Search Results - (Author, Cooperation:A. Ansari)

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  1. 1
  2. 2
    Staff View
    Publication Date:
    2018-04-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Biochemistry, Molecular Biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    J Husain and M A Ansari
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-09-29
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1757-8981
    Electronic ISSN:
    1757-899X
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
  5. 5
    Latest Papers from Table of Contents or Articles in Press
  6. 6
  7. 7
    DAVIS, P. A. ; FREGEAU, D. R. ; VAN DE WATER, J. ; SURH, C. ; ANSARI, A. ; COPPELL, R. ; DANNER, D. ; GERSHWIN, M. E.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Ansari, A ; Al-Rashed, S ; Oliver, D ; Harding, D

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    POWELL, JONATHAN D. ; BEDNARIK, DANIEL P. ; JEHUDA-COHEN, TAMAR ; VILLINGER, FRANCOIS ; FOLKS, THOMAS M. ; ANSARI, A. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Ansari, A. ; Hassan, C. ; Duley, J. ; Marinaki, A. ; Shobowale-Bakre, E. -M. ; Seed, P. ; Meenan, J. ; Yim, A. ; Sanderson, J.

    Oxford, UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background : Azathioprine therapy is discontinued in one-third of patients with inflammatory bowel disease because of toxicity or a lack of clinical response. Patients with thiopurine methyltransferase (TPMT) deficiency are intolerant to azathioprine, whilst carriers are at increased risk of side-effects.Aim : To evaluate the importance of TPMT activity in the management of azathioprine therapy in inflammatory bowel disease.Methods : Clinical response, adverse effects and haematological parameters were determined and correlated with TPMT enzyme activity and genotype in 106 patients with inflammatory bowel disease.Results : Ninety-six patients had high TPMT activity, and 10 had intermediate activity. Nineteen patients (18%) were intolerant to azathioprine. Fifteen (16%) of those with high TPMT activity were intolerant, compared with five (50%) with intermediate activity [odds ratio (OR), 5.4; 95% confidence interval (CI), 1.5–19.8]. Complete remission was achieved in 63% of cases, and complete or partial remission in 79%. Interestingly, very high TPMT activity (〉 14 units/mL red blood cells) was significantly associated with non-response, irrespective of the time on azathioprine (OR, 0.21; 95% CI, 0.07–0.68). TPMT gene mutations correlated with TPMT activity.Conclusions : Inflammatory bowel disease patients with intermediate TPMT activity have an increased risk of azathioprine toxicity. Conversely, very high TPMT activity predicts treatment failure. TPMT genotype predicted TPMT phenotype in this study.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0301-4622
    Keywords:
    CO stretching band ; Conformational substate hierarchy ; Control mechanism ; Myoglobin ; Protein dynamics ; Protein relaxation
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Patel, R. ; Ansari, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Ansari, A. ; Salem, F.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0020-708X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Agrawal, B.K. ; Ansari, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Keywords:
    Nuclear structure
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Agrawal, B.K. ; Ansari, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Ansari, A. ; Nair, S.C.K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Agrawal, B.K. ; Ansari, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Ansari, A. ; Nair, S.C.K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Wust, E. ; Ansari, A. ; Mosel, U.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses