Search Results - (Author, Cooperation:L. Guarente)
-
1Latest Papers from Table of Contents or Articles in PressC. M. Metallo ; P. A. Gameiro ; E. L. Bell ; K. R. Mattaini ; J. Yang ; K. Hiller ; C. M. Jewell ; Z. R. Johnson ; D. J. Irvine ; L. Guarente ; J. K. Kelleher ; M. G. Vander Heiden ; O. Iliopoulos ; G. Stephanopoulos
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-11-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetyl Coenzyme A/biosynthesis/metabolism ; Aryl Hydrocarbon Receptor Nuclear Translocator/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics/metabolism ; CD8-Positive T-Lymphocytes/cytology ; Carbon/metabolism ; Carcinoma, Renal Cell/metabolism/pathology ; *Cell Hypoxia ; Cell Line, Tumor ; Cells, Cultured ; Citric Acid Cycle ; Glutamine/*metabolism ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Isocitrate Dehydrogenase/deficiency/genetics/*metabolism ; Ketoglutaric Acids/metabolism ; Kidney Neoplasms/metabolism/pathology ; *Lipogenesis ; Oxidation-Reduction ; Oxygen/metabolism ; Palmitic Acid/metabolism ; Von Hippel-Lindau Tumor Suppressor Protein/genetics/metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2011-09-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Caenorhabditis elegans/*physiology ; *Caenorhabditis elegans Proteins ; Female ; Histone Deacetylases/*genetics ; Male ; *Silent Information Regulator Proteins, Saccharomyces cerevisiae ; Trans-Activators/*geneticsPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] The yeast Sir protein complex has been implicated in transcriptional silencing and suppression of recombination. The Sir complex creates structured chromosomal domains at telomeres, silent mating-type loci and ribosomal DNA to invoke these functional states. Mechanistic insights into the ...Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0168-9525Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0168-9525Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0168-9525Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0168-9525Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1432-0983Keywords: Saccharomyces cerevisiae ; Cytochrome c ; Regulatory geneSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary The CYP1 gene has previously been identified as coding for a positive trans active factor that activates the expression of CYC1 and CYP3, which are the structural genes for isol- and iso2-cytochrome c. Two phenotypically distinct classes of CYP1 mutations can be obtained indicating that CYC1 and CYP3 are differentially regulated by the product of CYP1. The HAP1 gene codes for a product which has previously been proved to be necessary for the expression of the heme dependent CYC1-UAS1 cis regulatory sequence. In this article, we show by complementation and recombination that CYP1 and HAP1 are the same gene, moreover we identify hap1-1 as an iso2-cytochrome c underproducer mutation of the CYP1 gene.Type of Medium: Electronic ResourceURL: