Search Results - (Author, Cooperation:J. C. Spence)

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  1. 1
    Staff View
    Publication Date:
    2013-12-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Crystallography, X-Ray/*instrumentation/*methods ; Humans ; Lasers ; Protein Conformation ; Receptor, Serotonin, 5-HT2B/chemistry/radiation effects ; Receptors, G-Protein-Coupled/*chemistry/radiation effects ; Time Factors
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-12-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Catalytic Domain ; Cathepsin B/antagonists & inhibitors/*chemistry ; Crystallization ; Crystallography, X-Ray ; Enzyme Precursors/chemistry ; Glycosylation ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Protozoan Proteins/antagonists & inhibitors/*chemistry ; Sf9 Cells ; Spodoptera ; Trypanosoma brucei brucei/*enzymology ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-12-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacterial Proteins/chemistry/*ultrastructure ; Crystallography, X-Ray/*methods ; Photoreceptors, Microbial/chemistry/*ultrastructure ; Protein Conformation ; Time Factors
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2016-05-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    S. Boutet ; L. Lomb ; G. J. Williams ; T. R. Barends ; A. Aquila ; R. B. Doak ; U. Weierstall ; D. P. DePonte ; J. Steinbrener ; R. L. Shoeman ; M. Messerschmidt ; A. Barty ; T. A. White ; S. Kassemeyer ; R. A. Kirian ; M. M. Seibert ; P. A. Montanez ; C. Kenney ; R. Herbst ; P. Hart ; J. Pines ; G. Haller ; S. M. Gruner ; H. T. Philipp ; M. W. Tate ; M. Hromalik ; L. J. Koerner ; N. van Bakel ; J. Morse ; W. Ghonsalves ; D. Arnlund ; M. J. Bogan ; C. Caleman ; R. Fromme ; C. Y. Hampton ; M. S. Hunter ; L. C. Johansson ; G. Katona ; C. Kupitz ; M. Liang ; A. V. Martin ; K. Nass ; L. Redecke ; F. Stellato ; N. Timneanu ; D. Wang ; N. A. Zatsepin ; D. Schafer ; J. Defever ; R. Neutze ; P. Fromme ; J. C. Spence ; H. N. Chapman ; I. Schlichting
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-06-02
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Crystallography, X-Ray/*methods ; Lasers ; Muramidase/chemistry/radiation effects ; *Protein Conformation
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Y. Kang ; X. E. Zhou ; X. Gao ; Y. He ; W. Liu ; A. Ishchenko ; A. Barty ; T. A. White ; O. Yefanov ; G. W. Han ; Q. Xu ; P. W. de Waal ; J. Ke ; M. H. Tan ; C. Zhang ; A. Moeller ; G. M. West ; B. D. Pascal ; N. Van Eps ; L. N. Caro ; S. A. Vishnivetskiy ; R. J. Lee ; K. M. Suino-Powell ; X. Gu ; K. Pal ; J. Ma ; X. Zhi ; S. Boutet ; G. J. Williams ; M. Messerschmidt ; C. Gati ; N. A. Zatsepin ; D. Wang ; D. James ; S. Basu ; S. Roy-Chowdhury ; C. E. Conrad ; J. Coe ; H. Liu ; S. Lisova ; C. Kupitz ; I. Grotjohann ; R. Fromme ; Y. Jiang ; M. Tan ; H. Yang ; J. Li ; M. Wang ; Z. Zheng ; D. Li ; N. Howe ; Y. Zhao ; J. Standfuss ; K. Diederichs ; Y. Dong ; C. S. Potter ; B. Carragher ; M. Caffrey ; H. Jiang ; H. N. Chapman ; J. C. Spence ; P. Fromme ; U. Weierstall ; O. P. Ernst ; V. Katritch ; V. V. Gurevich ; P. R. Griffin ; W. L. Hubbell ; R. C. Stevens ; V. Cherezov ; K. Melcher ; H. E. Xu
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Arrestin/*chemistry/*metabolism ; Binding Sites ; Crystallography, X-Ray ; Disulfides/chemistry/metabolism ; Humans ; Lasers ; Mice ; Models, Molecular ; Multiprotein Complexes/biosynthesis/chemistry/metabolism ; Protein Binding ; Reproducibility of Results ; Rhodopsin/*chemistry/*metabolism ; Signal Transduction ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2016-02-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Crystallization ; Crystallography, X-Ray/*methods ; Models, Molecular ; Photosystem II Protein Complex/*chemistry
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    C. Kupitz ; S. Basu ; I. Grotjohann ; R. Fromme ; N. A. Zatsepin ; K. N. Rendek ; M. S. Hunter ; R. L. Shoeman ; T. A. White ; D. Wang ; D. James ; J. H. Yang ; D. E. Cobb ; B. Reeder ; R. G. Sierra ; H. Liu ; A. Barty ; A. L. Aquila ; D. Deponte ; R. A. Kirian ; S. Bari ; J. J. Bergkamp ; K. R. Beyerlein ; M. J. Bogan ; C. Caleman ; T. C. Chao ; C. E. Conrad ; K. M. Davis ; H. Fleckenstein ; L. Galli ; S. P. Hau-Riege ; S. Kassemeyer ; H. Laksmono ; M. Liang ; L. Lomb ; S. Marchesini ; A. V. Martin ; M. Messerschmidt ; D. Milathianaki ; K. Nass ; A. Ros ; S. Roy-Chowdhury ; K. Schmidt ; M. Seibert ; J. Steinbrener ; F. Stellato ; L. Yan ; C. Yoon ; T. A. Moore ; A. L. Moore ; Y. Pushkar ; G. J. Williams ; S. Boutet ; R. B. Doak ; U. Weierstall ; M. Frank ; H. N. Chapman ; J. C. Spence ; P. Fromme
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Crystallography, X-Ray ; Cyanobacteria/*chemistry ; *Models, Molecular ; Photosystem II Protein Complex/*chemistry ; Protein Structure, Tertiary
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    H. N. Chapman ; P. Fromme ; A. Barty ; T. A. White ; R. A. Kirian ; A. Aquila ; M. S. Hunter ; J. Schulz ; D. P. DePonte ; U. Weierstall ; R. B. Doak ; F. R. Maia ; A. V. Martin ; I. Schlichting ; L. Lomb ; N. Coppola ; R. L. Shoeman ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; P. Holl ; M. Liang ; M. Barthelmess ; C. Caleman ; S. Boutet ; M. J. Bogan ; J. Krzywinski ; C. Bostedt ; S. Bajt ; L. Gumprecht ; B. Rudek ; B. Erk ; C. Schmidt ; A. Homke ; C. Reich ; D. Pietschner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; M. Messerschmidt ; J. D. Bozek ; S. P. Hau-Riege ; M. Frank ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; G. J. Williams ; J. Hajdu ; N. Timneanu ; M. M. Seibert ; J. Andreasson ; A. Rocker ; O. Jonsson ; M. Svenda ; S. Stern ; K. Nass ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; K. E. Schmidt ; X. Wang ; I. Grotjohann ; J. M. Holton ; T. R. Barends ; R. Neutze ; S. Marchesini ; R. Fromme ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; I. Andersson ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; J. C. Spence
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-02-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Crystallography, X-Ray/instrumentation/*methods ; Lasers ; Models, Molecular ; Nanoparticles/*chemistry ; Nanotechnology/instrumentation/*methods ; Photosystem I Protein Complex/*chemistry ; Protein Conformation ; Time Factors ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  10. 10
    M. M. Seibert ; T. Ekeberg ; F. R. Maia ; M. Svenda ; J. Andreasson ; O. Jonsson ; D. Odic ; B. Iwan ; A. Rocker ; D. Westphal ; M. Hantke ; D. P. DePonte ; A. Barty ; J. Schulz ; L. Gumprecht ; N. Coppola ; A. Aquila ; M. Liang ; T. A. White ; A. Martin ; C. Caleman ; S. Stern ; C. Abergel ; V. Seltzer ; J. M. Claverie ; C. Bostedt ; J. D. Bozek ; S. Boutet ; A. A. Miahnahri ; M. Messerschmidt ; J. Krzywinski ; G. Williams ; K. O. Hodgson ; M. J. Bogan ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; I. Andersson ; S. Bajt ; M. Barthelmess ; J. C. Spence ; P. Fromme ; U. Weierstall ; R. Kirian ; M. Hunter ; R. B. Doak ; S. Marchesini ; S. P. Hau-Riege ; M. Frank ; R. L. Shoeman ; L. Lomb ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; C. Schmidt ; L. Foucar ; N. Kimmel ; P. Holl ; B. Rudek ; B. Erk ; A. Homke ; C. Reich ; D. Pietschner ; G. Weidenspointner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; I. Schlichting ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; H. N. Chapman ; J. Hajdu
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-02-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Electrons ; Hot Temperature ; Lasers ; Mimiviridae/*chemistry ; Photons ; Time Factors ; X-Ray Diffraction/*instrumentation/*methods ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Spence, J. C. H.
    International Union of Crystallography (IUCr)
    Published 2018
    Staff View
    Publication Date:
    2018-04-20
    Publisher:
    International Union of Crystallography (IUCr)
    Electronic ISSN:
    2052-2525
    Topics:
    Geosciences
    Physics
    Keywords:
    X-ray lasersXFELsprotein dynamicsstructural biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  12. 12
    Scheinfein, M. R. ; Qian, W. ; Spence, J. C. H.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The electron optical properties of nanometer sized field-emission cathodes are examined for suitability as electron sources for low-voltage scanning electron microscopy, low-voltage transmission point projection microscopy, and low-voltage transmission and reflection electron holography. First-order electron optical properties, aperture and chromatic aberrations, and source coherence are computed using an all-orders numerical method, and compared with analytically computed properties where possible. The electron optical properties of planar emitters, conventional field-emission tips, and new nanotip structures are compared in the absence of space-charge effects. It is found that the spherical and chromatic aberrations of nanotips are dominated by their base structures and that beams produced by nanotips can be considered as totally coherent.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Qian, W. ; Scheinfein, M. R. ; Spence, J. C. H.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The brightness of nanometer-sized field-emission-electron sources have been measured experimentally. Ultrasharp tungsten (111) single-crystal tips were fabricated in situ using Ne sputtering and field evaporation, and monitored using field ion microscopy. The average brightness of single-atom-terminated nanotips was found to be 3.3×108 A cm−2 sr−1 at 470 V, or 7.7×1010 A cm−2 sr−1 when extrapolated to 100 kV. These results show an improvement of about two orders of magnitude in source brightness over existing cold field-emission-electron sources, and produce a beam with greater particle flux per unit energy than those obtainable using current synchrotron/wiggler/undulator devices.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Graham, R. J. ; Spence, J. C. H. ; Roedel, R. J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1986
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Zn-doped GaAs diffused with Sn has been examined in cross section by transmission electron microscopy (TEM) and high-resolution cathodoluminescence (CL) in an attempt to account for the penetration of Sn into this material but the apparent lack of any electricity activity. TEM shows that small Sn-rich precipitates are present in the GaAs near the surface. CL indicates that some of the Sn dopes of GaAs n-type, but additionally that new emissions in the spectra at ∼1.44 and ∼1.455 eV are seen to originate from the diffused region. A possible explanation for the lack of electrical activity of the Sn is discussed in terms of these results and may lie in the formation of a compensating Sn-related complex or an accumulation of Zn in the diffused region.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Kim, Y. ; Spence, J. C. H. ; Long, N. ; Bergholz, W. ; O'Keeffe, M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1987
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Coherent electron microdiffraction patterns have been obtained from a new crystalline precipitate found in silicon wafers annealed at 635 °C for 256 h. On the basis of the experimental evidence presented, the most likely structure is that of keatite (SiO2, tetragonal). The implications for the study of oxygen precipitation in silicon are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Spence, J. C. H. ; Zuo, J. M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1988
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    A parallel detection system for electrons in the 10–800-kV energy range is described. The design is based on a 576×382 pixel charge-coupled device array operating at liquid-nitrogen temperature. This is coupled by fiber optics to a single-crystal YAG screen, which serves as the primary detection element. The performance of the system for quantitative electron diffraction and imaging studies is described. The system will record a maximum count of 16 000 per pixel with low noise at a frame rate of 2.5 frames per second.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Spence, J. C. H. ; Cowley, J. M. ; Zuo, J. M.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Qian, W. ; Scheinfein, M. R. ; Spence, J. C. H.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Electron optical properties of nanometer diameter field emission electron sources have been calculated using ray tracing methods. The spherical and chromatic aberration coefficients referred to the object plane were found to be on the order of angstroms. The effective source size was estimated to be much smaller than that in a conventional field emission source. The ultimate resolution of a lensless point projection electron microscope, which depends on both the source aberrations and the effective source size, were also in the order of angstroms. The beam angular half-width on the anode was 7.4° relative to the virtual image position on the optic axis, and the corresponding coherence width was 9.6°, suggesting that the source is totally coherent.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    1438-1168
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Geosciences
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Ourmazd, A. ; Spence, J. C. H.

    [s.l.] : Nature Publishing Group
    Published 1987
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] We study the lattice imaging of YBa2Cu3O7 at 400 kV and discuss the oxygen arrangement in the basal plane. Similar arguments apply to the oxygen vacancy at the Y plane and to imaging at lower accelerating voltages. We assume that no systematic changes occur in the metal-frame stoichiometry with ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses