Search Results - (Author, Cooperation:D. G. Anderson)
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1Latest Papers from Table of Contents or Articles in PressM. Ma ; L. Guo ; D. G. Anderson ; R. Langer
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-01-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Biomimetics ; Borates/chemistry ; *Electric Power Supplies ; *Electricity ; Ethylene Glycols/chemistry ; Muscle Contraction ; Polymers/*chemistry ; Propylene Glycols/chemistry ; Pyrroles/*chemistry ; *WaterPublished by: -
2Latest Papers from Table of Contents or Articles in PressW. Xue ; S. Chen ; H. Yin ; T. Tammela ; T. Papagiannakopoulos ; N. S. Joshi ; W. Cai ; G. Yang ; R. Bronson ; D. G. Crowley ; F. Zhang ; D. G. Anderson ; P. A. Sharp ; T. Jacks
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; *CRISPR-Cas Systems ; Cell Transformation, Neoplastic/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Female ; *Genes, Tumor Suppressor ; Genes, p53/genetics ; Genetic Engineering/*methods ; Hepatocytes/metabolism/pathology ; Lipid Metabolism ; Liver/cytology/*metabolism/pathology ; Liver Neoplasms/genetics/metabolism/pathology ; Mice ; Molecular Sequence Data ; Mutagenesis/*genetics ; Mutation/*genetics ; Oncogenes/*genetics ; PTEN Phosphohydrolase/genetics ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; beta Catenin/geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressKhan, O. F., Kowalski, P. S., Doloff, J. C., Tsosie, J. K., Bakthavatchalu, V., Winn, C. B., Haupt, J., Jamiel, M., Langer, R., Anderson, D. G.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-28Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
4Articles: DFG German National LicensesAnderson, D. G. ; Lopez, G. A. ; Bewernick, D. ; Brazal, S. ; Ponder, J. ; Russom, J. M.
Springer
Published 1990Staff ViewISSN: 1432-0878Keywords: Hibernation ; Ultrastructure ; Plasma renin activity ; Renal changes ; Spermophilus lateralis (Rodentia)Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Chronological changes in renal glomerular morphology and plasma renin activity were investigated during active and hibernating periods in the golden-mantled ground squirrel Spermophilus lateralis. The objective of this study was to determine whether the glomerular endothelium, visceral epithelium (podocytes), basement membrane, mesangial cells, proximal convoluted tubule cells and plasma renin activity exhibit measurable sequential differences between as well as within active and hibernating states at various time points. Limitations in the size of the experimental population prevented an evaluation of changes in these parameters during other important periods such as periodic arousal between hibernation bouts. In this study, glomerular endothelial pore number and epithelial filtration slit number significantly decreased by early hibernation when compared to those during summer activity, and then they increased back toward summer levels by late hibernation. In contrast, podocytic pedicel width along the glomerular basement membrane increased from summer activity to early hibernation, before significantly decreasing again by late hibernation. Mesangial cell and proximal convoluted tubule cell activity appeared increased during hibernation as compared to summer activity, whereas the width of the glomerular basement membrane showed no significant alterations throughout. Plasma renin activity significantly increased during early hibernation and mid-hibernation when compared to summer levels but had decreased by late hibernation toward summer values. The glomerular and plasma renin activity changes observed in this study clearly illustrate the drastic structural and functional adjustments which hibernating species make during torpor and also correlate well with the reported decrease in renal perfusion pressure and urine formation during hibernation. The observed morphological changes during hibernation do not appear to be temperature-dependent, because significant alterations in most of the parameters studied occurred during this period despite the fact that cold-room temperatures were kept constant throughout. The chronological approach to this study and its morphometric evaluation represent a pilot attempt at accurately documenting these changes during two critical states in the hibernator's cycle and may eventually lead to the characterization of these changes during the entire circannual cycle.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1573-6857Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Alcohol dehydrogenase (ADH) activity variation in male flies taken directly from seven natural populations ofDrosophila melanogaster is largely accounted for by segregation of alleles at theAdh structural gene locus. There was little overlap in the ADH activities ofAdh F andAdh s homozygotes. Body weights varied only slightly betweenAdh genotypes and contributed little to ADH variation. Between and within population variation in ADH activity and ADH protein in flies in the wild is mainly due to the relative frequencies ofAdh F andAdh s.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0030-4921Keywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The tetraphenyl-metal, hexaphenyl-dimetal, and triphenylchloro-metal derivatives of the Group IV elements were examined using 13C NMR methods. Chemical shifts and metal-carbon coupling constants were obtained for all compounds studied.Additional Material: 4 Tab.Type of Medium: Electronic ResourceURL: