Search Results - (Author, Cooperation:A. Lai)
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1Staff View
Publication Date: 2018-01-30Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
2Prasad, B., Bhatt, D. K., Johnson, K., Chapa, R., Chu, X., Salphati, L., Xiao, G., Lee, C., Hop, C. E. C. A., Mathias, A., Lai, Y., Liao, M., Humphreys, W. G., Kumer, S. C., Unadkat, J. D.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-06-02Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0090-9556Electronic ISSN: 1521-009XTopics: Chemistry and PharmacologyMedicinePublished by: -
3Duan, H., de Navas, L. F., Hu, F., Sun, K., Mavromatakis, Y. E., Viets, K., Zhou, C., Kavaler, J., Johnston, R. J., Tomlinson, A., Lai, E. C.
The Company of Biologists
Published 2018Staff ViewPublication Date: 2018-04-14Publisher: The Company of BiologistsPrint ISSN: 0950-1991Electronic ISSN: 1477-9129Topics: BiologyPublished by: -
4Mohammed, J., Flynt, A. S., Panzarino, A. M., Mondal, M. M. H., De; Cruz, M., Siepel, A., Lai, E. C.
Cold Spring Harbor Laboratory Press
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: Cold Spring Harbor Laboratory PressElectronic ISSN: 1549-5469Topics: BiologyMedicinePublished by: -
5Staff View
Publication Date: 2018-03-12Publisher: HindawiPrint ISSN: 1687-5966Electronic ISSN: 1687-5974Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
6Lallo, A., Frese, K. K., Morrow, C. J., Sloane, R., Gulati, S., Schenk, M. W., Trapani, F., Simms, N., Galvin, M., Brown, S., Hodgkinson, C. L., Priest, L., Hughes, A., Lai, Z., Cadogan, E., Khandelwal, G., Simpson, K. L., Miller, C., Blackhall, F., O'Connor, M. J., Dive, C.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-10-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
7A. Lai ; Z. Du ; C. L. Gan ; C. A. Schuh
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-09-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
8K. J. Mavrakis ; E. R. McDonald, 3rd ; M. R. Schlabach ; E. Billy ; G. R. Hoffman ; A. deWeck ; D. A. Ruddy ; K. Venkatesan ; J. Yu ; G. McAllister ; M. Stump ; R. deBeaumont ; S. Ho ; Y. Yue ; Y. Liu ; Y. Yan-Neale ; G. Yang ; F. Lin ; H. Yin ; H. Gao ; D. R. Kipp ; S. Zhao ; J. T. McNamara ; E. R. Sprague ; B. Zheng ; Y. Lin ; Y. S. Cho ; J. Gu ; K. Crawford ; D. Ciccone ; A. C. Vitari ; A. Lai ; V. Capka ; K. Hurov ; J. A. Porter ; J. Tallarico ; C. Mickanin ; E. Lees ; R. Pagliarini ; N. Keen ; T. Schmelzle ; F. Hofmann ; F. Stegmeier ; W. R. Sellers
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-02-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cell Survival ; Cyclin-Dependent Kinase Inhibitor p16/genetics/*metabolism ; Deoxyadenosines/metabolism ; Gene Deletion ; Humans ; Methionine/*metabolism ; Neoplasms/drug therapy/genetics/*metabolism ; Protein-Arginine N-Methyltransferases/genetics/*metabolism ; Purine-Nucleoside Phosphorylase/genetics/*metabolism ; RNA, Small Interfering/genetics ; Thionucleosides/metabolismPublished by: -
9Lai A Fat, Esther J. S. K. ; Vrede, Martinus A. ; Soetosenojo, Ramon M. ; Lai A Fat, Rudy F. M.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-4632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Cutaneous leishmaniasis is an endemic disease in Surinam. The disease was treated until the early 1970s with pentavalent antimony. Pentamidine mesylate was introduced by Niemel in 1973 for the treatment of cutaneous leishmaniasis in Surinam.Materials and methods In this retrospective study, we evaluate the results of treatment with pentamidine mesylate in 235 patients and with pentamidine isethionate in 80 patients.Results In the pentamidine mesylate- and pentamidine isethionate-treated groups, a cure rate (healing without relapse) of nearly 90% was found. Relapses were seen in approximately 10% of patients in both groups. Minor side-effects, such as pain at the injection site, bitter taste, and nausea, were seen with both drugs in about 65% of patients. Complaints of the respiratory tract were seen in less than 10% of patients in the pentamidine isethionate-treated group, but were uncommon in the pentamidine mesylate-treated group.Conclusions Pentamidine mesylate and isethionate have similar safety, efficacy, and side-effect profiles in the treatment of cutaneous leishmaniasis in Surinam.Type of Medium: Electronic ResourceURL: -
10Staff View
Publication Date: 2018-01-25Publisher: BMJ Publishing GroupPrint ISSN: 0022-2593Electronic ISSN: 1468-6244Topics: MedicineKeywords: Open accessPublished by: -
11Staff View
Publication Date: 2018-03-06Publisher: Oxford University PressPrint ISSN: 0923-7534Electronic ISSN: 1569-8041Topics: MedicinePublished by: -
12Staff View
Publication Date: 2018-03-14Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: genomics, bioinformaticsPublished by: -
13L.- P. Li; E. T. Dustrude; M. M. Haulcomb; A. R. Abreu; S. D. Fitz; P. L. Johnson; G. A. Thakur; A. I. Molosh; Y. Lai; A. Shekhar
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-08-15Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2158-3188Topics: MedicinePublished by: -
14FAT, R.F.M. LAI A ; SUURMOND, D. ; RÁDL, J. ; FURTH, R.
Oxford, UK : Blackwell Publishing Ltd
Published 1973Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A case of scleromyxoedema (lichen myxoedematosus) associated with an IgG1, type kappa paraproteinaemia is reported.Culture of bone marrow material demonstrated that this tissue synthesized monoclonal IgG (subclass γ I) with a light chain of type kappa. The culture of a biopsy specimen of the diseased skin demonstrated low-speed IgG synthesis. It is concluded that the bone marrow and pathological skin synthesize a paraprotein with the same characteristics as that in the serum.Microchemical analysis of pathological skin demonstrated an increase in the content of neutral glycoproteins, hyaluronic acid and chondroitin sulphates as well as the presence of heparin and keratan sulphates.It could not be demonstrated that the serum of this patient contained antibody against connective tissue ground substance or other skin constituents.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1365-2214Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Summary This study was conducted in Guangzhou, China. It compared the responses on stress scales of three groups of parents: (1) parents of children with HBV attending a special health kindergarten; (2) parents of children with HBV who stayed at home; and (3) parents of healthy children attending ordinary kidndergartens. Parents of HBV infected children reported greater problems due to stress. The stress was correlated with parents' general health in the three groups. The groups did not differ in reports of stress arising from life events other than the child's illness.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1600-0560Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: This review shows that useful information about immunological mechanisms of pathogenesis can be obtained from observations of human skin and appropriate animal models. Although the immunological mechanisms in skin and mucous membranes are becoming better known, much research remains to be done.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1600-0560Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Two cases are reported, one of multiple myeloma and the other of erythrodermia (malignant reticulosis?), the former associated with a Bence-Jones paraprotein and the latter with IgM paraproteinemia. With an in vitro culture technique and/or the immunofluorescence method it could be demonstrated that the paraprotein present in the serum was synthesized not only in the bone marrow but also in the lesional skin.Type of Medium: Electronic ResourceURL: -
18MOY, J. H. ; NIP, W. K. ; LAI, A. O. ; TSAI, W. Y. J. ; NAKAYAMA, T. O. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1980Staff ViewISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: A study was made of the effect of protein supplementation on the extrudability of tare flour. The tare flour was prepared from Bun-long taro corms by washing, peeling, slicing, air drying, and grinding prior to extrusion into rice, noodle, and macaroni. To improve the extrudability and nutritional qualities of these tare products, mung bean flour or soy protein were added to the dough before extrusion. Prepared with dough moisture content of 30% and 40% w/w, and dough temperatures of 21° and 82°C, extruded taro products were measured for their organoleptic (color, surface smoothness, and eating qualities) and objective (color, texture, protein level, and energy value) qualities. Results showed that the addition of 15% mung bean flour to taro flour improved the firmness, of the rice and noodle. Soy protein also improved the texture of taro rice with 30% and 40% dough moisture and macaroni with 30% dough moisture. The addition of either mung bean flour or soy protein improved the smoothness of taro rice only very little. Product color intensity (measured with extracts as the absorbance ratio of 520 nm/422 nm) decreased considerably in taro rice after the addition of soy protein or mung bean flour, but only slightly in taro noodle and macaroni. Hunter color measurements indicated we similar color in all the cooked, extruded taro samples. Protein supplement can be incorporated into the extruded taro samples to make them comparable in protein and energy level to conventional wheat products and rice. It was concluded that taro flour can be extruded successfully into rice, noodle or macaroni by proper adjustment of initial dough temperature and moisture content. Protein enrichment improved to a limited extent the overall quality of extruded tare samples.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1600-0668Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Architecture, Civil Engineering, SurveyingMedicineType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1600-0668Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Architecture, Civil Engineering, SurveyingMedicineType of Medium: Electronic ResourceURL: