Search Results - (Author, Cooperation:G. Casey)

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  1. 1
    A. G. Hinch ; A. Tandon ; N. Patterson ; Y. Song ; N. Rohland ; C. D. Palmer ; G. K. Chen ; K. Wang ; S. G. Buxbaum ; E. L. Akylbekova ; M. C. Aldrich ; C. B. Ambrosone ; C. Amos ; E. V. Bandera ; S. I. Berndt ; L. Bernstein ; W. J. Blot ; C. H. Bock ; E. Boerwinkle ; Q. Cai ; N. Caporaso ; G. Casey ; L. A. Cupples ; S. L. Deming ; W. R. Diver ; J. Divers ; M. Fornage ; E. M. Gillanders ; J. Glessner ; C. C. Harris ; J. J. Hu ; S. A. Ingles ; W. Isaacs ; E. M. John ; W. H. Kao ; B. Keating ; R. A. Kittles ; L. N. Kolonel ; E. Larkin ; L. Le Marchand ; L. H. McNeill ; R. C. Millikan ; A. Murphy ; S. Musani ; C. Neslund-Dudas ; S. Nyante ; G. J. Papanicolaou ; M. F. Press ; B. M. Psaty ; A. P. Reiner ; S. S. Rich ; J. L. Rodriguez-Gil ; J. I. Rotter ; B. A. Rybicki ; A. G. Schwartz ; L. B. Signorello ; M. Spitz ; S. S. Strom ; M. J. Thun ; M. A. Tucker ; Z. Wang ; J. K. Wiencke ; J. S. Witte ; M. Wrensch ; X. Wu ; Y. Yamamura ; K. A. Zanetti ; W. Zheng ; R. G. Ziegler ; X. Zhu ; S. Redline ; J. N. Hirschhorn ; B. E. Henderson ; H. A. Taylor, Jr. ; A. L. Price ; H. Hakonarson ; S. J. Chanock ; C. A. Haiman ; J. G. Wilson ; D. Reich ; S. R. Myers
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa, Western/ethnology ; African Americans/*genetics ; Alleles ; Amino Acid Motifs ; Base Sequence ; Chromosome Mapping ; Crossing Over, Genetic/*genetics ; Europe/ethnology ; European Continental Ancestry Group/genetics ; Evolution, Molecular ; Female ; Gene Frequency ; Genetics, Population ; Genome, Human/*genetics ; Genomics ; Haplotypes/genetics ; Histone-Lysine N-Methyltransferase/chemistry/genetics/metabolism ; Humans ; Male ; Molecular Sequence Data ; Pedigree ; Polymorphism, Single Nucleotide/genetics ; Probability
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Type of Medium:
    Online
    Publication Date:
    2023
    Keywords:
    Impfung ; Wirkungsgrad ; Studium ; Bachelor-Studiengang ; Effektivität
    In:
    The journal of economic education, Bd. 54 (2023) H. 3, S. 289-300, 2152-4068
    Language:
    English
    FIS Bildung Literaturdatenbank
  3. 3
    Staff View
    Type of Medium:
    article
    Publication Date:
    2014
    Keywords:
    Schulbuch ; Wirtschaftserziehung ; Begutachtung ; Inhalt ; Publizieren
    In:
    The journal of economic education, Bd. 45 (2014) H. 2, S. 159-165, 0022-0485
    2152-4068
    Language:
    English
    FIS Bildung Literaturdatenbank
  4. 4
    Staff View
    Publication Date:
    2018-03-15
    Publisher:
    American Chemical Society (ACS)
    Print ISSN:
    0002-7863
    Electronic ISSN:
    1520-5126
    Topics:
    Chemistry and Pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    CASEY, G. A. ; HUNT, H. M. ; PADDON, A. C. ; WILCOCK, P. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1365-2214
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Psychology
    Notes:
    Summary A series of workshops for staff working with profoundly handicapped children was organized, the main concern of which was to improve the teaching approaches with such a population. The workshops were the result of an innovative attempt by the British Psychological Society's Standing Committee on Handicap to apply current knowledge of the real life problems of work settings in schools or hospitals where children are educated. The workshops covered a period of 3 months with approximately one term between the first and second. Participants attended in pairs, one member of each pair being either a clinical or educational psychologist, and a variety of problems presented by the children were tackled. This paper attempts to describe the structure and operation of the workshops, to evaluate their outcome, and to suggest ideas for the future of such an approach.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    HAWES, CATHERINE S. ; SUSKIN, H. A. ; KALIONIS, B. ; MUELLER, U. W. ; CASEY, G. ; HALL, J. ; RUDZKI, Z.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1994
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    ANDREWS, A. E. ; CASEY, G. J. ; RODGERS, S. E. ; FLOWER, R. L. P. ; RUDZKI, Z.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2516
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary. Approximately one-third of haemophilia B cases are described as isolated due to their occurrence in families with no prior history of the disorder. In this report, two families with isolated haemophilia B were studied by the standard method of restriction fragment length polymorphism (RFLP) analysis coupled with factor IX activity and antigen levels with the aim of achieving carrier diagnoses. The limitations of using this approach in the determination of carrier status were highlighted by diagnostic problems arising in both families. The problems included difficulty in interpreting bioassay results, homozygosity for the RFLP marker in a key family member and the possibility of germline mosaicism. Unequivocal carrier diagnosis in the two families was ultimately achieved by direct mutation analysis.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Casey, P. A. ; Casey, G. ; Fleisch, H. ; Russel, R. G. G.
    Springer
    Published 1972
    Staff View
    ISSN:
    1420-9071
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Zusammenfassung Zwei Phosphatasehemmer (Polyphloretinphosphat und Polyoestradiolphosphat), ein Polyphosphat (Hexametaphosphat) und ein Diphosphonat (Ethan-1-hydroxy-1,1-diphosphonat) wurden auf ihre Fähigkeit untersucht, Verkalkungen zu verhindern, welche in der Haut, der Aorta und den Nieren von Ratten durch Dihydrotachysterol (DHT) hervorgerufen wurden. Das Diphosphonat erwies sich als der stärkste Hemmer; dann folgten das Polyphosphat und die zwei Phosphatasehemmer. Die Phosphatasehemmer wurden zusätzlich auf ihre Fähigkeit geprüft, die Calciumphosphat-Ausfällung in vitro zu verlangsamen. Polyphloretinphosphat besitzt diese Fähigkeit bei Konzentrationen von 10−5 M und mehr; Polyoestradiolphosphat ist unwirksam.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Reeves, B.R. ; Casey, G. ; Harris, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Reeves, B.R. ; Casey, G. ; Honeycombe, J.R. ; Smith, S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Foxes were vaccinated orally (by bait), gastrically (by stomach tube) and by sacrification with a vaccinia recombinant virus expressing the rabies glycoprotein. Neutralizing antibodies against rabies virus were detected at two weeks postvaccination in 8/8 foxes in the bait-fed group, in 3/6 foxes inoculated by stomach tube and in 2/2 of the scarified foxes. After challenge at three months postvaccination with street rabies virus, all foxes that had developed antibodies were protected. The high rate of seroconversion, high levels of antibodies, and resistance to challenge suggest that this recombinant virus might be a suitable vaccine for oral immunization of foxes against rabies.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-0533
    Keywords:
    Key words Rabies ; Skunk ; Immunohistochemistry ; Viral transit in fiber tracts ; Pathogenesis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Twenty-four striped skunks were inoculated intramuscularly (long digital extensor muscle of right pelvic limb) with street rabies virus. Groups of two clinically normal skunks were killed at various times after inoculation; skunks that developed rabies were killed in early stages of the clinical signs. Four clinically normal skunks (numbered 1–4) had slight infection in lumbar spinal ganglia, spinal cord and brain. These four skunks were used for detailed immunohistochemical (rabies antigen) studies that included examination of sections from every segment of the spinal cord, most of the spinal ganglia from the 2nd cervical to the 2nd coccygeal (sections at 25-μm intervals of lumbar, sacral and coccygeal ganglia) and brain (sections at 50-μm intervals). In skunks 1–4, there was increasing distribution of antigen-containing neurons that was not correlated with the time elapsed since inoculation. In three skunks (nos. 1, 2 and 3), antigen-containing neurons were predominantly in caudal regions of the spinal cord, caudal right lumbar and sacral spinal ganglia and certain nuclei/regions of the brain (medial reticular formation, right interpositus and lateral vestibular nuclei, left red nucleus, left motor cortex, and left reticular nucleus of the thalamus). Skunk 4 had more extensive infection than skunks 1–3, but the previous pattern was still evident. The results are consistent with viral entrance into the lumbar spinal cord, initial replication mainly at the L2 and L3 levels, local spread in the cord by propriospinal neurons and early transit to the brain via long ascending and descending fiber tracts (bypassing the grey matter of the rostral spinal cord). These mechanisms could provide for early and rapid dissemination in the brain before a significant immune response develops and could induce behavioral changes before the animal is incapacitated by extensive spinal cord infection. Based on the distribution of antigen-containing neurons, the tracts considered most likely to serve as viral transitways from spinal cord to brain include: rubrospinal, corticospinal, spinothalamic, spino-olivary, vestibulospinal and/or spinovestibular, reticulospinal and/or spinoreticular, cerebellospinal and/or spinocerebellar, and dorsal column pathways.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1432-0533
    Keywords:
    Key words Rabies ; Long incubation periods ; Skunk ; Polymerase chain reaction ; Immunohistochemistry
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract The striped skunk (Mephitis mephitis) is a host of rabies in large areas of Canada and the United States. In each of two experiments, equal numbers of skunks in two groups were inoculated intramuscularly with low doses of a field strain of rabies virus (street rabies virus). In each experiment, skunks in one group surviving to 2 months were killed at this time and selected tissues were used for examination by the polymerase chain reaction (PCR) method or by immunohistochemistry for rabies antigen. Results of detailed examinations using PCR technology (experiment 1) indicated that muscle at the inoculation site contained viral RNA at 2 months postinoculation, when other relevant tissues on the route of viral migration and early entrance into the central nervous system were negative. The cellular location of virus/antigen, as determined immunohistochemically in experiment 2, was striated muscle fibers and fibrocytes. Our results indicate a major role of muscle (tissue) infection at the inoculation site in the long incubation period of rabies in skunks. These and related findings will be useful in rabies control and, if applicable to other species, will be relevant in postexposure treatment.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Rank, G. H. ; Casey, G. P. ; Xiao, W. ; Pringle, A. T.
    Springer
    Published 1991
    Staff View
    ISSN:
    1432-0983
    Keywords:
    Saccharomyces cerevisiae ; Bakers' and lager yeast ; Chromosomal and 2 μm DNA polymorphism
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Summary Seven strains of bakers' yeast were obtained as a representative sample of the Spanish baking industry. The nuclear genome was monitored for polymorphism by transverse alternating field electrophoresis (TAFE) and restriction maps of 2 μm DNA were produced. All seven strains were uniquely different when evaluated by their total chromosomal lengths whereas only two 2 μm variants were defined. There was no apparent correlation between chromosomal and plasmid polymorphism. The extensive chromosomal polymorphism within one 2 μm DNA type indicates the rapid and relatively recent evolution of the nuclear genome. The hybrid origin (S. cerevisiae-S.monacensis) of lager yeast was critically evaluated by TAFE analysis of S. cerevisiae and S. carlsbergensis chromosomes. The absence of corresponding S. cerevisiae chromosomes III and XIII in S. carlsbergensis argued against the hybrid origin of lager strains. We discuss limitations of the hybrid origin hypothesis of industrial yeasts and propose that the molecular coevolution observed in 2 μm DNA serves as a useful additional mechanism for rationalization of some of the structural polymorphism of the nuclear genome.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary A new recombinant rabies vaccine (human adenovirus 5 containing the rabies glycoprotein gene) was given to striped skunks (Mephitis mephitis) and red foxes (Vulpes vulpes). Groups of skunks received the vaccine in baits, by direct instillation into the mouth, or intramuscularly. Foxes were given vaccine by direct instillation into the oral cavity (DIOC). Selected groups of vaccinated skunks and foxes were challenged with street rabies virus. There were high rates of seroconversion (generally with high antibody titers) in both foxes and skunks, with survival of all challenged vaccinated animals (all challenge controls developed rabies). In skunks, vaccine given DIOC was effective over a broad range of doses (108.7, 107.6 and 106.4 median tissue culture infective doses). There was no evidence of pathogenic effects. The results indicate that this adenovirus recombinant has considerable potential as a wildlife oral rabies vaccine.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Casey, G. P. ; Magnus, C. A. ; Ingledew, W. M.
    Springer
    Published 1983
    Staff View
    ISSN:
    1573-6776
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Summary Supplementation of high gravity brewing worts with 0.8% yeast extract, 24 ppm ergosterol and 0.24% (v/v) Tween 80 can result in the production of 〉14% (v/v) alcohol at 14°C within 5 days. Unsupplemented worts require up to 2 weeks to end ferment. Overcoming nitrogenous and lipid nutritional deficiencies results in substantial increases in cell mass production, decreased fermentation times and increased ethanol. It can be concluded that brewers yeast are tolerant to levels of ethanol previously associated only with winery and distilling yeasts, and that they do not require genetic manipulation or strain improvement to become tolerant to 14–16% ethanol.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses