Search Results - (Author, Cooperation:G. Iyer)
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1K. G. Paulson; V. Voillet; M. S. McAfee; D. S. Hunter; F. D. Wagener; M. Perdicchio; W. J. Valente; S. J. Koelle; C. D. Church; N. Vandeven; H. Thomas; A. G. Colunga; J. G. Iyer; C. Yee; R. Kulikauskas; D. M. Koelle; R. H. Pierce; J. H. Bielas; P. D. Greenberg; S. Bhatia; R. Gottardo; P. Nghiem; A. G. Chapuis
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-09-25Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
2G. Iyer ; A. J. Hanrahan ; M. I. Milowsky ; H. Al-Ahmadie ; S. N. Scott ; M. Janakiraman ; M. Pirun ; C. Sander ; N. D. Socci ; I. Ostrovnaya ; A. Viale ; A. Heguy ; L. Peng ; T. A. Chan ; B. Bochner ; D. F. Bajorin ; M. F. Berger ; B. S. Taylor ; D. B. Solit
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-08-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antineoplastic Agents/*therapeutic use ; Clinical Trials, Phase II as Topic ; Codon, Nonsense ; Disease-Free Survival ; Drug Resistance, Neoplasm/*genetics ; Everolimus ; Genome, Human ; Genome-Wide Association Study ; Humans ; Molecular Targeted Therapy ; Multiprotein Complexes ; Neoplasm Metastasis ; Neurofibromin 2/genetics ; Proteins/antagonists & inhibitors ; Sequence Deletion ; Sirolimus/*analogs & derivatives/therapeutic use ; TOR Serine-Threonine Kinases ; Tumor Suppressor Proteins/*genetics ; Urinary Bladder Neoplasms/*drug therapy/genetics/pathologyPublished by: -
3D. Juric ; P. Castel ; M. Griffith ; O. L. Griffith ; H. H. Won ; H. Ellis ; S. H. Ebbesen ; B. J. Ainscough ; A. Ramu ; G. Iyer ; R. H. Shah ; T. Huynh ; M. Mino-Kenudson ; D. Sgroi ; S. Isakoff ; A. Thabet ; L. Elamine ; D. B. Solit ; S. W. Lowe ; C. Quadt ; M. Peters ; A. Derti ; R. Schegel ; A. Huang ; E. R. Mardis ; M. F. Berger ; J. Baselga ; M. Scaltriti
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-11-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Breast Neoplasms/*drug therapy/*genetics/metabolism/pathology ; Drug Resistance, Neoplasm/drug effects/*genetics ; Female ; Humans ; Loss of Heterozygosity/drug effects/genetics ; Mice ; Mice, Nude ; PTEN Phosphohydrolase/*deficiency/*genetics/metabolism ; Phosphatidylinositol 3-Kinases/*antagonists & inhibitors ; Thiazoles/*pharmacology/therapeutic use ; Xenograft Model Antitumor AssaysPublished by: -
4Chang, M. T., Penson, A., Desai, N. B., Socci, N. D., Shen, R., Seshan, V. E., Kundra, R., Abeshouse, A., Viale, A., Cha, E. K., Hao, X., Reuter, V. E., Rudin, C. M., Bochner, B. H., Rosenberg, J. E., Bajorin, D. F., Schultz, N., Berger, M. F., Iyer, G., Solit, D. B., Al-Ahmadie, H. A., Taylor, B. S.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-04-14Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
5Dumouchel, J. L., Chemuturi, N., Milton, M. N., Camenisch, G., Chastain, J., Walles, M., Sasseville, V., Gunduz, M., Iyer, G. R., Argikar, U. A.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-10-18Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0090-9556Electronic ISSN: 1521-009XTopics: Chemistry and PharmacologyMedicinePublished by: -
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ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
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ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] FOLLOWING a number of observations which r indicated an increased rate of oxygen consumption by leucocytes during phagocytosis, Karnovsky and his colleagues1"3 have shown that in the process of engulfment of particles by polymorphonuclear leucocytes, obtained from peritoneal exudates of guinea ...Type of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Erythrocytes from normal subjects and from cases of iron deficiency anemia were exposed to hydrogen peroxide and the extent of membrane lipid peroxidation studied. Significantly less peroxidation was observed in intact anemic erythrocytes compared to normal. However, when isolated membrane lipids were subjected to peroxidation, there was no significant difference between the two groups. It is unlikely that lipid peroxidation per se plays a major role in the reported decrease in red cell life-span in iron deficiency. *** DIRECT SUPPORT *** A2025146 00003Type of Medium: Electronic ResourceURL: -
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ISSN: 0942-0940Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Electroencephalographic studies in 100 cases of intracranial space occupying lesions are reported and the value of EEG is compared with other investigative procedures. With cerebral hemisphere lesions good localisation was possible in 82.5% and lateralisation alone was possible in a further 13.9%. In 66% of the cases of third ventricle and posterior fossa tumours the EEGs were abnormal but definite localisation was not possible. With posterior fossa, third ventricle and sellar or suprasellar tumours, and with subdural haematomas, neuroradiological contrast studies gave better localisation than did EEGs. With meningiomas the brain scan proved to be a more reliable investigative procedure than electroencephalography. With astrocytomas Grs. III and IV, even though EEG was always abnormal, good localisation was possible in only 77.8%. However, with low grade gliomas EEG gave positive results more often than did the brain scan. An EEG pattern suggestive of an acutely destructive lesion was noted in 94.5% of the cases of astrocytoma Grs. III and IV, in 100% of the cases of cerebral abscess, and in 66% of the cases of cerebral metastasis. An EEG pattern suggestive of a slow growing lesion was noted in 83.3% of the granulomas, 77% of the less malignant gliomas, and 71.5% of the meningiomas.Type of Medium: Electronic ResourceURL: -
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ISSN: 0021-9541Keywords: Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyMedicineNotes: Galactose metabolism in the red cells shows marked interspecies and even intraspecies variations. Red cells of guinea pig, dog and a group of rabbits metabolize galactose to a higher extent than those of other species, including human. In the rabbit, the difference in red cell galactokinase activity could not be correlated to the overall utilization of this sugar in the body.Additional Material: 2 Ill.Type of Medium: Electronic ResourceURL: