Search Results - (Author, Cooperation:B. D. Mitchell)
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1Latest Papers from Table of Contents or Articles in PressP. van der Harst ; W. Zhang ; I. Mateo Leach ; A. Rendon ; N. Verweij ; J. Sehmi ; D. S. Paul ; U. Elling ; H. Allayee ; X. Li ; A. Radhakrishnan ; S. T. Tan ; K. Voss ; C. X. Weichenberger ; C. A. Albers ; A. Al-Hussani ; F. W. Asselbergs ; M. Ciullo ; F. Danjou ; C. Dina ; T. Esko ; D. M. Evans ; L. Franke ; M. Gogele ; J. Hartiala ; M. Hersch ; H. Holm ; J. J. Hottenga ; S. Kanoni ; M. E. Kleber ; V. Lagou ; C. Langenberg ; L. M. Lopez ; L. P. Lyytikainen ; O. Melander ; F. Murgia ; I. M. Nolte ; P. F. O'Reilly ; S. Padmanabhan ; A. Parsa ; N. Pirastu ; E. Porcu ; L. Portas ; I. Prokopenko ; J. S. Ried ; S. Y. Shin ; C. S. Tang ; A. Teumer ; M. Traglia ; S. Ulivi ; H. J. Westra ; J. Yang ; J. H. Zhao ; F. Anni ; A. Abdellaoui ; A. Attwood ; B. Balkau ; S. Bandinelli ; F. Bastardot ; B. Benyamin ; B. O. Boehm ; W. O. Cookson ; D. Das ; P. I. de Bakker ; R. A. de Boer ; E. J. de Geus ; M. H. de Moor ; M. Dimitriou ; F. S. Domingues ; A. Doring ; G. Engstrom ; G. I. Eyjolfsson ; L. Ferrucci ; K. Fischer ; R. Galanello ; S. F. Garner ; B. Genser ; Q. D. Gibson ; G. Girotto ; D. F. Gudbjartsson ; S. E. Harris ; A. L. Hartikainen ; C. E. Hastie ; B. Hedblad ; T. Illig ; J. Jolley ; M. Kahonen ; I. P. Kema ; J. P. Kemp ; L. Liang ; H. Lloyd-Jones ; R. J. Loos ; S. Meacham ; S. E. Medland ; C. Meisinger ; Y. Memari ; E. Mihailov ; K. Miller ; M. F. Moffatt ; M. Nauck ; M. Novatchkova ; T. Nutile ; I. Olafsson ; P. T. Onundarson ; D. Parracciani ; B. W. Penninx ; L. Perseu ; A. Piga ; G. Pistis ; A. Pouta ; U. Puc ; O. Raitakari ; S. M. Ring ; A. Robino ; D. Ruggiero ; A. Ruokonen ; A. Saint-Pierre ; C. Sala ; A. Salumets ; J. Sambrook ; H. Schepers ; C. O. Schmidt ; H. H. Sillje ; R. Sladek ; J. H. Smit ; J. M. Starr ; J. Stephens ; P. Sulem ; T. Tanaka ; U. Thorsteinsdottir ; V. Tragante ; W. H. van Gilst ; L. J. van Pelt ; D. J. van Veldhuisen ; U. Volker ; J. B. Whitfield ; G. Willemsen ; B. R. Winkelmann ; G. Wirnsberger ; A. Algra ; F. Cucca ; A. P. d'Adamo ; J. Danesh ; I. J. Deary ; A. F. Dominiczak ; P. Elliott ; P. Fortina ; P. Froguel ; P. Gasparini ; A. Greinacher ; S. L. Hazen ; M. R. Jarvelin ; K. T. Khaw ; T. Lehtimaki ; W. Maerz ; N. G. Martin ; A. Metspalu ; B. D. Mitchell ; G. W. Montgomery ; C. Moore ; G. Navis ; M. Pirastu ; P. P. Pramstaller ; R. Ramirez-Solis ; E. Schadt ; J. Scott ; A. R. Shuldiner ; G. D. Smith ; J. G. Smith ; H. Snieder ; R. Sorice ; T. D. Spector ; K. Stefansson ; M. Stumvoll ; W. H. Tang ; D. Toniolo ; A. Tonjes ; P. M. Visscher ; P. Vollenweider ; N. J. Wareham ; B. H. Wolffenbuttel ; D. I. Boomsma ; J. S. Beckmann ; G. V. Dedoussis ; P. Deloukas ; M. A. Ferreira ; S. Sanna ; M. Uda ; A. A. Hicks ; J. M. Penninger ; C. Gieger ; J. S. Kooner ; W. H. Ouwehand ; N. Soranzo ; J. C. Chambers
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Cycle/genetics ; Cytokines/metabolism ; Drosophila melanogaster/genetics ; Erythrocytes/cytology/*metabolism ; Female ; Gene Expression Regulation/genetics ; *Genetic Loci ; *Genome-Wide Association Study ; Hematopoiesis/genetics ; Hemoglobins/genetics ; Humans ; Male ; Mice ; Organ Specificity ; *Phenotype ; Polymorphism, Single Nucleotide/genetics ; RNA Interference ; Signal Transduction/geneticsPublished by: -
