Search Results - (Author, Cooperation:G. W. Han)

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  1. 1
    Staff View
    Publication Date:
    2014-03-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Binding Sites ; Crystallography, X-Ray ; Disulfides/metabolism ; Fibrinolytic Agents/*chemistry ; Humans ; Ligands ; Models, Molecular ; Molecular Docking Simulation ; Niacin/*analogs & derivatives/chemistry/metabolism ; Protein Conformation ; Purinergic P2Y Receptor Antagonists/chemistry/metabolism ; Receptors, Purinergic P2Y12/*chemistry/metabolism ; Sulfonamides/*chemistry/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-03-31
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine Diphosphate/analogs & derivatives/chemistry/metabolism ; Binding Sites ; Crystallography, X-Ray ; Deoxyadenine Nucleotides/*chemistry/*metabolism/pharmacology ; Humans ; Ligands ; Models, Molecular ; Molecular Conformation ; Purinergic P2Y Receptor Antagonists/*chemistry/metabolism/pharmacology ; Receptors, Purinergic P2Y1/*chemistry/*metabolism ; Thionucleotides/chemistry/metabolism ; Uracil/*analogs & derivatives/chemistry/metabolism/pharmacology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    F. Xu ; H. Wu ; V. Katritch ; G. W. Han ; K. A. Jacobson ; Z. G. Gao ; V. Cherezov ; R. C. Stevens
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-03-12
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine/*analogs & derivatives/chemistry/metabolism ; Adenosine A2 Receptor Agonists/chemistry/*metabolism ; Binding Sites ; Crystallography, X-Ray ; Humans ; Hydrogen Bonding ; Ligands ; Models, Molecular ; Opsins/chemistry/metabolism ; Protein Conformation ; Protein Structure, Secondary ; Receptor, Adenosine A2A/*chemistry/*metabolism ; Rhodopsin/chemistry/metabolism ; Triazines/chemistry/metabolism ; Triazoles/chemistry/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    M. A. Hanson ; C. B. Roth ; E. Jo ; M. T. Griffith ; F. L. Scott ; G. Reinhart ; H. Desale ; B. Clemons ; S. M. Cahalan ; S. C. Schuerer ; M. G. Sanna ; G. W. Han ; P. Kuhn ; H. Rosen ; R. C. Stevens
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-02-22
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Anilides/chemistry ; Binding Sites ; Crystallography, X-Ray ; Models, Molecular ; Muramidase/chemistry ; Mutagenesis ; Organophosphonates/chemistry ; Protein Conformation ; Receptors, Lysosphingolipid/agonists/antagonists & inhibitors/*chemistry/genetics ; Recombinant Fusion Proteins/chemistry/genetics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Y. Kang ; X. E. Zhou ; X. Gao ; Y. He ; W. Liu ; A. Ishchenko ; A. Barty ; T. A. White ; O. Yefanov ; G. W. Han ; Q. Xu ; P. W. de Waal ; J. Ke ; M. H. Tan ; C. Zhang ; A. Moeller ; G. M. West ; B. D. Pascal ; N. Van Eps ; L. N. Caro ; S. A. Vishnivetskiy ; R. J. Lee ; K. M. Suino-Powell ; X. Gu ; K. Pal ; J. Ma ; X. Zhi ; S. Boutet ; G. J. Williams ; M. Messerschmidt ; C. Gati ; N. A. Zatsepin ; D. Wang ; D. James ; S. Basu ; S. Roy-Chowdhury ; C. E. Conrad ; J. Coe ; H. Liu ; S. Lisova ; C. Kupitz ; I. Grotjohann ; R. Fromme ; Y. Jiang ; M. Tan ; H. Yang ; J. Li ; M. Wang ; Z. Zheng ; D. Li ; N. Howe ; Y. Zhao ; J. Standfuss ; K. Diederichs ; Y. Dong ; C. S. Potter ; B. Carragher ; M. Caffrey ; H. Jiang ; H. N. Chapman ; J. C. Spence ; P. Fromme ; U. Weierstall ; O. P. Ernst ; V. Katritch ; V. V. Gurevich ; P. R. Griffin ; W. L. Hubbell ; R. C. Stevens ; V. Cherezov ; K. Melcher ; H. E. Xu
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Arrestin/*chemistry/*metabolism ; Binding Sites ; Crystallography, X-Ray ; Disulfides/chemistry/metabolism ; Humans ; Lasers ; Mice ; Models, Molecular ; Multiprotein Complexes/biosynthesis/chemistry/metabolism ; Protein Binding ; Reproducibility of Results ; Rhodopsin/*chemistry/*metabolism ; Signal Transduction ; X-Rays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2014-05-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine Diphosphate/*analogs & derivatives/chemistry/metabolism ; Adenosine Triphosphate/*analogs & derivatives/chemistry/metabolism ; Binding Sites ; Crystallography, X-Ray ; Humans ; Ligands ; Models, Molecular ; Niacin/analogs & derivatives/chemistry/metabolism ; Protein Conformation ; Purinergic P2Y Receptor Agonists/*chemistry/metabolism ; Purinergic P2Y Receptor Antagonists/chemistry/metabolism ; Receptors, Purinergic P2Y12/*chemistry/metabolism ; Substrate Specificity ; Sulfonamides/chemistry/metabolism ; Thionucleotides/*chemistry/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    C. Wang ; Y. Jiang ; J. Ma ; H. Wu ; D. Wacker ; V. Katritch ; G. W. Han ; W. Liu ; X. P. Huang ; E. Vardy ; J. D. McCorvy ; X. Gao ; X. E. Zhou ; K. Melcher ; C. Zhang ; F. Bai ; H. Yang ; L. Yang ; H. Jiang ; B. L. Roth ; V. Cherezov ; R. C. Stevens ; H. E. Xu
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-03-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Binding Sites ; Crystallography, X-Ray ; Dihydroergotamine/chemistry/*metabolism ; Ergotamine/chemistry/*metabolism ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Lysergic Acid Diethylamide/chemistry/metabolism ; Models, Molecular ; Molecular Docking Simulation ; Molecular Sequence Data ; Mutagenesis ; Norfenfluramine/chemistry/metabolism ; Pindolol/analogs & derivatives/chemistry/metabolism ; Propranolol/chemistry/metabolism ; Protein Conformation ; Protein Folding ; Protein Structure, Secondary ; Receptor, Serotonin, 5-HT1B/*chemistry/genetics/*metabolism ; Serotonin 5-HT1 Receptor Agonists/*chemistry/*metabolism ; Tryptamines/chemistry/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2013-12-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Crystallography, X-Ray/*instrumentation/*methods ; Humans ; Lasers ; Protein Conformation ; Receptor, Serotonin, 5-HT2B/chemistry/radiation effects ; Receptors, G-Protein-Coupled/*chemistry/radiation effects ; Time Factors
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    D. Wacker ; C. Wang ; V. Katritch ; G. W. Han ; X. P. Huang ; E. Vardy ; J. D. McCorvy ; Y. Jiang ; M. Chu ; F. Y. Siu ; W. Liu ; H. E. Xu ; V. Cherezov ; B. L. Roth ; R. C. Stevens
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-03-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Motifs ; Amino Acid Sequence ; Arrestin/metabolism ; Arrestins/metabolism ; Binding Sites ; Crystallography, X-Ray ; Ergolines/chemistry/metabolism ; Ergotamine/chemistry/*metabolism ; HEK293 Cells ; Humans ; Ligands ; Lysergic Acid Diethylamide/chemistry/metabolism ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Protein Structure, Secondary ; Receptor, Serotonin, 5-HT1B/chemistry/*metabolism ; Receptor, Serotonin, 5-HT2B/*chemistry/*metabolism ; Receptors, Serotonin/chemistry/metabolism ; Signal Transduction
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Q. Tan ; Y. Zhu ; J. Li ; Z. Chen ; G. W. Han ; I. Kufareva ; T. Li ; L. Ma ; G. Fenalti ; W. Zhang ; X. Xie ; H. Yang ; H. Jiang ; V. Cherezov ; H. Liu ; R. C. Stevens ; Q. Zhao ; B. Wu
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-09-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Binding Sites ; Cyclohexanes/*chemistry/pharmacology ; HIV Envelope Protein gp120/metabolism ; HIV Fusion Inhibitors/*chemistry/pharmacology ; HIV-1/*drug effects/physiology ; Humans ; Ligands ; Protein Conformation ; Receptors, CCR5/*chemistry/metabolism ; Receptors, CXCR4/chemistry ; Triazoles/*chemistry/pharmacology ; Virus Internalization/*drug effects
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  11. 11
    H. Wu ; C. Wang ; K. J. Gregory ; G. W. Han ; H. P. Cho ; Y. Xia ; C. M. Niswender ; V. Katritch ; J. Meiler ; V. Cherezov ; P. J. Conn ; R. C. Stevens
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-03-08
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Allosteric Regulation ; Allosteric Site ; Amino Acid Sequence ; Benzamides/*chemistry/*metabolism ; Binding Sites ; Cholesterol ; Crystallography, X-Ray ; Humans ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Protein Conformation ; Protein Multimerization ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Receptors, Metabotropic Glutamate/*chemistry/*metabolism ; Structure-Activity Relationship ; Thiazoles/*chemistry/*metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  12. 12
    A. D. Pearson ; J. H. Mills ; Y. Song ; F. Nasertorabi ; G. W. Han ; D. Baker ; R. C. Stevens ; P. G. Schultz
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-02-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alanine/*analogs & derivatives/chemistry ; Archaeal Proteins/*chemistry ; Biphenyl Compounds/*chemistry ; Computer Simulation ; Computer-Aided Design ; Crystallography, X-Ray ; Entropy ; Models, Chemical ; Protein Structure, Secondary ; Pyrococcus abyssi/*enzymology ; Software ; Threonine-tRNA Ligase/*chemistry
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  13. 13
    L. Qin ; I. Kufareva ; L. G. Holden ; C. Wang ; Y. Zheng ; C. Zhao ; G. Fenalti ; H. Wu ; G. W. Han ; V. Cherezov ; R. Abagyan ; R. C. Stevens ; T. M. Handel
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-01-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Chemokine CXCL12/chemistry ; Chemokines/*chemistry ; Crystallography, X-Ray ; Drug Design ; Humans ; Models, Chemical ; Molecular Sequence Data ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Receptors, CXCR4/agonists/antagonists & inhibitors/*chemistry ; Structural Homology, Protein
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  14. 14
    W. Liu ; E. Chun ; A. A. Thompson ; P. Chubukov ; F. Xu ; V. Katritch ; G. W. Han ; C. B. Roth ; L. H. Heitman ; I. J. AP ; V. Cherezov ; R. C. Stevens
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-07-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenosine A2 Receptor Agonists/metabolism ; Adenosine A2 Receptor Antagonists/metabolism ; Allosteric Regulation ; Cholesterol/chemistry ; Crystallography, X-Ray ; Cytochrome b Group/chemistry ; Escherichia coli Proteins/chemistry ; HEK293 Cells ; Humans ; Hydrogen Bonding ; Ligands ; Lipid Bilayers ; Lipids/chemistry ; Models, Molecular ; Protein Conformation ; Protein Engineering ; Protein Structure, Secondary ; Receptor, Adenosine A2A/*chemistry/*metabolism ; Recombinant Fusion Proteins/chemistry/metabolism ; Sodium/*analysis ; Triazines/metabolism ; Triazoles/metabolism ; Water/chemistry
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  15. 15
    Staff View
    Publication Date:
    2011-06-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Binding Sites ; Crystallography, X-Ray ; Doxepin/chemistry/*metabolism ; Histamine Antagonists/chemistry/*metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Isomerism ; Ligands ; Models, Molecular ; Phosphates/chemistry/metabolism ; Protein Binding ; Protein Conformation ; Receptors, Adrenergic, beta-2/chemistry ; Receptors, Dopamine D3/chemistry ; Receptors, Histamine H1/*chemistry/*metabolism ; Substrate Specificity
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  16. 16
    Staff View
    Publication Date:
    2012-03-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Binding Sites ; Crystallography, X-Ray ; Diterpenes, Clerodane/chemistry/metabolism/pharmacology ; Guanidines/chemistry ; Humans ; Models, Molecular ; Morphinans/chemistry ; Mutagenesis, Site-Directed ; Naltrexone/analogs & derivatives/chemistry/metabolism ; Piperidines/*chemistry/pharmacology ; Protein Conformation ; Receptors, Adrenergic, beta-2/chemistry ; Receptors, CXCR4/chemistry/metabolism ; Receptors, Opioid, kappa/*antagonists & inhibitors/*chemistry/genetics/metabolism ; Structure-Activity Relationship ; Tetrahydroisoquinolines/*chemistry/pharmacology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  17. 17
    Staff View
    Publication Date:
    2013-07-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Binding Sites ; Cell Membrane/metabolism ; Crystallography, X-Ray ; Glucagon/chemistry/metabolism ; Humans ; Ligands ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Protein Binding ; Protein Structure, Tertiary ; Receptors, CXCR4/chemistry/classification ; Receptors, Glucagon/*chemistry/*classification/genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  18. 18
    C. Wang ; H. Wu ; V. Katritch ; G. W. Han ; X. P. Huang ; W. Liu ; F. Y. Siu ; B. L. Roth ; V. Cherezov ; R. C. Stevens
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-05-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Motifs ; Amino Acid Sequence ; Antineoplastic Agents/*chemistry/metabolism ; Binding Sites ; Crystallography, X-Ray ; Disulfides/chemistry ; Frizzled Receptors/chemistry/classification ; Humans ; Ligands ; Models, Molecular ; Molecular Sequence Data ; Phthalazines/*chemistry/metabolism ; Protein Structure, Tertiary ; Receptors, G-Protein-Coupled/*chemistry/classification/metabolism ; Structural Homology, Protein
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press