Search Results - (Author, Cooperation:J. Gorham)
-
1J. T. Hinson ; A. Chopra ; N. Nafissi ; W. J. Polacheck ; C. C. Benson ; S. Swist ; J. Gorham ; L. Yang ; S. Schafer ; C. C. Sheng ; A. Haghighi ; J. Homsy ; N. Hubner ; G. Church ; S. A. Cook ; W. A. Linke ; C. S. Chen ; J. G. Seidman ; C. E. Seidman
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-09-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adrenergic beta-Agonists/pharmacology ; Cardiomyopathy, Dilated/*genetics/pathology/*physiopathology ; Cells, Cultured ; Connectin/chemistry/*genetics/*physiology ; Heart Rate ; Humans ; Induced Pluripotent Stem Cells/*physiology ; Isoproterenol/pharmacology ; Mutant Proteins/chemistry/physiology ; *Mutation, Missense ; Myocardial Contraction ; Myocytes, Cardiac/*physiology ; RNA/genetics/metabolism ; Sarcomeres/*physiology/ultrastructure ; Sequence Analysis, RNA ; Signal Transduction ; Stress, PhysiologicalPublished by: -
2De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomaliesJ. Homsy ; S. Zaidi ; Y. Shen ; J. S. Ware ; K. E. Samocha ; K. J. Karczewski ; S. R. DePalma ; D. McKean ; H. Wakimoto ; J. Gorham ; S. C. Jin ; J. Deanfield ; A. Giardini ; G. A. Porter, Jr. ; R. Kim ; K. Bilguvar ; F. Lopez-Giraldez ; I. Tikhonova ; S. Mane ; A. Romano-Adesman ; H. Qi ; B. Vardarajan ; L. Ma ; M. Daly ; A. E. Roberts ; M. W. Russell ; S. Mital ; J. W. Newburger ; J. W. Gaynor ; R. E. Breitbart ; I. Iossifov ; M. Ronemus ; S. J. Sanders ; J. R. Kaltman ; J. G. Seidman ; M. Brueckner ; B. D. Gelb ; E. Goldmuntz ; R. P. Lifton ; C. E. Seidman ; W. K. Chung
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Brain/abnormalities/metabolism ; Child ; Congenital Abnormalities/genetics ; Exome/genetics ; Heart Defects, Congenital/*diagnosis/*genetics ; Humans ; Mutation ; Nervous System Malformations/*genetics ; Neurogenesis/*genetics ; Prognosis ; RNA Splicing/genetics ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transcription, GeneticPublished by: -
3P. W. Gorham, J. Bynes, B. Fox, C. Hast, B. Hill, K. Jobe, C. Miki, R. Prechelt, B. Rotter, D. P. Saltzberg, S. A. Wissel, G. S. Varner, and S. Zekioglu
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-07-13Publisher: American Physical Society (APS)Electronic ISSN: 1098-4402Topics: PhysicsKeywords: Particle and Radiation DetectorsPublished by: -
4Staff View
ISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Abstract Salt excretion by glands on the leaves of Leptochloa fusca was studied. The rate of excretion was strongly dependent on temperature up to 39°C, which is near the optimum for photosynthesis in this thermophilic C4 grass. The concentration of salt in the xylem required to sustain the observed rate of excretion was low (about two orders of magnitude less than the external concentration). Salt excretion is concluded to be a secondary mechanism of salt tolerance, with exclusion at the roots being the major mechanism. The rate of salt excretion was strongly dependent on temperature.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Abstract The chemical compositions of a number of halophytes from salt marshes on Ynys Môn (Anglesey), Wales, and of some related mesophytes and sand dune plants have been determined. Analyses of the inorganic ions broadly confirmed the existence of a characteristic chemical composition of many monoco-tyledonous salt-marsh plants in that they contain high levels of potassium and relatively low levels of sodium. In contrast to most dicotyledonous halophytes, especially members of the Chenopodiacease, the monocots restrict the entry of inorganic ions and use high levels of soluble sugars to maintain an adequate solute potential. Low calcium levels were not found to be a feature of these plants, as was previously reported. The large amounts of sugars found in the monocotyle-donous plants suggested that they must be located mainly in the vacuoles, in contrast to glycinebetaine which is thought to accumulate principally in the cytoplasm of the salt accumulating Chenopodiaceae. The monocotyledonous halophytes which accumulate proline differ from the normal monocotyledonous physiotype in the accumulation of larger quantities of sodium. Triglochin maritima is one species of this type, and Puccinellia maritima a less extreme example. Spartina spp. accumulating glycinebetaine and β-dimethyl-sulphoniopropionate also have unusually high inorganic ion contents for monocots. Several salt marsh plants contained large quantities of amino acids other than proline. As with ionic composition, the nature of the organic solutes broadly followed taxonomic lines. The usefulness of the physiotype concept is discussed.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The main objective of this work is to demonstrate the expression of salt tolerance genes in a wheat-Agropyron amphiploid. Salt tolerance tests were carried out on wheat varieties, ‘Chinese Spring,’ and ‘Glenn-son 81’ the amphiploid between ‘Chinese Spring’ and A. junceum, A. junceum and amphiploid × wheat hybrids, Apart from germination in petridishes all other tests were carried out on plants grown in saline hydroculture tanks. Fresh weight measurements are given for stressed and non-stressed plants as well as measurements of harvest ripe plants. The utility of A. junceum as a source of salt tolerance genes for wheat is discussed.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0031-9422Keywords: Conocephalum conicum ; Lunularia cruciata ; liverwort ; lunularic acid ; lunularic acid decarboxylase. ; lunularinSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0031-9422Keywords: Algae ; Hepaticae ; Hydrangea macrophylla ; Saxifragaceae ; bibenzyls ; chemotaxonomy. ; liverworts ; lunularic acid ; lunularin ; stilbenesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0031-9422Keywords: Chenopodiaceae ; Spinacia oleracea ; bibenzyls ; chloroplasts ; lunularic acid ; photosynthesis ; pinosylvin. ; stilbenesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0031-9422Keywords: IAA-oxidase. ; Lunularia ; Marchantia ; bibenzyls ; growth inhibitors ; liverworts ; lunularic acid ; stilbenesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0003-2670Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0272-7714Keywords: Cladophora rupestris ; North Wales ; amino acids ; fluctuating salinity ; glycine betaine ; inorganic ions ; turgor pressureSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyGeographyGeosciencesType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: A study was made of the effects of salinity on the concentrations of free sugars, glycinebetaine, proline and other chemical components of Aster tripolium L., Daucus carota L., Honkenya peploides (L.) Ehr. and Plantago coronopus L. (Dicotyledones); and Carex extensa Good., Eleocharis uniglumis (Link) Schutt., Juncus maritima Lam. and Schoenoplectus tabernaemontani (C. C. Gmel.) Palla (Monocotyledones) grown in the laboratory. In Plantago coronopus the level of the polyol sorbitol increased when the plants were subjected to NaCl stress, while in Honkenya peploides the cyclitol pinitol accumulated. No consistent pattern emerged with respect to the changes in free sugar contents in either the monocotyledonous or dicotyledonous plants, though the monocotyledonous plants generally had higher sugar contents.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Ninety four percent of the genome of bovine herpesvirus 4 (BHV-4) strain DN 599 was cloned and a physical map was constructed by Southern blot analysis using a library of cloned fragments cleaved with the 3 restriction enzymes (Eco RI, Bam HI, and Hin dIII). The genome length was estimated to be 156.5 kbp±0.7. The genome comprises a region of unique segment (114 kbp) and two flanking segments containing tandem repeats. The size of each repeat was approximately 2.35 kbp and each repeat contained one Eco RI site and two Bam HI sites. We also examined two recent American field-isolates of BHV-4 and compared the Eco RI maps of the two isolates with that of DN 599. We observed the following: (1) insertions or deletions of restriction sites at the periphery of the unique segment; (2) variation in the lengths of junction fragments; (3) variations in the lengths of hypermolar Eco RI fragments containing the repeats; and (4) the Eco RI map of one of the American field-isolates resembles the BHV-4 “Movar type” of Europe.Type of Medium: Electronic ResourceURL: -
20Tsujimoto, Y. ; Jaffe, E. ; Cossman, J. ; Gorham, J. ; Nowell, P. C. ; Croce, C. M.
[s.l.] : Nature Publishing Group
Published 1985Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Our previous analysis of the breakpoint between chromosomes 11 and 14 in one case of B-CLL (CLL 271) indicated that it occurred in the joining ( J) region6 of the heavy-chain locus5 on chromosome 14. Chromosome 11-derived DNA sequences close to the breakpoint in the CLL 271 cells were then used to ...Type of Medium: Electronic ResourceURL: