Search Results - (Author, Cooperation:J. Mackey)
-
1T. F. Mackay ; S. Richards ; E. A. Stone ; A. Barbadilla ; J. F. Ayroles ; D. Zhu ; S. Casillas ; Y. Han ; M. M. Magwire ; J. M. Cridland ; M. F. Richardson ; R. R. Anholt ; M. Barron ; C. Bess ; K. P. Blankenburg ; M. A. Carbone ; D. Castellano ; L. Chaboub ; L. Duncan ; Z. Harris ; M. Javaid ; J. C. Jayaseelan ; S. N. Jhangiani ; K. W. Jordan ; F. Lara ; F. Lawrence ; S. L. Lee ; P. Librado ; R. S. Linheiro ; R. F. Lyman ; A. J. Mackey ; M. Munidasa ; D. M. Muzny ; L. Nazareth ; I. Newsham ; L. Perales ; L. L. Pu ; C. Qu ; M. Ramia ; J. G. Reid ; S. M. Rollmann ; J. Rozas ; N. Saada ; L. Turlapati ; K. C. Worley ; Y. Q. Wu ; A. Yamamoto ; Y. Zhu ; C. M. Bergman ; K. R. Thornton ; D. Mittelman ; R. A. Gibbs
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-02-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Centromere/genetics ; Chromosomes, Insect/genetics ; Drosophila melanogaster/*genetics ; *Genome-Wide Association Study ; *Genomics ; Genotype ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/*genetics ; Selection, Genetic/genetics ; Starvation/genetics ; Telomere/genetics ; X Chromosome/geneticsPublished by: -
2S. P. Shah ; A. Roth ; R. Goya ; A. Oloumi ; G. Ha ; Y. Zhao ; G. Turashvili ; J. Ding ; K. Tse ; G. Haffari ; A. Bashashati ; L. M. Prentice ; J. Khattra ; A. Burleigh ; D. Yap ; V. Bernard ; A. McPherson ; K. Shumansky ; A. Crisan ; R. Giuliany ; A. Heravi-Moussavi ; J. Rosner ; D. Lai ; I. Birol ; R. Varhol ; A. Tam ; N. Dhalla ; T. Zeng ; K. Ma ; S. K. Chan ; M. Griffith ; A. Moradian ; S. W. Cheng ; G. B. Morin ; P. Watson ; K. Gelmon ; S. Chia ; S. F. Chin ; C. Curtis ; O. M. Rueda ; P. D. Pharoah ; S. Damaraju ; J. Mackey ; K. Hoon ; T. Harkins ; V. Tadigotla ; M. Sigaroudinia ; P. Gascard ; T. Tlsty ; J. F. Costello ; I. M. Meyer ; C. J. Eaves ; W. W. Wasserman ; S. Jones ; D. Huntsman ; M. Hirst ; C. Caldas ; M. A. Marra ; S. Aparicio
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-04-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Breast Neoplasms/diagnosis/*genetics/*pathology ; Clone Cells/metabolism/pathology ; DNA Copy Number Variations/genetics ; DNA Mutational Analysis ; Disease Progression ; *Evolution, Molecular ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/genetics ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; INDEL Mutation/genetics ; Mutation/*genetics ; Point Mutation/genetics ; Precision Medicine ; Reproducibility of Results ; Sequence Analysis, RNAPublished by: -
3J. Mackey ; S. Mohamed ; V. V. Gvaramadze ; R. Kotak ; N. Langer ; D. M. Meyer ; T. J. Moriya ; H. R. Neilson
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Natalie M. Mahowald; Douglas S. Hamilton; Katherine R. M. Mackey; J. Keith Moore; Alex R. Baker; Rachel A. Scanza; Yan Zhang
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-07-06Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
5Staff View
ISSN: 1365-4632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: : In dermatology, patients with nodosum leprosum and discoid lupus erythematosus are benefited by clofazi-mine therapy. Its use in other autoimmune diseases has to be considered. Patients with lupus pernio may respond to this regime, but further prolonged trials will have to be undertaken.Type of Medium: Electronic ResourceURL: -
6Akpati, H. C. ; Mackey, J. ; Nordlander, P. ; Lou, L.
College Park, Md. : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Ammonia chemisorption on a small and positively charged gallium arsenide cluster in the gas phase has been investigated using density-functional methods. The reactivity at various cluster sites are characterized in terms of binding energy and charge transfer from the adsorbate to the cluster with a strong correlation shown between the latter two quantities. The calculations show a strong dependence of the reactivity of the cluster on its charge state. Ionizing the bare cluster to a cationic charge state enables multiple chemisorption of ammonia, which is much less favored by a neutral cluster and can be prohibited on a negatively charged cluster. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
7Mackey, J. ; Lou, L. ; Nordlander, P. ; Smalley, R. E.
College Park, Md. : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: It is well known that the chemical reactivity of small gallium–arsenide clusters can be sensitive to cluster size and geometrical structure. We have performed ab initio calculations probing the interaction of NH3 with different sites of a free Ga5As5 cluster. Our results show that bonding tends to be strongest at gallium sites. Adsorption of NH3 is found to induce strong relaxation of the cluster global geometry. The cluster sites are compared with sites on the (111) bulk surface of gallium arsenide, and the possibility for exploring the similarity between cluster reactivity and surface reactivity is discussed.Type of Medium: Electronic ResourceURL: -
8Mackey, J. ; Lou, L. ; Nordlander, P.
College Park, Md. : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: We present an investigation of the interaction of two ammonia molecules with the Ga5As5 cluster. The (NH3)2Ga5As5 complex is found to be stable, in agreement with experiments. We find a significant decrease in the binding energy for the second ammonia, compared to single ammonia adsorption in agreement with experimental results. We investigate the site dependence of the ammonia–ammonia interaction and demonstrate that the adsorption of a single ammonia on certain sites prevents further adsorption of ammonia on certain other sites. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: An effective method for reducing the formation of curd in canned salmon is described. The process consists of applying an aqueous extract of papaya latex powder to the surfaces of raw salmon segments prior to conventional vacuum seaming and heat sterilization. It is based on the idea that large curd-forming proteins, once reduced to peptide and polypeptide fragments, will no longer coagulate when heated. A substantial reduction in curd formation was achieved in canned coho and sockeye salmon.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0003-2697Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0022-5185Topics: Theology and Religious StudiesNotes: AUTHORS AND BOOKS REVIEWED OR NOTICEDURL: -
12GRIME, J. P. ; MACKEY, J. M. ; HILLIER, S. H. ; READ, D. J.
[s.l.] : Nature Publishing Group
Published 1988Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] GRIME ET AL. REPLY-In grasslands on shallow calcareous soils, grazing has long been implicated as a control on plant species diversity, but the widespread occurrence of mycorrhizal infection in plants growing in such situations has been largely ignored. The objective of our experiment was to ...Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] We have studied nucleoside 5'-diphosphates and the enzyme, polynucleotide phosphorylase, which catalyses the successive transfer of the nucleoside 5'-phosphoryl moiety from the substrate to the 3'-hydroxyl group of a polyribonucleotide chain. A number of nucleotide 5'-diphosphates containing ...Type of Medium: Electronic ResourceURL: -
14MOLSON, G. R. ; MACKEY, J. A. ; SMART, J. V. ; TURNER, PAUL
[s.l.] : Nature Publishing Group
Published 1966Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] An investigation has been carried out into the effect of promethazine hydrochloride ('Phenergan') on visuo-motor co-ordination. The apparatus consisted of a rotating drum (1 rotation/ 53 sec) covered with an insulating layer in which 400 holes had been cut. On the 'disk-dotting' principle, and ...Type of Medium: Electronic ResourceURL: -
15Grime, J. P. ; Mackey, J. M. L. ; Hillier, S. H. ; Read, D. J.
[s.l.] : Nature Publishing Group
Published 1987Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] In the humped-back model1'5'6 explaining patterns of variation in species richness in herbaceous vegetation, it is suggested that the potential for high diversity is restricted to a corridor which, in the British Isles, corresponds to the range 350-750 g dry weight m~2 in seasonal maximum in ...Type of Medium: Electronic ResourceURL: -
16Hawkins, C. ; Treffry, A. ; Mackey, J. B. ; Williams, J. M. ; Andrews, S. C. ; Guest, J. R. ; Harrison, P. M.
Springer
Published 1996Staff ViewISSN: 0392-6737Keywords: Mössbauer effect ; other γ-ray spectroscopy ; Other topics in biophysics and medical physics ; Conference proceedingsSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Summary This paper describes a preliminary investigation of the mechanisms of Fe(II) oxidation and storage of Fe(III) in the bacterioferritin ofEscherichia coli (EcBFR). Using Mössbauer spectroscopy to examine the initial oxidation of iron by EcBFR we have confirmed that this ferritin exhibits «ferroxidase» activity and have shown that dimeric and monomeric iron species are produced as intermediates. We compare the characteristics of ferroxidase activity in EcBFR with those of human H-chain ferritin (HuHF) and discuss the different Mössbauer parameters of their dimeric iron with reference to the structures of their di-metal sites. In addition, we present preliminary findings suggesting that after an initial «burst», the rate of oxidation is greatly reduced, possibly due to blockage of the ferroxidase centre by bound iron. A new component, not found in HuHF and probably representing a small cluster of Fe(III) atoms, is reported.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1432-1939Keywords: Resource competition ; Resource foraging ; Dominance ; Plasticity ; Dry matter allocationSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary There is widespread uncertainty about the nature and role of morphological plasticity in resource competition in plant communities. We have assayed the foraging characteristics of leaf canopies and root systems of eight herbaceous plants of contrasted ecology using new techniques to create controlled patchiness in light and mineral nutrient supply. The results are compared with those of a conventional competition experiment. Measurements of dry matter partitioning and growth in patchy conditions indicate a consistent positive association between the foraging characteristics of roots and shoots, supporting the hypothesis of strong interdependence of competitive abilities for light and mineral nutrients. Differences are identified in the abilities of dominant and subordinate plants to forage on coarse and fine scalcs. It is suggested that a trade-off exists in the scale (“high” in dominants) and precision (high in subordinates) with which resources are intercepted and that this trade-off contributes to diversity in communities of competing plants.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1432-1017Keywords: Key words Human liver ; Human brain ; Ferritin ; Electron microscopy ; Mössbauer spectroscopySource: Springer Online Journal Archives 1860-2000Topics: BiologyPhysicsNotes: Abstract Human brain (globus pallidus) and liver tissues were investigated by means of electron microscopy (EM), Mössbauer spectroscopy (MS) and SQUID magnetometry techniques. Based on MS measurements, the iron present was identified to be in the ferritin-like form (61–88%) and in the form of a low-spin iron species (the balance). Its overall concentration was estimated as 1.5(3) mg in the brain and 2.4(5) mg in the liver, per gram of lyophilized tissue. The average core diameter was determined by EM measurements to be equal to 7.5(1.3) nm for the liver and 3.3(5) nm for the brain. Magnetization measurements carried out between 5 and 300 K yielded an estimation of an average blocking temperature, KT BL, as equal to 6.7 K and 8.5 K for the liver and the brain, respectively. From the dependence of KT BL on the external magnetic field it was concluded that the ferritin-like cores in the studied samples can be regarded as non-interacting particles. Finally, the uniaxial magnetic anisotropy constant was determined to be 6×103 J/m3 for the liver and 4×104 J/m3 for the brain.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1432-2242Source: Springer Online Journal Archives 1860-2000Topics: BiologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1432-2242Source: Springer Online Journal Archives 1860-2000Topics: BiologyType of Medium: Electronic ResourceURL: