Search Results - (Author, Cooperation:A. Frolov)
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1A. V. Shnyrova ; P. V. Bashkirov ; S. A. Akimov ; T. J. Pucadyil ; J. Zimmerberg ; S. L. Schmid ; V. A. Frolov
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-03-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Biocatalysis ; Dynamin I/*chemistry/*metabolism ; Guanosine Triphosphate/metabolism ; Hydrolysis ; Lipid Bilayers/chemistry/*metabolism ; Models, Biological ; Nanotubes ; Protein Conformation ; Protein Multimerization ; Protein Structure, Tertiary ; ThermodynamicsPublished by: -
2V E Kosenko, V D Zvonar, M A Ilin, V E Chebotarev and A A Frolov
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-12-02Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
3J. Qin ; S. P. Wu ; C. J. Creighton ; F. Dai ; X. Xie ; C. M. Cheng ; A. Frolov ; G. Ayala ; X. Lin ; X. H. Feng ; M. M. Ittmann ; S. J. Tsai ; M. J. Tsai ; S. Y. Tsai
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; COUP Transcription Factor II/deficiency/genetics/*metabolism ; Cell Cycle Checkpoints ; Cell Line, Tumor ; *Cell Transformation, Neoplastic ; Disease Models, Animal ; Disease Progression ; Gene Deletion ; Humans ; Male ; Mice ; Neoplasm Metastasis ; PTEN Phosphohydrolase/deficiency/genetics ; Proportional Hazards Models ; Prostate/metabolism/pathology ; Prostatic Neoplasms/*metabolism/*pathology ; *Signal Transduction ; Smad4 Protein/deficiency/genetics/metabolism ; Transforming Growth Factor beta/*antagonists & inhibitors/metabolismPublished by: -
4J. P. Mattila ; A. V. Shnyrova ; A. C. Sundborger ; E. R. Hortelano ; M. Fuhrmans ; S. Neumann ; M. Muller ; J. E. Hinshaw ; S. L. Schmid ; V. A. Frolov
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-07-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
5J. Geng ; K. Kim ; J. Zhang ; A. Escalada ; R. Tunuguntla ; L. R. Comolli ; F. I. Allen ; A. V. Shnyrova ; K. R. Cho ; D. Munoz ; Y. M. Wang ; C. P. Grigoropoulos ; C. M. Ajo-Franklin ; V. A. Frolov ; A. Noy
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-10-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biological Transport ; CHO Cells ; Cell Membrane/*chemistry/*metabolism ; Cell Survival ; Cricetulus ; DNA/metabolism ; HEK293 Cells ; Humans ; Ion Channels/metabolism ; Lipid Bilayers/*chemistry/*metabolism ; Liposomes ; *Nanotubes, Carbon/ultrastructure ; Porins/chemistry/*metabolism ; *Stochastic ProcessesPublished by: -
6Staff View
Type of Medium: articlePublication Date: 1985Keywords: Bildungstheorie ; Biografie ; Makarenko, Anton SemjonowitschIn: Vergleichende Pädagogik, Bd. 21 (1985) H. 2, S. 150-156, 0042-39200505-3072Language: facet.language.fre, facet.language.ger, facet.language.eng, facet.language.rusNote: Literaturangaben -
7Staff View
Type of Medium: articlePublication Date: 2002Keywords: Erziehung ; Historische Pädagogik ; Erziehungsmittel ; Bildungsgeschichte ; Schule ; Lebensnähe ; RusslandIn: Pedagogika (Moskau), (2002) H. 6, S. 71-77, 0869-561XLanguage: RussianNote: Literaturangaben 7 -
8Alhaj Abed, J., Ghotbi, E., Ye, P., Frolov, A., Benes, J., Jones, R. S.
The Company of Biologists
Published 2018Staff ViewPublication Date: 2018-12-11Publisher: The Company of BiologistsPrint ISSN: 0950-1991Electronic ISSN: 1477-9129Topics: BiologyPublished by: -
9Aliev, Yu. M. ; Frolov, A. A. ; Stenflo, L. ; Shukla, P. K.
New York, NY : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsNotes: It is demonstrated that the magnetization current, which arises from the interaction of high-frequency electromagnetic waves with hot collisionless, unmagnetized electron plasmas, can be derived by means of the ten-moment system of hydrodynamic equations. It is pointed out that the magnetization current is solely associated with the thermal motion of the electrons, and that it therefore does not appear in cold plasmas. This expression for the magnetization current agrees with those derived previously from kinetic theory. The present derivation provides, however, a comparatively much clearer physical picture of the origin of this current. In the limit where the phase velocity is much larger than the electron thermal velocity, a new result for the high-frequency induced vorticity of the plasma is obtained. It is also shown that the magnetization current in this paper is responsible for a novel scattering mechanism in which the high-frequency electromagnetic waves are scattered off vortex motions.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1570-1468Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Conclusions 1. More effective storage of industrial wastes and clarification of water is realized on hydraulic-fill dumps of the thermally loaded type, and at the same time subsequent excavation of these dumps for using the wastes in the economy is facilitated. 2. Since the estimates obtained characterizing the thermal regime of the structure take into account the relationship between the incoming and dissipated heat regardless of the type of solid phase and its consistency, by means of the developed classification it is possible to substantiate the construction not only of dumps but also, by using various measures to maintain a thermally loaded state, hydraulic-fill structures in various climatic regions of the Soviet Union with consideration, of course, of the differences in the specific heat of the materials being placed.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1570-1468Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Conclusions 1. Treatment of the surfaces of construction joints is an expensive operation whose performance requires additional work by the concrete-placing equipment, which to some extent adversely affects the rate of concreting. 2. In recent years the surfaces of construction joints at foreign hydroprojects in the majority of cases have been treated by high-pressure (280–420 kg/cm2) water-air jets. Comparatively recently special concrete-setting retarders began to be used on foreign construction projects, thanks to which the time during which the concrete surfaces can be treated effectively by water-air jets is increased. 3. The spreading and brushing of a thin layer of sand-cement mortar onto the surface of horizontal construction joints for a long time was standard practice abroad in preparing the joints before placing the concrete in the next blocks. Investigations conducted in recent years did not confirm the superiority of a joint with an underlying layer of mortar with respect to cohesion and density over a joint on which the sand-cement mortar was not placed. In connection with this many design organizations in a number of countries and particularly in the U.S.A. do not include the placement of an underlying layer in the concreting technical specifications. This saves cement (about 2%) and reduces labor costs for preparing the blocks for concreting and increases the efficiency of concrete plants and concrete-placing equipment.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1432-5411Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The best variational energies obtained to date for the ground states of all μ-mesomolecules are presented. The results are of rather high accuracy and can serve as a theoretical basis for the experimental study of three-body systems. The energies of thee − e + e −,∞H− and 11 S, 23 S, 23 P, 23 P states of∞He are calculated using the same method.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1090-6487Keywords: 76.60.Lz ; 75.25.+z.466Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The 57 Fe spin echo spectra were studied in local magnetic fields of a BiFeO3 ferroelectric antiferromagnet over the temperature range 77–304 K. The line shape analysis confirmed the presence of a spatially modulated, incommensurate cycloidal spin structure in BiFeO3 and allowed the actual spin distribution to be reproduced throughout the cycloid length. The distribution was found to be essentially anharmonic. The modulated structure is stable over the whole temperature range studied. The cycloid wave becomes more harmonic with temperature elevation.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1432-1106Keywords: Motor cortex ; Conditioned movement ; Posture ; Balance control ; CatSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The role of the sensorimotor cortex in the postural adjustments associated with conditioned paw lifting movements was investigated in the cat. Cats were trained to stand quietly on four strain gauge equipped platforms and to perform a lift-off movement with one forelimb when a conditioned tone was presented. The parameters recorded were the vertical forces exerted by the paws on each platform, the lateral and antero-posterior displacements of rods implanted on the T2, T12, L5 vertebrae as well as their rotation, and the EMG of triceps and biceps of both forelimbs. Before lesion, the postural adjustment consisted of a “nondiagonal” pattern where the CG was displaced laterally inside the triangle formed by the three remaining supporting limbs. Here a lateral bending of the thoracic column toward the supporting forelimb could be observed. The associated EMG pattern consisted of an early activation of the triceps lateral head in the moving limb which was probably responsible for the body displacement toward the opposite side, and a late biceps activation associated with the lift. In the supporting forelimb, a coactivation of the biceps and triceps was usually present. After contralateral sensorimotor lesion, the conditioned lifting movements were lost for 4–15 days after the lesion, before being subsequently recovered. The same lateral CG displacement and bending of the back was seen after lesion as before, which indicates that the goal of postural adjustment was preserved. However, the means of reaching it were modified. In most of the intact animals, the CG displacement was achieved in one step, whereas in the animals with lesions, the displacement was made either according to a slow ramp mode or in a discontinuous manner involving several steps. The mechanisms responsible for this disturbance are discussed.Type of Medium: Electronic ResourceURL: -
15Biryukova, E. V. ; Roschin, V. Y. ; Frolov, A. A. ; Ioffe, M. E. ; Massion, J. ; Dufosse, M.
Springer
Published 1999Staff ViewISSN: 1432-1106Keywords: Key words Posture maintenance ; Bimanual unloading ; Joint stiffness ; Equilibrium angle ; Invariant characteristicsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract In this study, the equilibrium-point hypothesis of muscle-torque generation is used to evaluate the changes in central control parameters in the process of postural-maintenance learning. Muscle torque is described by a linear spring equation with modifiable stiffness, viscosity, and equilibrium angle. The stiffness is considered to be the estimation of the central command for antagonist-muscle coactivation and the equilibrium angle to be the estimation of the reciprocal command for a shift of invariant characteristics of the joint. In the experiments, a load applied to the forearm was released. The subjects were instructed to maintain their forearm in the initial horizontal position. Five sessions of approximately twenty trials each were carried out by eight subjects. During two ”control” series, the load release was triggered by the experimenter. During three ”learning” series, the load supported by one forearm was released by the subject’s other hand. The elbow-joint angle, the angular acceleration, and the external load on the postural forearm were recorded. These recordings as well as anthropometric forearm characteristics were used to calculate the elbow-joint torque (which we called ”experimental”). Linear regression analysis was performed to evaluate the equilibrium angle, joint stiffness, and viscosity at each trial. The ”theoretical” torque was calculated using a linear spring equation with the found parameters. The good agreement observed between experimental and theoretical joint-torque time courses, apart from the very early period following unloading, argues in favor of the idea that the movement was mainly performed under a constant central command presetting the joint stiffness and the equilibrium angle. An overall increase in the stiffness occurred simultaneously with a decrease in the equilibrium angle during the ”learning” series in all the subjects. This suggests that subjects learn to compensate for the disturbing effects of unloading by increasing the joint stiffness. The mechanism possibly responsible for the presetting of the central control parameters is discussed.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-0770Source: Springer Online Journal Archives 1860-2000Topics: BiologyComputer SciencePhysicsNotes: Abstract. It has been widely claimed that linear models of the neuromuscular apparatus give very inaccurate approximations of human arm reaching movements. The present paper examines this claim by quantifying the contributions of the various non-linear effects of muscle force generation on the accuracy of linear approximation. We performed computer simulations of a model of a two-joint arm with six monarticular and biarticular muscles. The global actions of individual muscles resulted in a linear dependence of the joint torques on the joint angles and angular velocities, despite the great non-linearity of the muscle properties. The effect of time delay in force generation is much more important for model accuracy than all the non-linear effects, while ignoring this time delay in linear approximation results in large errors. Thus, the viscosity coefficients are rather underestimated and some of them can even be paradoxically estimated to be negative. Similarly, our computation showed that ignoring the time delay resulted in large errors in the estimation of the hand equilibrium trajectory. This could explain why experimentally estimated hand equilibrium trajectories may be complex, even during a simple reaching movement. The hand equilibrium trajectory estimated by a linear model becomes simple when the time delay is taken into account, and it is close to that actually used in the non-linear model. The results therefore provide a theoretical basis for estimating the hand equilibrium trajectory during arm reaching movements and hence for estimating the time course of the motor control signals associated with this trajectory, as set out in the equilibrium point hypothesis.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1090-6525Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Planar n-p-n transistors are fabricated with various profiles of the base impurity distribution, and their electrical parameters are investigated. An equation for calculating the breakdown voltage of the collector-base junction is proposed on the basis of an experimental data analysis. It is shown that the use of a planar p-n junction raises the collector junction breakdown voltages of planar n-p-n transistors.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1090-6525Source: Springer Online Journal Archives 1860-2000Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1573-9171Keywords: free-radical reactions ; carbohydrates ; chiral cyclopentanesSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract The decisive influence of the carboxyl group on the methanolysis of 3-methoxy-4-methoxycarbonylmethyl-2-oxabicyclo[2.2.1.]heptanes was proved experimentally, and several routes of conversion of the latter to the corresponding cyclopentanes were found.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1573-9171Keywords: free radical reactions ; carbohydrates ; chiral cyclopentanes ; chiral tetrahydrofuransSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract The benzyloxy group at C(4) of the pyranose ring in 3,4-disubstituted and 3-deoxy carbohydrate derivatives affects the direction of intramolecular free-radical C(2)-C(6) cyclization. A possible mechanism of the formation of the tetrahydrofuran ring was proposed.Type of Medium: Electronic ResourceURL: