Search Results - (Author, Cooperation:C. Richter)

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  1. 1
    M. N. Hopkinson ; C. Richter ; M. Schedler ; F. Glorius
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-06-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    L. Li ; C. Richter ; S. Paetel ; T. Kopp ; J. Mannhart ; R. C. Ashoori
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-05-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2014-06-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Atlantic Ocean ; *Climate Change ; Mediterranean Sea ; Paleontology ; *Seawater ; *Water Movements
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    L. Kuerten, E. Fillis-Tsirakis, C. Richter, J. Mannhart, and H. Boschker
    American Physical Society (APS)
    Published 2018
    Staff View
    Publication Date:
    2018-08-16
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Superfluidity and superconductivity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    H. Palike ; M. W. Lyle ; H. Nishi ; I. Raffi ; A. Ridgwell ; K. Gamage ; A. Klaus ; G. Acton ; L. Anderson ; J. Backman ; J. Baldauf ; C. Beltran ; S. M. Bohaty ; P. Bown ; W. Busch ; J. E. Channell ; C. O. Chun ; M. Delaney ; P. Dewangan ; T. Dunkley Jones ; K. M. Edgar ; H. Evans ; P. Fitch ; G. L. Foster ; N. Gussone ; H. Hasegawa ; E. C. Hathorne ; H. Hayashi ; J. O. Herrle ; A. Holbourn ; S. Hovan ; K. Hyeong ; K. Iijima ; T. Ito ; S. Kamikuri ; K. Kimoto ; J. Kuroda ; L. Leon-Rodriguez ; A. Malinverno ; T. C. Moore, Jr. ; B. H. Murphy ; D. P. Murphy ; H. Nakamura ; K. Ogane ; C. Ohneiser ; C. Richter ; R. Robinson ; E. J. Rohling ; O. Romero ; K. Sawada ; H. Scher ; L. Schneider ; A. Sluijs ; H. Takata ; J. Tian ; A. Tsujimoto ; B. S. Wade ; T. Westerhold ; R. Wilkens ; T. Williams ; P. A. Wilson ; Y. Yamamoto ; S. Yamamoto ; T. Yamazaki ; R. E. Zeebe
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-08-31
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Altitude ; Atmosphere/chemistry ; Calcium Carbonate/*analysis ; *Carbon Cycle ; Carbon Dioxide/analysis ; Diatoms/metabolism ; Foraminifera/metabolism ; Geologic Sediments/chemistry ; Global Warming/history/statistics & numerical data ; History, 21st Century ; History, Ancient ; Marine Biology ; Oxygen/metabolism ; Pacific Ocean ; Seawater/*chemistry ; Temperature
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2018-08-18
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    0031-9007
    Electronic ISSN:
    1079-7114
    Topics:
    Physics
    Keywords:
    Condensed Matter: Electronic Properties, etc.
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2013-10-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Toxin molecules, such as Pseudomonas exotoxin A (PEA), kill a cell by inactivating the elongation factor-2 (EF-2) in the cytosol2'8, suggesting that mammalian cells can be genetically modified to produce and secrete targeted toxins by using a signal sequence to lead newly synthesized toxins into ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The nm23 complementary DNA was identified by differential hybridization to messenger RNA from K-1735 melanoma lines of varying metastatic potentials2; nm23 RNA levels were uniformly reduced in high metastatic potential rodent cell lines (Fig. la). Human infiltrating ductal breast carcinomas from ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1573-7217
    Keywords:
    recombinant immunotoxins ; erbB-2 ; pharmacokinetics ; toxicity
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The performance of OLX-209 indicates it should enter phase I clinical testing. OLX-209 is a recombinant toxin targeting theerbB-2 oncoprotein. The design of OLX-209 takes advantage of improvements in immunotoxin technology to produce a molecule that is smaller and more potent than a conventional chemically linked antibody-toxin conjugate. The targeting portion of OLX-209 is a single chain antibody structure derived from the anti-erbB-2 hybridoma, e23. This antibody has unusual specificity in that it does not bind to most normal tissue including peripheral nerve or kidney tissue. Preclinical testing showsin vitro activity against breast cancer cell lines in the pM range. Efficacy testing in five models of human cancer indicates that a dose of 43 µg/kg causes reproducible tumor regressions. Efficacy can be achieved on a variety of schedules of administration. The effective dose results in no measurable change in serum liver enzymes when delivered to mice or primates. The LD10 is over twice the effective dose in mice. The pharmacokinetics indicate a t1/2 of 50 minutes for both mice and cynomolgus monkeys. Serum concentrations of more than ten times those observed at the effective dose can be achieved in monkeys with no evidence of toxicity. Antigenicity of OLX-209 is surprisingly low. These results form the basis for the clinical testing phase for OLX-209.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Lung, Feng-Di T. ; King, C. Richter ; Roller, Peter P.
    Springer
    Published 1999
    Staff View
    ISSN:
    1573-3904
    Keywords:
    cyclic peptides ; inhibitors ; N-chloroacetyl peptide ; signal transduction ; solid-phase peptide synthesis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Summary One of the critical intracellular signaling pathways involves specific interactions between growth factor receptors and the adaptor protein Grb2. These interactions normally involve specific tyrosine phosphorylated regions in receptors and other cognate proteins. Following the lead of our recent findings that a phage library based non-phosphorylated disulfide linked 11-mer peptide inhibited such interactions, we report here the synthesis of novel redox-stable cyclic peptide analogs. These include thioether cyclized and backbone cyclized structures. The thioether analog was prepared under mild conditions from an N-terminally chloroacetylated and C-terminally cysteine extended peptide precursor. The thioether peptide showed equipotent binding affinity for the Grb2-SH2 domain (IC50=10–15 μM) when compared to the disulfide cyclized lead-peptide. The bioactive thioether linked peptide was demonstrated to offer advantages to the disulfide cyclized peptides under physiological conditions.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Lung, Feng-Di T. ; King, C. Richter ; Roller, Peter P.
    Springer
    Published 1999
    Staff View
    ISSN:
    1573-3904
    Keywords:
    cyclic peptides ; inhibitors ; N-chloroacetyl peptide ; solid-phase peptide synthesis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Abstract One of the critical intracellular signaling pathways involves specific interactions between growth factor receptors and the adaptor protein Grb2. These interactions normally involve specific tyrosine phosphorylated regions in receptors and other cognate proteins. Following the lead of our recent findings that a phage library based non-phosphorylated disulfide linked 11-mer peptide inhibited such interactions, we report here the synthesis of novel redox-stable cyclic peptide analogs. These include thioether cyclized and backbone cyclized structures. The thioether analog was prepared under mild conditions from an N-terminally chloroacetylated and C-terminally cysteine extended peptide precursor. The thioether peptide showed equipotent binding affinity for the Grb2-SH2 domain (IC50 = 10–15 μM) when compared to the disulfide cyclized lead-peptide. The bioactive thioether linked peptide was demonstrated to offer advantages to the disulfide cyclized peptides under physiological conditions.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    Type of Medium:
    Online
    Publication Date:
    2013
    Keywords:
    Kompetenz ; Hauptschule ; Realschule ; Lernaufgabe ; Physikunterricht
    In:
    Bernholt, Sascha (Hrsg.), Inquiry-based Learning - Forschendes Lernen., Kiel: IPN-Verlag (2013), S. 644-646, 978-3-89088-360-1
    Language:
    German
    FIS Bildung Literaturdatenbank
  15. 15
    Staff View
    Type of Medium:
    article
    Publication Date:
    2008
    Keywords:
    Erziehung ; Bewegung (Pol) ; Sozialerziehung ; Kinder- und Jugendsport ; Olympische Idee ; Schulsport ; Sport ; Sportpädagogik ; Sportunterricht ; Sportwissenschaft
    In:
    Lichamelijke opvoeding, Bd. 96 (2008) H. 3, S. 8-10, 0024-2810
    Language:
    Dutch
    FIS Bildung Literaturdatenbank
  16. 16
    Staff View
    Publication Date:
    2018-03-27
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Semiconductors II: surfaces, interfaces, microstructures, and related topics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  17. 17
    Staff View
    Publication Date:
    2018-07-14
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    0031-9007
    Electronic ISSN:
    1079-7114
    Topics:
    Physics
    Keywords:
    Condensed Matter: Structure, etc.
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  18. 18
    Dura, J. A. ; Richter, C. A. ; Majkrzak, C. F. ; Nguyen, N. V.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1998
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We present here a comparison of neutron reflectometry, x-ray reflectometry, and spectroscopic ellipsometry on a thin oxide film. These three probes each independently determine the structure of the film as a function of depth. We find an excellent agreement between the three techniques for measurements of thicknesses and interfacial roughnesses for both the SiO2 and surface contamination layers found in the sample. Realistic models based on interface parameters measured herein indicate that as the SiO2 layers decrease to sizes projected for future generations of electronic devices, both spectroscopic ellipsometry and neutron reflectometry can easily measure SiO2 films to 2 nm thick or less.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Dura, J. A. ; Pellegrino, J. G. ; Richter, C. A.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    To explore the role of interface scattering in high electron mobility transistor (HEMT) device performance, a series of samples consisting of both a superlattice and a HEMT structure were grown by molecular beam epitaxy (MBE) at temperatures ranging from 500 to 630 °C. Hall measurements indicate a trend toward higher mobilities in samples grown at higher temperatures. Subsequent x-ray reflectivity measurements were made, and the data were fitted by least-squares refinement of a calculated reflectivity curve determined from a model of the sample structure to obtain the composition profile along the growth direction. These results indicate smoother interfaces for the samples with higher mobilities. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Cho, Yong Jai ; Nguyen, N. V. ; Richter, C. A. ; Ehrstein, J. R.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 2002
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The optical properties of a set of high-k dielectric HfO2 films annealed at various high temperatures were determined by spectroscopic ellipsometry. The results show that the characteristics of the dielectric functions of these films are strongly affected by high temperature annealing. For a sample annealed at 600 °C, the film becomes polycrystalline, and its dielectric function displays a distinctive peak at 5.9 eV. On the other hand, the film remains amorphous without the 5.9 eV feature after 500 °C annealing. To model the dielectric functions, the Tauc–Lorentz dispersion was successfully adopted for these amorphous and polycrystalline films. The absorption edge was observed to shift to a higher energy at a high temperature annealing. Defects in the films were shown to relate to the appearance of a band tail above the absorption edge, and they appear to diminish with high temperature annealing. © 2002 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses