Search Results - (Author, Cooperation:G. Hauser)
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1W. Treberspurg, R. Andritschke, G. Hauser, P. Lechner, N. Meidinger, J. Ninkovic, J. Müller-Seidlitz and F. Schopper
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-09-18Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
2H. N. Chapman ; P. Fromme ; A. Barty ; T. A. White ; R. A. Kirian ; A. Aquila ; M. S. Hunter ; J. Schulz ; D. P. DePonte ; U. Weierstall ; R. B. Doak ; F. R. Maia ; A. V. Martin ; I. Schlichting ; L. Lomb ; N. Coppola ; R. L. Shoeman ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; P. Holl ; M. Liang ; M. Barthelmess ; C. Caleman ; S. Boutet ; M. J. Bogan ; J. Krzywinski ; C. Bostedt ; S. Bajt ; L. Gumprecht ; B. Rudek ; B. Erk ; C. Schmidt ; A. Homke ; C. Reich ; D. Pietschner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; M. Messerschmidt ; J. D. Bozek ; S. P. Hau-Riege ; M. Frank ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; G. J. Williams ; J. Hajdu ; N. Timneanu ; M. M. Seibert ; J. Andreasson ; A. Rocker ; O. Jonsson ; M. Svenda ; S. Stern ; K. Nass ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; K. E. Schmidt ; X. Wang ; I. Grotjohann ; J. M. Holton ; T. R. Barends ; R. Neutze ; S. Marchesini ; R. Fromme ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; I. Andersson ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; J. C. Spence
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Crystallography, X-Ray/instrumentation/*methods ; Lasers ; Models, Molecular ; Nanoparticles/*chemistry ; Nanotechnology/instrumentation/*methods ; Photosystem I Protein Complex/*chemistry ; Protein Conformation ; Time Factors ; X-RaysPublished by: -
3M. M. Seibert ; T. Ekeberg ; F. R. Maia ; M. Svenda ; J. Andreasson ; O. Jonsson ; D. Odic ; B. Iwan ; A. Rocker ; D. Westphal ; M. Hantke ; D. P. DePonte ; A. Barty ; J. Schulz ; L. Gumprecht ; N. Coppola ; A. Aquila ; M. Liang ; T. A. White ; A. Martin ; C. Caleman ; S. Stern ; C. Abergel ; V. Seltzer ; J. M. Claverie ; C. Bostedt ; J. D. Bozek ; S. Boutet ; A. A. Miahnahri ; M. Messerschmidt ; J. Krzywinski ; G. Williams ; K. O. Hodgson ; M. J. Bogan ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; I. Andersson ; S. Bajt ; M. Barthelmess ; J. C. Spence ; P. Fromme ; U. Weierstall ; R. Kirian ; M. Hunter ; R. B. Doak ; S. Marchesini ; S. P. Hau-Riege ; M. Frank ; R. L. Shoeman ; L. Lomb ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; C. Schmidt ; L. Foucar ; N. Kimmel ; P. Holl ; B. Rudek ; B. Erk ; A. Homke ; C. Reich ; D. Pietschner ; G. Weidenspointner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; I. Schlichting ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; H. N. Chapman ; J. Hajdu
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Electrons ; Hot Temperature ; Lasers ; Mimiviridae/*chemistry ; Photons ; Time Factors ; X-Ray Diffraction/*instrumentation/*methods ; X-RaysPublished by: -
4N. D. Loh ; C. Y. Hampton ; A. V. Martin ; D. Starodub ; R. G. Sierra ; A. Barty ; A. Aquila ; J. Schulz ; L. Lomb ; J. Steinbrener ; R. L. Shoeman ; S. Kassemeyer ; C. Bostedt ; J. Bozek ; S. W. Epp ; B. Erk ; R. Hartmann ; D. Rolles ; A. Rudenko ; B. Rudek ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; G. Hauser ; P. Holl ; E. Pedersoli ; M. Liang ; M. S. Hunter ; L. Gumprecht ; N. Coppola ; C. Wunderer ; H. Graafsma ; F. R. Maia ; T. Ekeberg ; M. Hantke ; H. Fleckenstein ; H. Hirsemann ; K. Nass ; T. A. White ; H. J. Tobias ; G. R. Farquar ; W. H. Benner ; S. P. Hau-Riege ; C. Reich ; A. Hartmann ; H. Soltau ; S. Marchesini ; S. Bajt ; M. Barthelmess ; P. Bucksbaum ; K. O. Hodgson ; L. Struder ; J. Ullrich ; M. Frank ; I. Schlichting ; H. N. Chapman ; M. J. Bogan
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aerosols/*analysis/*chemistry ; Amino Acids/chemistry ; Electrons ; *Fractals ; Lasers ; *Mass Spectrometry ; *Motion ; Nanoparticles ; Particle Size ; Proteins/chemistry ; Solvents/chemistry ; Soot/*analysis/*chemistry ; Vibration ; X-Ray DiffractionPublished by: -
5Staff View
Type of Medium: articlePublication Date: 1980Keywords: Entwicklungsstörung ; Motorische Entwicklung ; Diagnostik ; Sachinformation ; VererbungIn: Erziehung & Unterricht, Bd. 130 (1980) H. 10, S. 139-143, 0014-0325Language: German -
6Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract— The lipid composition and metabolism of confluent cultures of cells derived from newborn hamster brain and having morphology characteristic of immature astrocytes or spongioblasts was investigated and compared to that of newborn hamster brain dispersions and cloned glioma cells (C6). The cells displayed stable morphology for at least 30 subcultures; thereafter spontaneous transformation occurred. No appreciable changes were observed in either composition or metabolic characteristics of any major neutral lipid or phospholipid class in successive subcultures or following transformation. The overall lipid composition of the hamster astrocyte cultures closely resembled that of newborn hamster brain, but the phospholipid composition showed substantial differences. The cells contained as a percent of lipid P relatively more ethanolamine plasmalogen, choline plasmalogen and sphingomyelin and somewhat less phosphatidylcholine and phosphatidylethanolamine. The phospholipids of the hamster astrocyte and C6 cells were similar. Of the lipid precursors examined, [U-14C]glucose was incorporated best into all preparations. C6 glioma cells incorporated both [U-14C]glucose and [1-14C]acetate most actively. From 69–88% of 32P incorporated into hamster astrocyte phospholipids was present in choline phosphoglycerides, whereas the corresonding figure for hamster brain dispersions was 53%. The ratio of specific activities of phosphatidylcholine to phosphatidylinositol was substantially higher in the cultured cells than in the brain preparations. The small pool of choline plasmalogen in the hamster astrocytes usually achieved the highest specific activity of any phospholipid. When [U-14C]glucose and [1-14C]acetate were precursors, the bulk of label in the astrocytes appeared in choline phosphoglycerides and triacyglycerol. Our results indicate that the hamster astrocyte cell line as grown expresses distinctive features of lipid composition and metabolism which are nearly constant through many generations.Type of Medium: Electronic ResourceURL: -
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ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Cultures of cloned neuroblastoma cells (N1E) in stationary phase and cloned glioma cells (C21) in confluency showed substantial differences in phospholipid composition. As a percentage of lipid P, N1E contained more phosphatidylcholine, less ethanolamine phosphoglycerides and much less sphingomyelin than C21. When incubated with 32Pi both cell lines incorporated comparable amounts of radioactivity into total phospholipids. In NIE, phosphatidylcholine contained much more and phosphatidylinositol and phosphatidic acid somewhat less label as compared to C21. The presence in the incubation medium of either norepinephrine or carbamylcholine failed to elicit stimulation of 32P incorporation into any phospholipid class.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract— The levels of cerebrosides in neural tissues of adult mice were determined by densitometry of cerebroside spots on charred thin-layer chromatograms of washed total lipid extracts. Values for brain, spinal cord and peripheral nerves were 9·2, 33·0 and 36·9 mg/g of tissue, respectively. In adult Quaking mice these values were 6·4, 24 and 35 % of normal, respectively. Normal levels in brain, spinal cord and peripheral nerve of 21-day-old mice were 3·10, 13·5 and 17·8 mg/g, respectively. In 21-day-old Quaking mice the levels were reduced to 16,21 and 57% of normal, respectively. Biosynthesis of psychosine (galacto-sylsphingosine) by homogenates of Quaking brain, spinal cord and peripheral nerve, respectively, was 18, 24 and 42% of the normal rates at 21 days after birth and 16, 66 and 60% of the normal rates at 94 days. Our results suggest a quantitative relationship between the rate of formation of psychosine in vitro and the rate of accumulation of cerebrosides. in vivo. Biosynthesis of lactosylceramide was not reduced in homogenates of brain and spinal cord from Quaking mice. Cerebroside levels in normal and Quaking spinal cord and in normal brain increased 2- to 3-fold after 21 days of age, but in Quaking brain there was little or no increase.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: —This report deals with some properties of the enzyme from rat brain, which catalyses in vitro the formation of lactosylceramide, a probable precursor of the gangliosides, from UDP-galactose and glucosylceramide. The enzyme is present in microsomes, mitochondria and synaptosomes, the latter having the highest specific activity, and appears to be firmly bound to the membranes of these particles. The enzymic activity is optimal at pH 6·8 and requires the presence of Mn2+.Lactosylceramide, the product of the reaction, was tentatively identified by its elution pattern from a Florisil column, its resistance to mild alkaline hydrolysis, thin-layer co-chromatography with authentic standards in six solvent systems, and location of the radioactivity in the galactose portion of the product obtained after incubation of labelled UDP-galactose with unlabelled glucosylceramide and in the glucose portion after incubation of glucose-labelled glucosylceramide with unlabelled UDP-galactose.The activity of this enzyme, per unit of brain weight, was found to be highest at birth and to decrease gradually thereafter. A similar age distribution was observed for another galactosyltransferase, the one which catalyses the formation of ganglioside GM1 from Tay-Sachs’ganglioside. In contrast, the activity of a third galactosyltransferase, which catalyses the formation of psychosine, and thus possibly is related to the increase of cerebrosides during myelination, is negligible during the first week and maximal about 20 days after birth.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
11Shah, I. R. ; Uma, S. ; Ramakrishnan, C. V. ; Hauser, G.
Oxford, UK : Blackwell Publishing Ltd
Published 1984Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Female rats were allowed to consume ethanol during gestation and lactation, and brain polyphosphoinositides of the 21-day-old pups were quantified. Ethanol intake prevented the disappearance of the metabolically labile pools of phosphatidylinositol-4-phosphate and phosphatidylinositol-4,5-bis-phosphate, which are rapidly degraded in the control group. In contrast, preweaning undernutrition left the size of these pools virtually unchanged, indicating a differential effect of the two nutritional regimens. Key Words: Polyphosphoinositides—Labile pools—Ethanol—Brain of offspring—Phosphati-dylinositol - 4 - phosphate—Phosphatidylinositol - 4,5 -bis-phosphate—Ethanol feeding—Undernutrition (preweaning). Shah I. R. et al. Effect of ethanol on rat brain polyphosphoinositides.Type of Medium: Electronic ResourceURL: -
12Weninger, M. ; Aue-Hauser, G. ; Scheiber, V.
Baltimore : Periodicals Archive Online (PAO)
Published 1976Staff ViewISSN: 0018-7143Topics: BiologyURL: -
13Staff View
ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0005-2760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0005-2760Keywords: (Rat pineal gland) ; Lipid metabolism ; Phospholipid-CMP metabolism ; PropranololSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: