Search Results - (Author, Cooperation:J. Heitman)

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  1. 1
    D. Floudas ; M. Binder ; R. Riley ; K. Barry ; R. A. Blanchette ; B. Henrissat ; A. T. Martinez ; R. Otillar ; J. W. Spatafora ; J. S. Yadav ; A. Aerts ; I. Benoit ; A. Boyd ; A. Carlson ; A. Copeland ; P. M. Coutinho ; R. P. de Vries ; P. Ferreira ; K. Findley ; B. Foster ; J. Gaskell ; D. Glotzer ; P. Gorecki ; J. Heitman ; C. Hesse ; C. Hori ; K. Igarashi ; J. A. Jurgens ; N. Kallen ; P. Kersten ; A. Kohler ; U. Kues ; T. K. Kumar ; A. Kuo ; K. LaButti ; L. F. Larrondo ; E. Lindquist ; A. Ling ; V. Lombard ; S. Lucas ; T. Lundell ; R. Martin ; D. J. McLaughlin ; I. Morgenstern ; E. Morin ; C. Murat ; L. G. Nagy ; M. Nolan ; R. A. Ohm ; A. Patyshakuliyeva ; A. Rokas ; F. J. Ruiz-Duenas ; G. Sabat ; A. Salamov ; M. Samejima ; J. Schmutz ; J. C. Slot ; F. St John ; J. Stenlid ; H. Sun ; S. Sun ; K. Syed ; A. Tsang ; A. Wiebenga ; D. Young ; A. Pisabarro ; D. C. Eastwood ; F. Martin ; D. Cullen ; I. V. Grigoriev ; D. S. Hibbett
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-06-30
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Basidiomycota/classification/*enzymology/*genetics ; Bayes Theorem ; *Evolution, Molecular ; *Genome, Fungal ; Indoles ; Lignin/*metabolism ; Peroxidases/*genetics/metabolism ; Wood/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-08-01
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Calcineurin/genetics/metabolism ; Calcineurin Inhibitors ; Drug Resistance, Fungal/*genetics ; Epigenesis, Genetic/*genetics ; Humans ; Hyphae/drug effects/genetics/growth & development ; Molecular Sequence Data ; Mucor/*drug effects/*genetics/growth & development ; Mucormycosis/drug therapy/microbiology ; Mutation/*genetics ; Phenotype ; *RNA Interference ; Tacrolimus/metabolism/*pharmacology ; Tacrolimus Binding Protein 1A/deficiency/genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Heitman, J. ; Model, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-1119
    Keywords:
    DNA damage ; DNA double-strand breaks ; DNA metabolism ; DNA methyltransferases ; DNA repair ; DNA-binding proteins ; EcoRI endonuclease ; Escherichia coli ; SOS response ; methylation-dependent restriction ; restriction-modification
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(91)90383-M

    Articles: DFG German National Licenses
  4. 4
    Roth, C., Sun, S., Billmyre, R. B., Heitman, J., Magwene, P. M.
    Genetics Society of America (GSA)
    Published 2018
    Staff View
    Publication Date:
    2018-05-30
    Publisher:
    Genetics Society of America (GSA)
    Print ISSN:
    0016-6731
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-06-01
    Publisher:
    Genetics Society of America (GSA)
    Electronic ISSN:
    2160-1836
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2018-04-05
    Publisher:
    Genetics Society of America (GSA)
    Print ISSN:
    0016-6731
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Fu, C., Donadio, N., Cardenas, M. E., Heitman, J.
    Genetics Society of America (GSA)
    Published 2018
    Staff View
    Publication Date:
    2018-01-30
    Publisher:
    Genetics Society of America (GSA)
    Print ISSN:
    0016-6731
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2018-02-09
    Publisher:
    Genetics Society of America (GSA)
    Electronic ISSN:
    2160-1836
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Garcia-Bustos, J. ; Heitman, J. ; Hall, M.N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0304-4157
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0304-4157(91)90013-M

    Articles: DFG German National Licenses
  10. 10
    Heitman, J. ; Fulford, W. ; Model, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-1119
    Keywords:
    EcoRI endonuclease ; Escherichia coli ; M13mp18 vector ; Recombinant DNA ; filamentous phage ; regulated gene expression ; restriction-modification ; toxic proteins
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(89)90480-0

    Articles: DFG German National Licenses
  11. 11
    Heitman, J. ; Koller, A. ; Cardenas, M.E. ; Hall, M.N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    1046-2023
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/meth.1993.1022

    Articles: DFG German National Licenses
  12. 12
    Hemenway, C. S. ; Heitman, J.
    Springer
    Published 1999
    Staff View
    ISSN:
    1617-4623
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The target of the immunosuppressants cyclosporin A(CsA) and FK506 is calcineurin, a highly conserved protein phosphatase that is required for T-cell activation and the regulation of ion homeostasis in yeast. Here we identify two genes, PMR2B and LIC4 which, when overexpressed, suppress the cation-sensitive phenotype of yeast cells lacking calcineurin. PMR2B encodes a Na+/Li+-specific plasma membrane pump and is similar to PMR2A, whose expression is known to be regulated by calcineurin. LIC4 (lithium comvertas) encodes a novel 33-kDa protein with no identity to known proteins. LIC4 overexpression suppresses the Li+-sensitive phenotype of calcineurin mutants but not the defect in recovery from pheromone arrest or viability of calcineurin dependent mutants, indicating a specific role in cation homeostasis. Similarly, lic4 mutations increase the Li+ sensitivity of both wild-type and calcineurin mutant strains, and reduce expression of pmr2A in calcineurin mutant strains, indicating that calcineurin and Lic4 may regulate parallel cation homeostatic pathways. lic4 mutations also exacerbate the Li+-sensitive phenotype of hal3 mutant strains, and overexpression of either Lic4 or Hal3 suppresses the salt sensitivity of mutant strains lacking calcineurin, Hal3, or Lic4, either singly or in combination. Taken together, these observations suggest that calcineurin, Hal3, and Lic4 cooperatively regulate the response of yeast cells to␣cation stress. Lic4 is phosphoprotein in vivo and a calcineurin substrate in vitro. By indirect and direct immunofluorescence detection of HA- and GFP-tagged proteins, Lic4 is localized in the nucleus in wild-type cells but predominantly cytoplasmic in cells lacking calcineurin. Taken together, our findings support a model in which calcineurin and Lic4 are components of signalling cascades that regulate cation stress responses in yeast.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004380050980

    Articles: DFG German National Licenses