2Latest Papers from Table of Contents or Articles in PressC. Gieger ; A. Radhakrishnan ; A. Cvejic ; W. Tang ; E. Porcu ; G. Pistis ; J. Serbanovic-Canic ; U. Elling ; A. H. Goodall ; Y. Labrune ; L. M. Lopez ; R. Magi ; S. Meacham ; Y. Okada ; N. Pirastu ; R. Sorice ; A. Teumer ; K. Voss ; W. Zhang ; R. Ramirez-Solis ; J. C. Bis ; D. Ellinghaus ; M. Gogele ; J. J. Hottenga ; C. Langenberg ; P. Kovacs ; P. F. O'Reilly ; S. Y. Shin ; T. Esko ; J. Hartiala ; S. Kanoni ; F. Murgia ; A. Parsa ; J. Stephens ; P. van der Harst ; C. Ellen van der Schoot ; H. Allayee ; A. Attwood ; B. Balkau ; F. Bastardot ; S. Basu ; S. E. Baumeister ; G. Biino ; L. Bomba ; A. Bonnefond ; F. Cambien ; J. C. Chambers ; F. Cucca ; P. D'Adamo ; G. Davies ; R. A. de Boer ; E. J. de Geus ; A. Doring ; P. Elliott ; J. Erdmann ; D. M. Evans ; M. Falchi ; W. Feng ; A. R. Folsom ; I. H. Frazer ; Q. D. Gibson ; N. L. Glazer ; C. Hammond ; A. L. Hartikainen ; S. R. Heckbert ; C. Hengstenberg ; M. Hersch ; T. Illig ; R. J. Loos ; J. Jolley ; K. T. Khaw ; B. Kuhnel ; M. C. Kyrtsonis ; V. Lagou ; H. Lloyd-Jones ; T. Lumley ; M. Mangino ; A. Maschio ; I. Mateo Leach ; B. McKnight ; Y. Memari ; B. D. Mitchell ; G. W. Montgomery ; Y. Nakamura ; M. Nauck ; G. Navis ; U. Nothlings ; I. M. Nolte ; D. J. Porteous ; A. Pouta ; P. P. Pramstaller ; J. Pullat ; S. M. Ring ; J. I. Rotter ; D. Ruggiero ; A. Ruokonen ; C. Sala ; N. J. Samani ; J. Sambrook ; D. Schlessinger ; S. Schreiber ; H. Schunkert ; J. Scott ; N. L. Smith ; H. Snieder ; J. M. Starr ; M. Stumvoll ; A. Takahashi ; W. H. Tang ; K. Taylor ; A. Tenesa ; S. Lay Thein ; A. Tonjes ; M. Uda ; S. Ulivi ; D. J. van Veldhuisen ; P. M. Visscher ; U. Volker ; H. E. Wichmann ; K. L. Wiggins ; G. Willemsen ; T. P. Yang ; J. Hua Zhao ; P. Zitting ; J. R. Bradley ; G. V. Dedoussis ; P. Gasparini ; S. L. Hazen ; A. Metspalu ; M. Pirastu ; A. R. Shuldiner ; L. Joost van Pelt ; J. J. Zwaginga ; D. I. Boomsma ; I. J. Deary ; A. Franke ; P. Froguel ; S. K. Ganesh ; M. R. Jarvelin ; N. G. Martin ; C. Meisinger ; B. M. Psaty ; T. D. Spector ; N. J. Wareham ; J. W. Akkerman ; M. Ciullo ; P. Deloukas ; A. Greinacher ; S. Jupe ; N. Kamatani ; J. Khadake ; J. S. Kooner ; J. Penninger ; I. Prokopenko ; D. Stemple ; D. Toniolo ; L. Wernisch ; S. Sanna ; A. A. Hicks ; A. Rendon ; M. A. Ferreira ; W. H. Ouwehand ; N. Soranzo
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Blood Platelets/*cytology/metabolism ; Cell Size ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Europe ; Gene Expression Profiling ; Gene Silencing ; Genome, Human/genetics ; Genome-Wide Association Study ; Hematopoiesis/*genetics ; Humans ; Megakaryocytes/*cytology/metabolism ; Platelet Count ; Protein Interaction Maps ; Transcription, Genetic/genetics ; Zebrafish/genetics ; Zebrafish Proteins/geneticsPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1365-2427Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: SUMMARY. The seasonal distribution of Parartemia zietziana and Artemia salina was studied in a South Australian saltfield. P. zietziana occurred alone at salinities from 112 to 214%‰ and A. salina occurred alone at salinities above 285%‰; the two species overlapped in the range 214 to 285%‰. Respiration experiments indicated that A. salina had a lower ‘critical’ oxygen concentration than P. zietziana, apparently due to the presence of haemoglobin in A. salina. This may result in an adaptive advantage at high salinity and low dissolved oxygen.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesMitchell, B D ; Anderson, T ; Silva, S S ; Collins, R O ; Chavez, J R ; Jones, P L ; Austin, C M
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1365-2109Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: A production model is presented for semi-intensive freshwater crayfish culture ponds incorporating detrital forage. The conceptual model is developed from five submodels of trophic-dynamic interactions within the pond ecosystem. The model includes microbially enhanced detrital forage (MEDF) produced from plant matter grown in the pond as a significant component of nutrition. The model is proposed as an aid to understanding pond-based aquaculture techniques that rely upon manipulating the characteristics of MEDF. The significance of MEDF as a source of nutrition in aquaculture is discussed.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesMITCHELL, B. D. ; COLLINS, R. O. ; AUSTIN, C. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1365-2109Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The apparatus used was somewhat similar to that described by Grimshaw and Roberts1, in that oxygen was passed over the sample in a porous, ceramic holder block at a rate of 200 ml./min. Samples consisted of 10 mgm. oven-dried peat diluted with 190 mgm. calcined kaolinite, the inert material being ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesHaffner, S. M. ; Gonzales, C. ; Valdez, R. A. ; Mykkänen, L. ; Hazuda, H. P. ; Mitchell, B. D. ; Monterrosa, A. ; Stern, M. P.
Springer
Published 1993Staff ViewISSN: 1432-0428Keywords: Microalbuminuria ; Type 2 (non-insulin-dependent) diabetes mellitus ; dyslipidaemia ; blood pressure ; insulin resistanceSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Microalbuminuria is associated with increased cardiovascular mortality in both diabetic and non-diabetic subjects. A number of studies have indicated that insulin resistance, increased blood pressure and dyslipidaemia precede the onset of clinical diabetes. We examined various correlates of microalbuminuria in 1,298 non-diabetic subjects who participated in the Mexico city Diabetes Study, a population-based study of diabetes and cardiovascular risk factors. Both parental history of diabetes and impaired glucose tolerance were significantly associated with microalbuminuria. These results were not explained by differences in age or blood pressure between subjects with or without a parental history of diabetes or impaired glucose tolerance. In addition, subjects with microalbuminuria had increased 2-h insulin and triglyceride concentrations, a higher prevalence of hypertension, and decreased high density lipoprotein cholesterol concentrations relative to subjects without microalbuminuria. These results suggest that microalbuminuria may be a feature of the prediabetic state.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesMitchell, B. D. ; Kammerer, C. M. ; Reinhart, L. J. ; Stern, M. P. ; MacCluer, J. W.
Springer
Published 1995Staff ViewISSN: 1432-0428Keywords: Key words NIDDM ; family studies ; inheritance ; genetics ; Mexican Americans.Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Family studies have demonstrated that there is a strong genetic component to the aetiology of non-insulin-dependent diabetes mellitus (NIDDM), although the mode of inheritance is unknown. A number of recent family history studies, including one in Mexican Americans, have suggested that there is an excess of maternal transmission of NIDDM. Family history studies are subject to various types of bias, however, and the potential for bias in many of these studies has not been thoroughly evaluated. We therefore tested the hypothesis that diabetes is more likely to be transmitted from mothers than from fathers using data collected from a large family study of low-income Mexican Americans in San Antonio, Texas. The parents and offspring from 318 different nuclear families attended our medical clinic, where they received a 2-h oral glucose test. Diabetes was diagnosed on the basis of World Health Organization criteria. The sibships were classified into diabetic sibships (at least one sibling in the sibship was diabetic; n = 54) and non-diabetic siblings (no diabetic siblings; n = 264). The prevalence of diabetes among mothers of diabetic siblings was 61.4 % (27 of 44) compared to 64.3 % (18 of 28) among fathers of diabetic siblings (rate ratio = 0.95; 95 % confidence interval: 0.51–1.84). For the non-diabetic sibships, the prevalence of diabetes was 31.7 % (78 of 246) and 28.9 % (37 of 128) among mothers and fathers, respectively (rate ratio = 1.09; 95 % confidence interval: 0.73–1.67). These data provide no evidence for an excess maternal transmission of diabetes in Mexican Americans. [Diabetologia (1995) 38: 314–317]Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1432-0428Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesMitchell, B. D. ; Kammerer, C. M. ; Reinhart, L. J. ; Stern, M. P. ; MacCluer, J. W.
Springer
Published 1995Staff ViewISSN: 1432-0428Keywords: NIDDM ; family studies ; inheritance ; genetics ; Mexican AmericansSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Family studies have demonstrated that there is a strong genetic component to the aetiology of non-insulin-dependent diabetes mellitus (NIDDM), although the mode of inheritance is unknown. A number of recent family history studies, including one in Mexican Americans, have suggested that there is an excess of maternal transmission of NIDDM. Family history studies are subject to various types of bias, however, and the potential for bias in many of these studies has not been thoroughly evaluated. We therefore tested the hypothesis that diabetes is more likely to be transmitted from mothers than from fathers using data collected from a large family study of low-income Mexican Americans in San Antonio, Texas. The parents and offspring from 318 different nuclear families attended our medical clinic, where they received a 2-h oral glucose test. Diabetes was diagnosed on the basis of World Health Organization criteria. The sibships were classified into diabetic sibships (at least one sibling in the sibship was diabetic; n=54) and non-diabetic siblings (no diabetic siblings; n=264). The prevalence of diabetes among mothers of diabetic siblings was 61.4% (27 of 44) compared to 64.3% (18 of 28) among fathers of diabetic siblings (rate ratio=0.95; 95% confidence interval: 0.51–1.84). For the non-diabetic sibships, the prevalence of diabetes was 31.7% (78 of 246) and 28.9% (37 of 128) among mothers and fathers, respectively (rate ratio=1.09; 95% confidence interval: 0.73–1.67). These data provide no evidence for an excess maternal transmission of diabetes in Mexican Americans.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1432-0428Keywords: Hyperinsulinaemia ; insulin resistance ; syndrome X ; San Antonio Heart StudySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary In a population-based survey of 2,930 subjects, prevalence rates for obesity, Type 2 (non-insulin-dependent) diabetes mellitus, impaired glucose tolerance, hypertension, hypertriglyceridaemia, and hypercholesterolaemia were 54.3, 9.3, 11.1, 9.8, 10.3 and 9.2%, respectively. The prevalence, however, of each of these conditions in its isolated form (free of the other five) was 29.0% for obesity, 1.3% for Type 2 diabetes, 1.8% for impaired glucose tolerance, 1.5% for hypertension, 1.0% for hypertriglyceridaemia, and 1.7% for hypercholesterolaemia. Two-by-two associations were even rarer. The large differences in prevalence between isolated and mixed forms indicate a major overlap among the six disorders in multiple combinations. In the isolated form, each condition was characterized by hyperinsulinaemia (both fasting and 2 h after oral glucose), suggesting the presence of insulin resistance. In addition, in any isolated condition most of the variables categorising other members of the sextet were still significantly altered in comparison with 1,049 normal subjects. In the whole of the subjects who presented with one or another disorder (1,881 of 2,930 or 64%), marked fasting and post-glucose hyperinsulinaemia was associated with higher body mass index, waist:hip ratio, fasting and post-glucose glycaemia, systolic and diastolic blood pressure, serum triglycerides and total cholesterol levels, and with lower HDL-cholesterol concentrations (all p 〈0.001). We conclude that (1) insulin sensitivity, glucose tolerance, blood pressure, body fat mass and distribution, and serum lipids are a network of mutually interrelated functions; and (2) an insulin resistance syndrome underlies each and all of the six disorders carrying an increased risk of coronary artery disease.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1572-8943Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Résumé Un équipement d'analyse thermique différentielle de précision a permis de déceler et d'estimer d'une manière sensible et précise la gibbsite dans les argiles du sol. En procédant à la dissolution du carbonate de sodium, combinée avec l'étude par ATD, on peut distinguer la gibbsite bienordonnée dans une substance alumineuse peu-ordonnée.Abstract: Zusammenfassung Eine Präzisions-DTA-Einrichtung gestattet den empfindlichen und genauen Nachweis sowie die Bestimmung von Gibbsit in Tonmineralien. Wird die Methode mit einem Natriumkarbonat-Auflöseverfahren kombiniert, so ist es möglich, den gutgeordneten Gibbsit von schlechter geordneten aluminiumhaltigen Verbindungen zu unterscheiden.Notes: Abstract Precision differential thermal analysis (DTA) equipment provides a sensitive and accurate means of detecting and estimating gibbsite in soil clays. A combination of DTA and sodium carbonate dissolution procedures enables well-ordered gibbsite to be distinguished from poorly-ordered aluminous material.Type of Medium: Electronic ResourceURL: