E. J. Schrama ; B. Smith ; A. V. Sundal ; J. H. van Angelen ; W. J. van de Berg ; M. R. van den Broeke ; D. G. Vaughan ; I. Velicogna ; J. Wahr ; P. L. Whitehouse ; D. J. Wingham ; D. Yi ; D. Young ; H. J. Zwally
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-12-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antarctic Regions ; *Climate Change ; Geographic Information Systems ; Greenland ; *Ice CoverPublished by: -
5Latest Papers from Table of Contents or Articles in PressA. M. King ; S. A. Reid-Yu ; W. Wang ; D. T. King ; G. De Pascale ; N. C. Strynadka ; T. R. Walsh ; B. K. Coombes ; G. D. Wright
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-06-27Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anti-Bacterial Agents/pharmacology ; Aspartic Acid/*analogs & derivatives/isolation & purification/pharmacology ; Aspergillus/chemistry ; Biological Products/isolation & purification/pharmacology ; Carbapenems/*pharmacology ; Drug Evaluation, Preclinical ; Drug Synergism ; Female ; Gram-Negative Bacteria/*drug effects/enzymology/genetics ; Klebsiella pneumoniae/drug effects/enzymology/genetics ; Mice ; Thienamycins/*pharmacology ; beta-Lactam Resistance/*drug effects ; *beta-Lactamase Inhibitors ; beta-Lactamases/genetics/metabolismPublished by: -
6Articles: DFG German National LicensesKing, M. A. ; Maier, J. P. ; Ochsner, M.
College Park, Md. : American Institute of Physics (AIP)
Published 1985Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The A˜ 2Π←X˜ 2Π laser-excitation spectra of chloroacetylene and deuterochloroacetylene cations are reported. Analysis of the band systems yields values for all three stretching fundamentals (ν1–ν3) in the excited elecronic state. Rotationally resolved spectra of the 000Ω =3/2 subbands have been recorded and analyzed. The derived rotational constants allow estimates of the H–Cl distances in both electronic states to be made.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1435-1463Keywords: GABA ; inhibition ; enhancement ; fatty acid ; depressionSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary GHB produced a concentration-dependent depression of evoked synaptic field potentials (EFPs) recorded extracellularly in the CA1 region of the in vitro rat hippocampal slice. The concentration/response function revealed a threshold near ImM, with IC50 of 10.85 mM and a Hill coefficient of 1.29. The gamma-aminobutyric acid B-receptor (GABA-B) agonist baclofen also depressed the EFP, but even maximally effective concentrations of the GABA-B antagonist 2-hydroxy-saclofen (800 μM) could not completely block the GHB-induced EFP depression. Nor was GHB-induced EFP depression blocked by the GHB receptor “antagonist” NCS-382, which does not displace GABA-B receptor ligands. However, NCS-382 produced a concentration-dependent increase in EFP slope. The threshold concentration was about 100 μM but the maximally effective concentration, and thus the IC50, could not be determined in the perfusion slice system. NCS-382 may be an inverse agonist at hippocampal GHB receptors, or else endogenous hippocampal GHB receptor ligands mediate a tonic inhibition in CA1. At concentrations sufficient to induce EFP depression GHB did not alter pH. Although isosmotic sucrose did depress CA1 EFPs it was essentially ineffective at the IC50 for GHB. Gamma-butyrolactone, a prodrug of GHB, was only 1/20th as effective as GHB. This is consistent with previous data suggesting that GBL is freely permeable (does not substantially disturb tonicity) and that brain has very little capacity to either enzymatically convert the lactone to GHB or respond to the lactone itself.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesBianco, J. A. ; Elmaleh, D. R. ; Leppo, J. A. ; King, M. A. ; Moring, A. ; Livni, E. ; Espinoza, E. ; Alpert, J. S. ; Strauss, H. W.
Springer
Published 1986Staff ViewISSN: 1619-7089Keywords: Glucose and insulin infusion ; Myocardialextraction ; Radioiodinated methyl-substituted fatty acidSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We investigated the one-way. AV extraction of 14-iodophenyl-tetradecanoic acid (BMTDA) in the canine heart under fasting conditions and during infusion of glucose plus insulin in eight anesthetized greyhound dogs. Myocardial extraction measurements were made with dual tracer approach, using Tc-99m albumin as reference tracer. Prior to, and during, infusion of 10% glucose and 25 units of regular insulin, heart rate, blood pressure, plasma glucose, insulin and free fatty acid levels were measured. Myocardial blood flow was determined using Sn-113 and Ru-103 radioactive microspheres. The mean extraction fraction of BMTDA was 0.38±SEM 0.06 at baseline and increased to 0.44±0.06 during hyperglycemia plus insulin (P〈0.025). Plasma glucose and insulin were higher during the infusion (P〈0.01) while plasma free fatty acids significantly declined (P〈0.01). There were no changes in hemodynamics or myocardial blood flow during the infusion. We conclude that glucose and insulin infusion result in increased firstpass extraction fraction of radioiodinated BMTDA unaccompanied by changes in coronary flow or hemodynamics, implying an insulin-mediated augmented transport of BMTDA.Type of Medium: Electronic ResourceURL: