Search Results - (Author, Cooperation:I. Girault)
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1Latest Papers from Table of Contents or Articles in PressL. Boussemart ; H. Malka-Mahieu ; I. Girault ; D. Allard ; O. Hemmingsson ; G. Tomasic ; M. Thomas ; C. Basmadjian ; N. Ribeiro ; F. Thuaud ; C. Mateus ; E. Routier ; N. Kamsu-Kom ; S. Agoussi ; A. M. Eggermont ; L. Desaubry ; C. Robert ; S. Vagner
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antineoplastic Agents/pharmacology ; Cell Death/drug effects ; Cell Line, Tumor ; Colonic Neoplasms/pathology ; *Drug Resistance, Neoplasm/drug effects ; Drug Synergism ; Eukaryotic Initiation Factor-4A/antagonists & inhibitors/metabolism ; Eukaryotic Initiation Factor-4E/metabolism ; Eukaryotic Initiation Factor-4F/*antagonists & inhibitors/chemistry/*metabolism ; Eukaryotic Initiation Factor-4G/metabolism ; Female ; Humans ; Indoles/pharmacology ; MAP Kinase Signaling System/drug effects ; Melanoma/*drug therapy/genetics/pathology ; Mice ; Mitogen-Activated Protein Kinase Kinases/*antagonists & inhibitors ; Phosphorylation/drug effects ; Protein Binding/drug effects ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins B-raf/*antagonists & inhibitors/genetics ; Signal Transduction/drug effects ; Sulfonamides/pharmacology ; Thyroid Neoplasms/pathology ; Triterpenes/pharmacology ; Xenograft Model Antitumor AssaysPublished by: -
2Articles: DFG German National LicensesCadet, J. ; Girault, I. ; Gromova, M. ; Molko, D. ; Odin, F. ; Polverelli, M.
Springer
Published 1995Staff ViewISSN: 1432-2099Source: Springer Online Journal Archives 1860-2000Topics: BiologyPhysicsNotes: Abstract In this short survey the main, available information on the molecular mechanisms of action of heavy ions on DNA is critically reviewed. Formation of single-and double-stranded DNA breaks in cells exposed to heavy particles is well established. On the other hand, base damage and, in a more general way, clustered lesions, whose formation should be increased upon exposure to heavy ions, have not yet been isolated and characterized. Efforts should be made to identify this important class of DNA damage in both isolated and cellular DNA. Sensitive and specific assays involving chemical and biochemical approaches have to be developed for such a purpose.Type of Medium: Electronic ResourceURL: