Search Results - (Author, Cooperation:L. Little)
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1Latest Papers from Table of Contents or Articles in PressJ. Zhang ; J. Fujimoto ; D. C. Wedge ; X. Song ; S. Seth ; C. W. Chow ; Y. Cao ; C. Gumbs ; K. A. Gold ; N. Kalhor ; L. Little ; H. Mahadeshwar ; C. Moran ; A. Protopopov ; H. Sun ; J. Tang ; X. Wu ; Y. Ye ; W. N. William ; J. J. Lee ; J. V. Heymach ; W. K. Hong ; S. Swisher ; Wistuba, II ; P. A. Futreal
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-10-11Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenocarcinoma/*genetics/pathology ; DNA Mutational Analysis ; Exome/genetics ; Genes, Neoplasm ; *Genetic Heterogeneity ; Humans ; Lung Neoplasms/*genetics/pathology ; Mutation ; Neoplasm Recurrence, Local/*genetics/pathologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressJohnston, L., Power, M., Sloan, P., Long, A., Silmon, A., Chaffey, B., Lisgo, A. J., Little, L., Vercauteren, E., Steiniche, T., Meyer, T., Simpson, J.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-03-21Publisher: BMJ Publishing GroupPrint ISSN: 0021-9746Electronic ISSN: 1472-4146Topics: MedicineKeywords: Open accessPublished by: -
3Latest Papers from Table of Contents or Articles in PressTakahashi, K., Hu, B., Wang, F., Yan, Y., Kim, E., Vitale, C., Patel, K. P., Strati, P., Gumbs, C., Little, L., Tippen, S., Song, X., Zhang, J., Jain, N., Thompson, P., Garcia-Manero, G., Kantarjian, H., Estrov, Z., Do, K.-A., Keating, M., Burger, J. A., Wierda, W. G., Futreal, P. A., Ferrajoli, A.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-04-20Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid Neoplasia, Clinical Trials and ObservationsPublished by: -
4Articles: DFG German National LicensesFernando, H. J. S. ; Little, L. J.
New York, NY : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsNotes: An experimental study was performed to investigate the influence of molecular diffusion on turbulent entrainment during penetrative convection. The entrainment coefficient E was determined as a function of the Richardson number Ri and Peclet number Pe. It appears that, in parameter ranges 65〈Ri〈150 and 103〈Pe〈104, E is a function of Ri, independent of Pe, which indicates inertial-buoyancy dominated mixing and the unimportance of molecular diffusive effects. At high interfacial stabilities, 30〈Ri〈300, the entrainment law was found to be given by E∼Ri−1.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesNeitzel, G. P. ; Kirkconnell, C. S. ; Little, L. J.
[S.l.] : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsNotes: Laboratory and numerical experiments were conducted to quantitatively determine the modal structure of transient, nonaxisymmetric modes observed during the instability of an impulsively initiated circular-Couette flow. The instability develops initially as an axisymmetric, Görtler-vortex state and persists ultimately as a steady, axisymmetric Taylor-vortex state of different wavelength. The transition between these two states results from the instability of the Görtler mode combined with the underlying developing swirl flow and is dominated by nonaxisymmetric modes. The laboratory experiments employed flow visualization coupled with digital video and image-processing techniques; numerical experiments were performed using the spectral-element code, nekton. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0005-7894Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0005-7894Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0001-9593Topics: Linguistics and Literary StudiesHistoryNotes: RecensioniURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A patient with the naevoid basal-cell carcinoma syndrome (NBCCS) is reported in whom non-aggressive neoplasms developed predominantly on the right side of the body. It is proposed that a post-zygotic somatic mutation is most likely to be responsible for the unilateral manifestation of the syndrome in this patient.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0023-9690Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: EducationPsychologyType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesKnebl, J. ; DeFazio, P. ; Clearfield, M.B. ; Little, L. ; McConathy, W.J. ; Mc Pherson, R. ; Lacko, A.G.
Amsterdam : ElsevierStaff ViewISSN: 0047-6374Keywords: Alzheimer's disease ; Cholesterol esterification ; Down's syndrome ; LCAT ; LipoproteinsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Since that time, Parry4 and Basila, Kantner and Rhee5 have investigated the chemisorption of pyridine and have established conclusively the existence of both Lewis and Bronsted sites on silica-alumina. However, as the results for the chemisorption of ammonia have been widely quoted we have repeated ...Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1572-946XKeywords: Molecular clouds ; HH24–26 ; abundances ; structureSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract New J=1-0 HCO+ and J=2-1 C18O observations of HH24–26 reveal striking differences between these and previous maps of higher-J transitions of HCO+ and CS. The high-J HCO+ and CS emission traces the densest portions of the cloud, while C18O traces the more tenuous envelope. This is also evident in the velocity structure. HCO+ and C18O appear to be depleted from the gas phase by amounts which vary with position.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1435-1536Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1572-9559Keywords: SIS-mixer ; quasiparticle mixer ; millimetre wavesSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The comparison of a 240 GHz SIS heterodyne receiver with a Schottky diode receiver at the Maxwell telescope revealed difficulties with its calibration using continuum loads. The difficulties arise from the fact that the local oscillator power is not hugely greater than the total load power incident across the RF and IR band. This broadband power influences the receiver gain, principally by varying the slope of the I–V characteristic, and hence the output matching, as a result of the ac Josephson effect. Suppressing the Josephson effect with a magnetic field permits the standard calibration procedure, using hot/cold continuum loads, to be employed.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1572-9559Keywords: SIS-mixer ; millimetre-waves ; imaging arrays ; quasi-opticalSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The construction of SIS heterodyne imaging arrays for submillimetre wave-lengths requires multiple coupling of the local oscillator signal. The quasi-optical analogue of a multiple cross-guide coupler, employing 45° beam-splitters successively stacked along the local oscillator beam, allows for individual adjustment of local oscillator power to each channel. We analyse the coupling as a function of the focal ratio of the incident beams and the number of beam widths off-axis through which the coupler is extended, and describe a simple construction method to realise a compact and effective design.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1572-9559Keywords: SIS-mixer ; millimetre-waves ; quantum mixer theory ; embedding impedanceSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Tucker's quantum theory of mixing (in the 3-port approximation) is employed with Eisenhart and Khan's equivalent circuit for a junction mounted in waveguide to predict the gain of an SIS mixer as a function of guide impedance, series inductance, junction capacitance, IF load impedance and backshort loos. The improvements which will result from optimisation of these parameters are quantified. It is shown that for optimum performance a backshort VSWR〉100 is required, which is hard to realise at high frequenciesType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1572-9559Keywords: SIS-mixer ; SIN-mixer ; millimetre-waves ; quantum mixer theorySource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Tucker's quantum theory of mixing (in the 3-port approximation) is employed to calculate the gain over a wide range of frequencies of model mixers employing SIS and SIN junctions with both real and idealI–V characteristics. A comparison is made between the performance of junctions in waveguide and open antenna mounts. It is concluded that ideal junctions give gain 1.5 to 2 times higher than real ones, SIS junctions have gain approximately three times greater than otherwise similar SIN junctions, and that junction areas need to be typically three times smaller in open antenna structures to provide comparable gain to those in waveguide mounts.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1572-9559Keywords: SIS-mixer ; quasiparticle mixer ; millimetre wavesSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We describe the design and performance of a 210–280 GHz SIS heterodyne receiver built for use on the Maxwell Telescope. The mixer utilises a lead alloy SIS tunnel junction, mounted in 4∶1 reduced height rectangular waveguide, and is tuned with a backshort in 2∶1 reduced height guide. The receiver has a receiver noise temperature of 〈200K (DSB) across the RF band from 210–270 GHz, with a best noise temperature measured in the laboratory of 113K (DSB) at 231 GHz. A prototype version of this receiver was successfully operated on the telescope in May 1989. By direct intercalibration with a Schottky diode receiver we deduced a best receiver noise temperature of 140K (DSB) at 245 GHz. Discrepancies between this figure and that derived from broad band thermal load calibration are discussed in the accompanying paper (Little et al., 1992, this issue).Type of Medium: Electronic ResourceURL: