Search Results - (Author, Cooperation:J. A. Doudna)

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  1. 1
    E. Kaya ; J. A. Doudna
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-05-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Argonaute Proteins/*chemistry ; Humans
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    S. C. Knight ; L. Xie ; W. Deng ; B. Guglielmi ; L. B. Witkowsky ; L. Bosanac ; E. T. Zhang ; M. El Beheiry ; J. B. Masson ; M. Dahan ; Z. Liu ; J. A. Doudna ; R. Tjian
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-11-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    3T3 Cells ; Animals ; Bacterial Proteins/chemistry/*metabolism ; *CRISPR-Cas Systems ; Chromatin/chemistry/*metabolism/ultrastructure ; Clustered Regularly Interspaced Short Palindromic Repeats ; *DNA Cleavage ; Endonucleases/chemistry/*metabolism ; *Genetic Engineering ; Genome ; Mice ; Single-Cell Analysis
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    F. Jiang ; D. W. Taylor ; J. S. Chen ; J. E. Kornfeld ; K. Zhou ; A. J. Thompson ; E. Nogales ; J. A. Doudna
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-02-04
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *CRISPR-Cas Systems ; Catalytic Domain ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Crystallography, X-Ray ; DNA/*chemistry ; *DNA Cleavage ; Endonucleases/*chemistry/ultrastructure ; Genetic Engineering ; Genome ; Nucleic Acid Conformation ; Protein Conformation ; RNA/chemistry ; RNA, Guide ; Streptococcus pyogenes/*enzymology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    M. Jinek ; K. Chylinski ; I. Fonfara ; M. Hauer ; J. A. Doudna ; E. Charpentier
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-06-30
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacteriophages/*immunology ; Base Sequence ; *DNA Breaks, Double-Stranded ; *DNA Cleavage ; Deoxyribonucleases, Type II Site-Specific/chemistry/genetics/*metabolism ; *Inverted Repeat Sequences ; Molecular Sequence Data ; Nucleic Acid Conformation ; Plasmids/metabolism ; RNA/chemistry/*metabolism ; Streptococcus pyogenes/*enzymology/physiology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    J. A. Doudna ; E. Charpentier
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-11-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Caspase 9 ; *Clustered Regularly Interspaced Short Palindromic Repeats ; DNA Cleavage ; Gene Targeting ; Genetic Engineering/*methods ; Genome, Human/*genetics ; Humans ; RNA, Guide
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    D. W. Taylor ; Y. Zhu ; R. H. Staals ; J. E. Kornfeld ; A. Shinkai ; J. van der Oost ; E. Nogales ; J. A. Doudna
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-04-04
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Clustered Regularly Interspaced Short Palindromic Repeats ; Cryoelectron Microscopy ; Multiprotein Complexes/*chemistry/ultrastructure ; RNA/*chemistry/ultrastructure ; *RNA Cleavage ; Thermus thermophilus/*immunology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    M. Jinek ; F. Jiang ; D. W. Taylor ; S. H. Sternberg ; E. Kaya ; E. Ma ; C. Anders ; M. Hauer ; K. Zhou ; S. Lin ; M. Kaplan ; A. T. Iavarone ; E. Charpentier ; E. Nogales ; J. A. Doudna
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-02-08
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Actinomyces/*enzymology ; Amino Acid Sequence ; Bacterial Proteins/*chemistry ; Caspase 9/*chemistry ; Crystallography, X-Ray ; DNA Cleavage ; Molecular Sequence Data ; Nucleic Acid Conformation ; Protein Structure, Secondary ; Protein Structure, Tertiary ; RNA/*chemistry ; Streptococcus pyogenes/*enzymology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    F. Jiang ; K. Zhou ; L. Ma ; S. Gressel ; J. A. Doudna
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-06-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Argonaute Proteins/*chemistry ; Base Sequence ; *CRISPR-Cas Systems ; Caspase 9/*chemistry/genetics ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Crystallography, X-Ray ; DNA/chemistry ; *DNA Cleavage ; Enzyme Activation ; Evolution, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation ; Protein Structure, Tertiary ; RNA Interference ; RNA, Guide/*chemistry ; Streptococcus pyogenes/*enzymology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2015-03-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Biotechnology/ethics ; *Caspase 9 ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Gene Transfer, Horizontal ; Genetic Engineering/*ethics ; Genetic Predisposition to Disease/*prevention & control ; Genome, Human/genetics ; Genomics ; *Germ Cells ; Humans ; Risk Management ; Targeted Gene Repair/*ethics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    M. R. O'Connell ; B. L. Oakes ; S. H. Sternberg ; A. East-Seletsky ; M. Kaplan ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-10-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Base Sequence ; CRISPR-Associated Proteins/*metabolism ; CRISPR-Cas Systems/*physiology ; Cell Extracts ; Clustered Regularly Interspaced Short Palindromic Repeats/*genetics ; DNA/chemistry/genetics/metabolism ; Genetic Engineering/*methods ; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/genetics ; HeLa Cells ; Humans ; Nucleotide Motifs ; Oligonucleotides/chemistry/genetics/metabolism ; RNA/chemistry/genetics/*metabolism ; RNA, Guide/chemistry/genetics/metabolism ; RNA, Messenger/genetics/isolation & purification/metabolism ; Substrate Specificity
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  11. 11
    S. H. Sternberg ; B. LaFrance ; M. Kaplan ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-11-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Allosteric Regulation ; Bacterial Proteins/chemistry/metabolism ; Base Pairing ; Binding Sites ; CRISPR-Associated Proteins/*chemistry/*metabolism ; *CRISPR-Cas Systems ; Catalytic Domain ; DNA/chemistry/*metabolism ; DNA Breaks, Double-Stranded ; *DNA Cleavage ; Endonucleases/chemistry/*metabolism ; Fluorescence Resonance Energy Transfer ; *Genetic Engineering ; Models, Molecular ; RNA, Guide/chemistry/metabolism ; Streptococcus pyogenes
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  12. 12
    S. H. Sternberg ; S. Redding ; M. Jinek ; E. C. Greene ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-01-31
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Apoenzymes/metabolism ; *Base Pairing ; Base Sequence ; Biocatalysis ; CRISPR-Associated Proteins/*metabolism ; *CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats/*genetics ; DNA/chemistry/genetics/metabolism ; *DNA Cleavage ; Diffusion ; Endonucleases/*metabolism ; Enzyme Activation ; Genetic Engineering/methods ; Genome/genetics ; Nucleic Acid Denaturation ; Nucleic Acid Heteroduplexes/chemistry/genetics/metabolism ; Nucleotide Motifs ; RNA/chemistry/*genetics/metabolism ; Streptococcus pyogenes/enzymology/immunology ; Substrate Specificity ; Thermodynamics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  13. 13
    S. F. Ataide ; N. Schmitz ; K. Shen ; A. Ke ; S. O. Shan ; J. A. Doudna ; N. Ban
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-02-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacterial Proteins/*chemistry/metabolism ; Base Sequence ; Binding Sites ; Crystallization ; Crystallography, X-Ray ; Enzyme Activation ; Escherichia coli/chemistry/metabolism ; Escherichia coli Proteins/*chemistry/metabolism ; GTP Phosphohydrolases/chemistry/metabolism ; Guanosine Triphosphate/analogs & derivatives/chemistry/metabolism ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Models, Biological ; Models, Molecular ; Nucleic Acid Conformation ; Protein Conformation ; Protein Multimerization ; Protein Structure, Tertiary ; Protein Transport ; RNA, Bacterial/*chemistry/metabolism ; Receptors, Cytoplasmic and Nuclear/*chemistry/metabolism ; Ribosomal Proteins/chemistry/metabolism ; Ribosomes/metabolism ; Signal Recognition Particle/*chemistry/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  14. 14
    J. K. Nunez ; L. B. Harrington ; P. J. Kranzusch ; A. N. Engelman ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Adaptive Immunity ; Bacteriophage M13/genetics/immunology ; Base Sequence ; CRISPR-Associated Proteins/chemistry/*metabolism ; Catalytic Domain ; Clustered Regularly Interspaced Short Palindromic Repeats/*genetics ; Crystallography, X-Ray ; DNA, Viral/chemistry/*genetics/*immunology/metabolism ; Escherichia coli/enzymology/genetics/immunology/virology ; Integrases/chemistry/metabolism ; Models, Molecular ; *Virus Integration/genetics/immunology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  15. 15
    J. K. Nunez ; A. S. Lee ; A. Engelman ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-02-25
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    AT Rich Sequence/genetics ; *Adaptive Immunity ; CRISPR-Associated Proteins/immunology/*metabolism ; CRISPR-Cas Systems/immunology ; Clustered Regularly Interspaced Short Palindromic Repeats/*genetics ; DNA/chemistry/genetics/*metabolism ; DNA, Superhelical/chemistry/genetics/metabolism ; Escherichia coli/*enzymology/genetics/*immunology/virology ; Integrases/*metabolism ; Nucleic Acid Conformation ; Substrate Specificity ; Transposases/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  16. 16
    B. Wiedenheft ; G. C. Lander ; K. Zhou ; M. M. Jore ; S. J. Brouns ; J. van der Oost ; J. A. Doudna ; E. Nogales
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-09-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Base Pairing ; Cryoelectron Microscopy ; Escherichia coli K12/chemistry/*genetics/*immunology/virology ; Escherichia coli Proteins/chemistry/immunology/*ultrastructure ; Inverted Repeat Sequences/genetics/immunology ; Macromolecular Substances/*chemistry/metabolism/*ultrastructure ; Models, Biological ; Models, Molecular ; Protein Conformation ; RNA, Bacterial/genetics/*immunology/*ultrastructure
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  17. 17
    B. Wiedenheft ; S. H. Sternberg ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-02-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Archaea/*genetics ; Bacteria/*genetics ; *Gene Expression Regulation, Bacterial ; *Gene Silencing ; Models, Molecular ; RNA Interference ; RNA, Archaeal/biosynthesis/chemistry/genetics/*metabolism ; RNA, Bacterial/biosynthesis/chemistry/genetics/*metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  18. 18
    E. Charpentier ; J. A. Doudna
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-03-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacteria/enzymology ; Biotechnology/methods ; DNA/genetics/metabolism ; DNA Cleavage ; Endonucleases/metabolism ; Genetic Engineering/*methods ; Humans ; Inverted Repeat Sequences/*genetics ; RNA, Bacterial/genetics ; RNA, Guide/*genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  19. 19
    Chen, J. S., Ma, E., Harrington, L. B., Da Costa, M., Tian, X., Palefsky, J. M., Doudna, J. A.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-04-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Biochemistry, Molecular Biology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  20. 20
    Knott, G. J., Doudna, J. A.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-08-31
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Medicine, Diseases, Molecular Biology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press