Search Results - (Author, Cooperation:C. Nicholson)

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  1. 1
    L. Xie ; H. Kang ; Q. Xu ; M. J. Chen ; Y. Liao ; M. Thiyagarajan ; J. O'Donnell ; D. J. Christensen ; C. Nicholson ; J. J. Iliff ; T. Takano ; R. Deane ; M. Nedergaard
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-10-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adrenergic Antagonists/administration & dosage ; Amyloid beta-Peptides/*metabolism ; Animals ; Brain/*metabolism/physiology ; Cerebral Cortex/metabolism/physiology ; Cerebrospinal Fluid/metabolism ; Diffusion ; Electroencephalography ; Extracellular Space ; Intracellular Space ; Male ; Mice ; Mice, Inbred C57BL ; Neurodegenerative Diseases/*metabolism ; Quaternary Ammonium Compounds/chemistry ; Receptors, Adrenergic/metabolism ; Sleep/*physiology ; Wakefulness/physiology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    N. D. Young ; F. Debelle ; G. E. Oldroyd ; R. Geurts ; S. B. Cannon ; M. K. Udvardi ; V. A. Benedito ; K. F. Mayer ; J. Gouzy ; H. Schoof ; Y. Van de Peer ; S. Proost ; D. R. Cook ; B. C. Meyers ; M. Spannagl ; F. Cheung ; S. De Mita ; V. Krishnakumar ; H. Gundlach ; S. Zhou ; J. Mudge ; A. K. Bharti ; J. D. Murray ; M. A. Naoumkina ; B. Rosen ; K. A. Silverstein ; H. Tang ; S. Rombauts ; P. X. Zhao ; P. Zhou ; V. Barbe ; P. Bardou ; M. Bechner ; A. Bellec ; A. Berger ; H. Berges ; S. Bidwell ; T. Bisseling ; N. Choisne ; A. Couloux ; R. Denny ; S. Deshpande ; X. Dai ; J. J. Doyle ; A. M. Dudez ; A. D. Farmer ; S. Fouteau ; C. Franken ; C. Gibelin ; J. Gish ; S. Goldstein ; A. J. Gonzalez ; P. J. Green ; A. Hallab ; M. Hartog ; A. Hua ; S. J. Humphray ; D. H. Jeong ; Y. Jing ; A. Jocker ; S. M. Kenton ; D. J. Kim ; K. Klee ; H. Lai ; C. Lang ; S. Lin ; S. L. Macmil ; G. Magdelenat ; L. Matthews ; J. McCorrison ; E. L. Monaghan ; J. H. Mun ; F. Z. Najar ; C. Nicholson ; C. Noirot ; M. O'Bleness ; C. R. Paule ; J. Poulain ; F. Prion ; B. Qin ; C. Qu ; E. F. Retzel ; C. Riddle ; E. Sallet ; S. Samain ; N. Samson ; I. Sanders ; O. Saurat ; C. Scarpelli ; T. Schiex ; B. Segurens ; A. J. Severin ; D. J. Sherrier ; R. Shi ; S. Sims ; S. R. Singer ; S. Sinharoy ; L. Sterck ; A. Viollet ; B. B. Wang ; K. Wang ; M. Wang ; X. Wang ; J. Warfsmann ; J. Weissenbach ; D. D. White ; J. D. White ; G. B. Wiley ; P. Wincker ; Y. Xing ; L. Yang ; Z. Yao ; F. Ying ; J. Zhai ; L. Zhou ; A. Zuber ; J. Denarie ; R. A. Dixon ; G. D. May ; D. C. Schwartz ; J. Rogers ; F. Quetier ; C. D. Town ; B. A. Roe
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-11-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Biological Evolution ; *Genome, Plant ; Medicago truncatula/*genetics/*microbiology ; Molecular Sequence Data ; Nitrogen Fixation/genetics ; Rhizobium/*physiology ; Soybeans/genetics ; *Symbiosis ; Synteny ; Vitis/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Nicholson, C. W., Lücke, A., Schmidt, W. G., Puppin, M., Rettig, L., Ernstorfer, R., Wolf, M.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-11-16
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Brahma, B. ; Forman, R.E. ; Stewart, E.E. ; Nicholson, C. ; Rice, M.E.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Ascorbate is an essential antioxidant in the CNS, localized predominantly in neuronal cytosol. Slices of mammalian brain rapidly lose ascorbate, however, when incubated in ascorbate-free media; brain slices also take up water and swell. Here we investigated water gain in coronal slices of rat forebrain incubated with and without ascorbate for 1-3 h at 34°C. Slices progressively gained water in ascorbate-free media, with a significant 12% water increase after 3 h at 34°C, compared with the water content of slices after a 1-h recovery period at 24°C, immediately following slice preparation. Inclusion of 400 μM ascorbate in the medium led to an increase in tissue ascorbate content and prevented water gain at 34°C. By contrast, water gain was not inhibited by isoascorbate or thiourea, which are antioxidants that are not accumulated in brain cells. The oxidant H2O2 enhanced water gain, whereas a cocktail of NMDA and non-NMDA receptor blockers inhibited edema formation to the same extent as ascorbate. These data demonstrate that brain edema, linked to glutamate-receptor activation, can result from intracellular oxidative stress and that this can be prevented by ascorbate.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.2000.741263.x

    Articles: DFG German National Licenses
  5. 5
    Nicholson, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1943
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.1943.tb05965.x

    Articles: DFG German National Licenses
  6. 6
    Nicholson, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1938
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.1938.tb11181.x

    Articles: DFG German National Licenses
  7. 7
    Mellberg, J. R. ; Franchi, G. J. ; Englander, H. R. ; Mosley, G. W. ; Nicholson, C. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1978
    Staff View
    ISSN:
    1600-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    abstract Three groups of approximately 200 children, consuming fluoridated water since birth, were given cither 5, 10 or 25 consecutive topical applications with an APF gel (1.2% F, pH 3.2) in mouthpieces. After 1 year, mean DMFS increments were 7.2%, 30.4% and 35.3% less respectively for the three groups as compared with untreated control groups. Although enamel fluoride levels remained high after the 1st year, differences in denial caries increments between treated and control groups were too small to show group differences. The results suggest that in a Fluoridated area, when caries activity is low, if would be difficult to show a long-term anticaries effect by increasing the fluoride con cent ration in sound enamel by a short series of self-applied topical fluoride applications.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0528.1978.tb01133.x

    Articles: DFG German National Licenses
  8. 8
    Joseph, L. ; Edwards, J. M. ; Nicholson, C. M. ; Pitt, M. A. ; Howat, A. J.

    Oxford, UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2303
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We have assessed the effectiveness and accuracy of reporting fine needle aspirates of the breast (FNAB) using a liquid-based cytology (LBC) system (the Cytospin® method) in the pressure situation of a rapid access clinic (RAC). We have reviewed every case from the RAC from June 1997 to February 2001 inclusive. There were 1322 cases, which accounted for 26% of the total FNAB received in our department over the period. There were 323 cancers and 999 benign cases in the group. The inadequate/nondiagnostic rate (C1) was 18%. The absolute sensitivity, including C1 cases, was 73% with the complete sensitivity being 90%. The groups of ‘atypical, probably benign’ (C3) and ‘suspicious, probably malignant’ (C4) accounted for a total of 6.2%. There were 28 false negative cases and 1 false positive case (a borderline phyllodes tumour).Comparing our results with the standards recommended by the NHSBSP has shown that the diagnosis of FNAB using this LBC method is feasible, accurate and reliable even in the pressure situation of a RAC.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2303.2002.00446.x

    Articles: DFG German National Licenses
  9. 9
    Nicholson, C. D. ; Broadley, K. J. ; Burden, D. T. ; Natoff, I. L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1979
    Staff View
    ISSN:
    1440-1681
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    1. Two benzofuran-2-ethanolamines Ro 03-5255 (l-(5-acetylamino-benzo-furan-2-yl)-l-hydroxy-2-isopropylaminoethane) and Ro 03-7894 (l-(5-chlora-cetyl aminobenzofuran-2-yl)-l-hydroxy-2-isopropylaminoethane) which had previously been shown to exhibit respectively competitive and irreversible β-adrenoceptor antagonism in guinea-pig isolated atria, were compared in vivo using isoprenaline-induced tachycardia of anaesthetized guinea-pigs and heart rate and contractility (dp/dtmax) of open-chest anaesthetized guinea-pigs and of conscious cats.2. In urethane-anaesthetized guinea-pigs doses of 3 mg/kg, s.c. of both antagonists produced significant blockade of the rate response to an 80% of maximum dose of isoprenaline after 4 h. In other experiments, guinea-pigs were pretreated with the antagonists and the responses to isoprenaline were then monitored. The slopes of the dose-response curves to isoprenaline were depressed for up to 24 h by Ro 03-7894 but this was not so with Ro 03-5255.3. In conscious cats the course of blockade by Ro 03-7894 was followed in the same animals and was still evident after 48 h. In contrast, the β-adrenoceptor blockade produced by Ro 03-5255 was not evident 24 h after administration.4. The persistence of blockade by Ro 03-7894 was consistent with the irreversible mode of action demonstrated in vitro.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1440-1681.1979.tb00044.x

    Articles: DFG German National Licenses
  10. 10
    KO, C.B. ; WALTON, S. ; KECZKES, K. ; BURY, H.P.R. ; NICHOLSON, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1994
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary A study of the incidence of skin cancer over a 14-year period in the North Humberside area of the U.K. indicates a steady rise in the numbers of the four most common types of skin cancer. A steep increase in the incidence of squamous cell carcinoma of the skin compared with that of internal squamous cell carcinoma was also detected.Our findings emphasize the need for continuing public education about both the dangers of UV radiation and measures to reduce exposure.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2133.1994.tb02920.x

    Articles: DFG German National Licenses
  11. 11
    FREEMAN, JOHN A. ; NICHOLSON, C. N.

    [s.l.] : Nature Publishing Group
    Published 1970
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Fig. 1. A, Diagram of frog cerebellum and experimental arrangement described in text, pc, Purkinje cell; gc, granule cell; pf, parallel fibre; mf, mossy fibre. B, Extracellular field potentials evoked by surface stimulation recorded simultaneously at two different points 250 mm apart on the same ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/226640a0

    Articles: DFG German National Licenses
  12. 12
    Nicholson, C.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0957-1787
    Keywords:
    Access pricing ; Postal services ; Regulation
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0957-1787(91)90090-R

    Articles: DFG German National Licenses
  13. 13
    NICHOLSON, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1986
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1749-6632.1986.tb27145.x

    Articles: DFG German National Licenses
  14. 14
    RICE, M. E. ; NICHOLSON, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1986
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1749-6632.1986.tb27171.x

    Articles: DFG German National Licenses
  15. 15
    Mellberg, J. R. ; Nicholson, C. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1974
    Staff View
    ISSN:
    1752-7325
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    These two investigators have completed a study of the uptake of F by the enamel of primary teeth which supplies some fundamental information about the topical effect of solutions of fluoride.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1752-7325.1974.tb00667.x

    Articles: DFG German National Licenses
  16. 16
    Nicholson, C. E. ; Wasilewski, W. H.

    Washington, etc. : Periodicals Archive Online (PAO)
    Published 1978
    Staff View
    ISSN:
    0014-4940
    Topics:
    Linguistics and Literary Studies
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1084-1978-036-03-000019

    Articles: DFG German National Licenses
  17. 17
    Jukna, J. J. ; Nicholson, C. D.
    Springer
    Published 1987
    Staff View
    ISSN:
    1432-1912
    Keywords:
    Denbufylline ; Pentoxifylline ; Blood viscosity ; Erythrocyte filterability ; Leucocyte filterability
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The novel alkylxanthine, denbufylline [1,3-di-n-butyl-7-(2-oxopropyl)-xanthine] has been examined, in vitro, for effects on the viscosity of rat whole blood and on the filterability of rat blood cell suspensions. For comparison, pentoxifylline was also examined for theological activity. Denbufylline reduced the viscosity of whole blood at all shear rates utilised, up to 128.5 s−1. The effect was, however, more pronounced at a low (0.7 s−1) than at a high (94.5 s−1) shear rate indicating that the compound reduces blood cell aggregation and increases blood cell deformability. Denbufylline also increased the filterability of blood cell suspensions. This is further evidence that the compound increases the deformability of blood cells. Denbufylline elevated the filterability of both pure erythrocyte and mixed erythrocyte/leucocyte suspensions, the effect being greatest with the latter. This suggests that denbufylline may influence the deformability of both red and white blood cells. However, the effect on white blood cells, under the experimental conditions employed, is apparently more marked. Pentoxifylline also reduced the viscosity of rat whole blood and increased the filterability of rat blood cell suspensions. However, denbufylline was 10–100-fold more potent in these tests than pentoxifylline.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00165561

    Articles: DFG German National Licenses
  18. 18
    NICHOLSON, C.

    Leiden : Periodicals Archive Online (PAO)
    Published 1989
    Staff View
    ISSN:
    0022-4200
    Topics:
    Ethnic Sciences
    Theology and Religious Studies
    Notes:
    "Reviews"
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:b184-1989-019-01-000010

    Articles: DFG German National Licenses
  19. 19
    Nicholson, C. E.

    Manchester, etc. : Periodicals Archive Online (PAO)
    Published 1979
    Staff View
    ISSN:
    0306-1973
    Topics:
    Linguistics and Literary Studies
    History
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:r575-1979-005-02-000004

    Articles: DFG German National Licenses
  20. 20
    NICHOLSON, C. E.

    Cambridge, etc. : Periodicals Archive Online (PAO)
    Published 1978
    Staff View
    ISSN:
    0306-2473
    Topics:
    English, American Studies
    Description / Table of Contents:
    REVIEWS
    Notes:
    American Literature: Special Number
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:m191-1978-008-00-000044

    Articles: DFG German National Licenses