Search Results - (Author, Cooperation:C. Royo)

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  1. 1
    X. S. Puente ; S. Bea ; R. Valdes-Mas ; N. Villamor ; J. Gutierrez-Abril ; J. I. Martin-Subero ; M. Munar ; C. Rubio-Perez ; P. Jares ; M. Aymerich ; T. Baumann ; R. Beekman ; L. Belver ; A. Carrio ; G. Castellano ; G. Clot ; E. Colado ; D. Colomer ; D. Costa ; J. Delgado ; A. Enjuanes ; X. Estivill ; A. A. Ferrando ; J. L. Gelpi ; B. Gonzalez ; S. Gonzalez ; M. Gonzalez ; M. Gut ; J. M. Hernandez-Rivas ; M. Lopez-Guerra ; D. Martin-Garcia ; A. Navarro ; P. Nicolas ; M. Orozco ; A. R. Payer ; M. Pinyol ; D. G. Pisano ; D. A. Puente ; A. C. Queiros ; V. Quesada ; C. M. Romeo-Casabona ; C. Royo ; R. Royo ; M. Rozman ; N. Russinol ; I. Salaverria ; K. Stamatopoulos ; H. G. Stunnenberg ; D. Tamborero ; M. J. Terol ; A. Valencia ; N. Lopez-Bigas ; D. Torrents ; I. Gut ; A. Lopez-Guillermo ; C. Lopez-Otin ; E. Campo
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    3' Untranslated Regions/genetics ; Alternative Splicing/genetics ; B-Cell-Specific Activator Protein/biosynthesis/genetics ; B-Lymphocytes/metabolism ; Carrier Proteins/genetics ; Chromosomes, Human, Pair 9/genetics ; DNA Mutational Analysis ; DNA, Neoplasm/genetics ; Enhancer Elements, Genetic/genetics ; Genomics ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/*genetics/metabolism/pathology ; Mutation/*genetics ; Nerve Tissue Proteins/genetics ; Nuclear Proteins/genetics ; Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics ; Receptor, Notch1/genetics/metabolism ; Transcription Factors/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
    ROYO, C. ; PARES, D.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2494
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    In field experiments conducted over 2 years in Mediterranean conditions, five winter and five spring triticales were evaluated for forage and grain production in the same cropping season. The experiments had two treatments, namely harvesting for grain only, and dual-purpose forage and grain production. In the latter treatment, forage was cut when the first node was detectable (Zadoks' stage 31), without removing the apical meristems. Grain was harvested when ripe (Zadoks' stage 92) in both cut and uncut plots.Environmental conditions affected grain production and protein content more than forage yield and quality. Winter triticales yielded about 43% more forage than spring types, but after forage removal the spring types yielded about 36% more grain than winter triticales.Reductions in grain yield after clipping were more pronounced in winter (32%) than in spring (19%) types. Forage crude protein content was significantly higher in the spring types studied (24.6%) than in the winter types (23.5%), the opposite being true for fibre content (20.7 and 21.6% respectively). Grain crude protein content did not differ between grain and dual-purpose treatments, but was higher in the spring triticales (12.8%) than in the winter types (11.9%). There was more variability for the measured traits within the winter triticales studied than within the spring types.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    ROYO, C. ; ROMAGOSA, I.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2494
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    The effect of forage removal on the growth of five winter and five spring triticale genotypes was studied in 1992 and 1993 in field experiments in north-eastern Spain. When cut, winter triticales produced more biomass and leaf area than spring types owing to their higher tillering capacity. The leaf area index (LAI) at anthesis was similar in both groups in both clipped and uncut plots, but spring triticales had a greater leaf area on the main stem than winter types. Winter types had a greater leaf area on the tillers than spring types. Spring and winter types had a similar physiological response to forage removal, except for modifications in flag leaf area. In spring types triticale flag leaf area was reduced by clipping, whereas in winter types flag leaf area was increased. Forage removal resulted in less dry-matter accumulation in all plant parts, maximum weight of the plant being reduced by about 20% and the rate of growth by around 13%. LAI at anthesis decreased by 37% as a result of clipping, and the leaf area duration from anthesis to maturity decreased by 36%. The duration of growth increased after clipping. Heading, anthesis and maturity dates were delayed by clipping, but grain filling duration was not affected.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Royo, C.

    Oxford, UK : Blackwell Science Ltd
    Published 1997
    Staff View
    ISSN:
    1365-2494
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Two field experiments were carried out under irrigation and high fertility in northeastern Spain during 1992 and 1993. Ten triticale genotypes, five of spring growth habit and five winter types, were tested for their suitability for both forage and grain. Forage removal reduced grain yield per plant by about 17%, but did not have any significant effect on plant density, ear density or tiller number per plant. Tiller mortality was greater in winter types (65%) than in spring triticales (25%), but was not affected by cutting. Decreases in grain yield following cutting could be attributed to reductions in the number of grains per spike and kernel weight. Cutting decreased the number of grains per spike by about 9% by reducing the two components, spikelets per head and grains per spikelet. The average spike length was 10·6 cm in the uncut treatment and 10·1 cm in the dual-purpose plots. Cutting reduced thousand kernel weight by about 7% in winter triticales, and around 10% in spring types, both in main spike and in first tiller. The effect of a forage harvest on yield components was in general similar for both types of triticale. Cutting when jointing commenced induced changes in the relative importance of yield components influencing future grain yield. The yield components reduced by cutting were the most important contributors to grain yield after forage removal.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Rharrabti, Y. ; Villegas, D. ; Garcia del Moral, L. F. ; Aparicio, N. ; Elhani, S. ; Royo, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2001
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    The unpredictability of the Mediterranean climate causes fluctuations in wheat yield and quality, but offers the opportunity for obtaining high-quality durum wheat in terms of grain protein content. Twenty-five durum wheat genotypes were grown under irrigated and rainfed conditions at each of two latitudes in Spain during 1998 and 1999. Differences between latitudes in grain protein content and chlorophyll content in the flag leaf were attributable to nitrogen fertilization management. Cycle length until anthesis was less affected by the environment than grain-filling duration, and was longer under irrigated conditions than in the rainfed sites. A negative asymptotic curve was the best equation to fit the relationship between yield and protein content, suggesting that yield improvements in fertile environments may be attained with negligible reductions in protein content. ‘Jabato’, ‘Waha’, ‘Lagost-3’, ‘Massara-1’ and ‘Vitŕon’ showed medium to high yield, yield stability and high protein content. Chlorophyll content in the flag leaf, measured at anthesis with the soil-plant analysis development (SPAD) portable field unit, may be useful for the fast and cheap detection of durum wheat genotypes with high grain protein content in drought-stressed Mediterranean environments.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Royo, C. ; Soler, C. ; Romagosa, I.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    A collection of 299 secondary hexaploid triticale cultivars and advanced breeding lines from 18 countries, which were considered a representative sample of the existing diversity, was evaluated for morphological and agronomical characters with autumn planting at Lleida, Spain, from 1988 to 1991. The entries were classified as having winter (84) or spring (215) growth habit and among this latter group were complete (73) or substituted (147) types according to CIMMYT's terminology. Winter and spring triticales were grouped by cluster and principal component analyses. Winter triticales were taller with longer growth cycles, longer spikes, and more spikelets per spike than spring types. At early stages they also had prostrate growth. Spring-substituted types were separated from complete material. As a group, spring-substituted triticales differed more from winter types than the spring complete genotypes, which showed intermediate characteristics. Complete types of spring habit had tendency to be taller, with longer spikes, more spikelets per spike and bigger and heavier grains than substituted triticales. Greater variation in morphological and agronomical parameters was detected among winter triticales followed by the complete-spring group.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    ROYO, C. ; MONTESINOS, E. ; MOLINA-CANO, J. L. ; SERRA, J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1365-2494
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    In field experiments conducted over 2 years, triticale was compared with barley, bread wheat and oats for its dual-purpose (forage and grain) capability.The effect of spring forage removal on grain yield ranged from small yield increases (in the triticale and barley genotypes that otherwise lodged) to a 53% decrease, and was dependent on species, genotype, stage of development when cut, and time for recovery before grain harvest. A key factor influencing grain yield after early cutting was the number of spikes that developed.The complete types of triticale were better than the one substituted type tested for dual purpose but, as there is variability among them, selection for good mixed aptitude is possible.The production of the best triticale averaged over 2 years 3 t of forage DM ha-1 (with 684 kg of crude protein ha-1) and then 4–3 t of grain ha-1. In this instance, neither the grain yield nor the number of spikes per plant were reduced after clipping, in spite of the fact that the shoot apices were removed.Plant height and lodging were reduced by a forage cut. In triticale, the number of days to heading was increased even more when the cut was late, but no effect was observed in barley.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Royo, C. ; Rodriguez, A. ; Romagosa, I.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Adaptation of seven complete and twelve substituted triticales to specific soil types has been studied, based on a series of twenty trials carried out in 1989 and 1990 across Spain. The nature of the GE interaction for grain yield was revealed by means of the additive main effects multiplicative interaction (AMMI) model and using the soil pH at the different sites as linear covariate. The percentage of the variability explained by the first principal component axis of the AMMI model was 72 and 65 % for the two years, suggesting a specific pattern of adaptation. Soil pH was the single most important environmental factor to explain the adaptation of complete and substituted types. Complete triticales outyielded substituted genotypes in the majority of sites. Triticale adaptation to acid and alkaline soils seems to be largely controlled by the single wheat/rye chromosome 2D(2R) substitution, for which both types differ. Complete triticales seem better adapted to the acid soils, whereas substituted types are, in general, more suited to alkaline soils.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Molina-Cano, J. L. ; Montoya, J. L. ; Echarte, J. ; Royo, C. ; Serra, J. ; Marin-Sanchez, J. P.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1992
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Twenty-four near-isogenic barley lines, with a cv.‘Pallas’ background, carrying different mildew resistance genes were subjected in 1987, 1989 and 1990 to natural infection by the pathogen at several different and contrasting Spanish sites in order to study its virulence. The virulence genes proved to be geographically grouped into three regions: western (Valladolid), southern (Sevilla) and northern and northeastern (Navarra, Lleida and Girona). The mildew population of Lleida was more variable when compared with Navarra and Valladolid. Overall, the most effective resistance genes were: Ml-a13 + Ml-(Ru3), mlo and Ml-(1402).
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Trujillo, A.J. ; Royo, C. ; Ferragut, V. ; Guamis, B.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Goat cheeses were made from pasteurized (72 °C, 15 s) and high-pressure (HP)-treated milk (500 MPa, 15 min, 20 °C). At 45 days of ripening, cheeses made from both types of milk were similar in moisture, quality, electrophoretic profiles, water-soluble nitrogen, and total free fatty acid contents. Cheeses made from HP-treated milk had higher pH and salt, matured more quickly, as determined by formation of total free amino acids, and developed strong flavors. Reverse-phase high-performance liquid chromatography showed differences between the peptide profiles of the cheeses. Differences in small peptides and free amino acids indicated a higher extent of proteolysis in cheeses made from HP-treated milk.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    0378-4290
    Keywords:
    Cutting stage ; Fodder ; Grain ; Triticale
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1432-1238
    Keywords:
    Key words Sucralfate ; Gastric intramucosal pH ; Tonometry ; Critically ill patients
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Objective: To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi). Design: Non-randomized observational study. Setting: General intensive care unit of a teaching hospital. Patients: Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube. Interventions: Tonometer placement and sucralfate administration. Measurements and main results: We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 ± 1.7, 2 h 6.3 ± 1.7, 4 h 6.3 ± 1.7; pHi: basal 7.35 ± 0.13, 2 h 7.36 ± 0.12, 4 h 7.36 ± 0.12). Conclusions: Sucralfate does not affect the tonometric measurement of PCO2i and pHi.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    1432-1238
    Keywords:
    Key words Ranitidine ; Gastric intramucosal pH ; Tonometry ; Critically ill patients
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Objective: To determine whether ranitidine a) increases the values of gastric intramucosal pH (pHi) in critically ill patients, as determined by tonometry; b) reduces the variability of these measurements. Design: Prospective, double blind, randomized, placebo-controlled study. Setting: General Intensive Care Unit of a teaching hospital. Patients: Twenty-five critically ill, mechanically ventilated patients requiring arterial catheter and nasogastric tube. Interventions: Tonometer placement; blind, random administration of intravenous ranitidine (50 mg) or placebo. Measurements and main results: Tonometer saline PCO2 (PCO2i), arterial blood gases, gastric juice pH and pHi were determined immediately before, and 2, 4, 6 and 8 h after, ranitidine (12 patients) or placebo (13 patients). Ranitidine significantly increased gastric juice pH, but did not affect PCO2i or pHi; pHi was 7.34 ± 0.14 before ranitidine, and 7.30 ± 0.12, 7.31 ± 0.11, 7.31 ± 0.14 and 7.31 ± 0.12 – 2, 4, 6 and 8 h, respectively, after ranitidine administration (p = 0.55). Ranitidine did not modify the coefficients of variation of PCO2i or pHi, either. No significant changes in gastric juice pH, PCO2i or pHi were observed in the placebo group. Conclusions: In critically ill patients, ranitidine has no effect on pHi values, and does not increase the reproducibility of pHi measurements.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Molina-Cano, J. L. ; Togores, F. Roca ; Royo, C. ; Pérez, A.
    Springer
    Published 1989
    Staff View
    ISSN:
    1432-2242
    Keywords:
    Barley ; Malting quality ; Germination speed ; β-Glucans ; Mutation breeding
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Summary Mutation breeding has been used to improve the speed of germination in the high-yielding spring barley variety Troubadour. Five mutants were selected which combined fast germination and good agronomic performance. Two of these mutants yielded significantly more than did Troubadour over eight environments, and showed a clear improvement in their malting quality through an increase in extract yield. The improvement in malting quality appeared to be due to a decrease in the β-glucan content, which seemed to enhance the germination speed and thus the starch degradation. The improvement in grain yield is postulated to be due to a better early growth caused by the enhanced germination speed. All the described changes could theoretically be explained by a single mutation event in each of the mutant genotypes, affecting the quantity of β-glucans present in the endosperm.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Over the last 16 years, 202 fetal tissue transplants have been performed in our department to treat 29 patients with severe inborn errors of metabolism without immunodeficiency, 26 patients with congenital and severe immunodeficiency diseases, and 2 patients with severe aplastic anaemia. The actuarial survival curve of patients with inborn errors of metabolism treated with fetal liver transplantation shows a 12-year survival of 77%. The condition of many of these patients has been improved by the treatment, but transplantation has had to be repeated in order to maintain clinical amelioration. Enzyme levels were not significantly and durably increased in peripheral blood but the quantities of substrates detected in sera and urines were significantly reduced and tissue deposits were stabilized.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Royo, C. ; Menéndez, M. ; Santamaría, J.
    Springer
    Published 1991
    Staff View
    ISSN:
    1588-2837
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Abstract Проведены кинетические исследования регенерирования коммерческих катализаторов Cr2O3/Al2O3 с помощью сжигания кокса. Обнаружено, что скорость реакции на несколько порядков выше, чем для катализаторов без переходных металлов.
    Notes:
    Abstract A kinetic study has been carried out of the regeneration of a commercial Cr2O3/Al2O3 catalyst by coke combustion. The results obtained show that the reaction rate is several orders of magnitude higher than that obtained on catalysts without transition metals.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1588-2837
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Abstract Использовали модель типа таблетки-зерна в рассмотрении влияния высоких скоростей реакций на температурные профили, образующиеся в ходе регенерирования зауглероженных катализаторов. На основе полученных данных обсуждают возможность фальсификации кинетических данных.
    Notes:
    Abstract A grain-pellet model has been used to study the effect of high reaction rates upon the temperature profiles developed during regeneration of coked catalyst particles. The possibility of falsification of kinetic data is discussed in view of the results obtained.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses